Journals / Marmara Medical Journal / 2019 / Cilt: 32 - Sayı: 2

Demographic, clinical and treatment characteristics of patients with Kaposi’s sarcoma: A single-center study

Pages
86–89
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Overall a complete response was observed in 9 (36%) patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The clinical, demographic and treatment characteristics of patients with Kaposi’s sarcoma (KS) are not well-defined.
📊
Key Findings & Data:Patients and Methods: A retrospective cohort study was done and all patients who were followed up in our specialized cutaneous tumors outpatient clinic with a diagnosis of KS between 2006 and 2018 were included in the study.
💡
Conclusion & Impact:Overall a complete response was observed in 9 (36%) patients.
🔬Design:Research Article
📍Scope:2006 Verileri
⚙️Variables:Cryotherapy · Kaposi’s sarcoma · Timolol

Abstract

Objective: The clinical, demographic and treatment characteristics of patients with Kaposi’s sarcoma (KS) are not well-defined. There is lack of consensus on treatment modalities. Thus, we aimed to define demographic, clinical characteristics and treatment outcomes in our cohort of patients with KS. Patients and Methods: A retrospective cohort study was done and all patients who were followed up in our specialized cutaneous tumors outpatient clinic with a diagnosis of KS between 2006 and 2018 were included in the study. Results: A total of 25 patients were included in the study. The mean age of the patients was 66 and 80% were male. The most common form of KS was classic type (80%). During a mean follow-up of 43 months, the most frequently administered treatments were cryotherapy, interferons, radiotherapy, topical imiquimod and topical timolol. Overall a complete response was observed in 9 (36%) patients. Conclusion: The clinical and demographic characteristics of our cohort match those observed in existing literature. We think that the use of local treatments such as cryotherapy, topical imiquimod should be used more frequently in patients with limited disease. Considering the efficacy of timolol in other vascular tumors, future prospective studies investigating the effects of timolol in KS are highly warranted.

🔖

Cite This Article

SALMAN, A., ÖZGEN, Z. Y. (2019). Demographic, clinical and treatment characteristics of patients with Kaposi’s sarcoma: A single-center study. Marmara Medical Journal, Cilt: 32 - Sayı: 2, 86–89. https://ajindex.com/articles/284279

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Geraminejad P, Memar O, Aronson I, Rady PL, Hengge U, Trying SK. Kaposi’s sarcoma and other manifestations of human herpesvirus 8. J Am Acad Dermatol 2002
  2. doi: 10.1067/mjd.2002.128383 2. Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. Kaposi sarcoma. Nat Rev Dis Primers 2019
  3. doi: 10.1038/s41572.019.0060-9 3. Feuerman EJ, Potruch-Eisenkraft S. Kaposi’s sarcoma. A follow-up of 38 patients. Dermatologica 1973
  4. doi: 10.1159/000252034 4. Schneider JW, Dittmer DP. Diagnosis and treatment of Kaposi sarcoma. Am J Clin Dermatol 2017
  5. doi: 10.1007/s40257.017.0270-4 5. Kandaz M, Bahat Z, Guler OC, Canyilmaz E, Melikoglu M, Yoney A. Radiotherapy in the management of classic Kaposi’s sarcoma: A single institution experience from Northeast Turkey. Dermatol Ther 2018
  6. doi: 10.1111/ dth.12605 6. Chalya PL, Mbunda F, Rambau PF, et al. Kaposi’s sarcoma: A 10-year experience with 248 patients at a single tertiary care hospital in Tanzania. BMC Res Notes 2015
  7. 1–10. doi: 10.1186/s13104.015.1348-9 7. Tiussi RM, Caus AL de O, Diniz LM, Lucas EA. Kaposi’s sarcoma: clinical and pathological aspects in patients seen at the Hospital Universitário Cassiano Antônio Moraes – Vitória – Espírito Santo – Brazil. An Bras Dermatol 2012
  8. 220–7. doi: 10.1590/S0365.059.6201200.020.0005 8. Errihani H, Berrada N, Raissouni S, Rais F, Mrabti H, Rais G. Classic Kaposi’s sarcoma in morocco: Clinico – epidemiological study at the national institute of oncology. BMC Dermatol 2011
  9. doi: 10.1186/1471-5945-11-15 9. Wu X-J, Kang X-J, An C-X, et al. One hundred and five Kaposi sarcoma patients: a clinical study in Xinjiang, Northwest of China. J Eur Acad Dermatol Venereol 2013
  10. 1545–52. doi: 10.1111/jdv.12349 10. Trinca S, Ricci P, Benedetti M, Trinca S, Ricci P, Comba P. High incidence of classic Kaposi’s sarcoma in Mantua, Po Valley, Northern Italy (1989–1998). Br J Cancer 2002
  11. 379–82. doi: 10.1054/bjoc.2001.1912 11. Su Ö, Onsun N, Arda H, Ümmetoğlu Ö, Pekdemir A. Clinical Features, Presence of Human Herpesvirus-8 and Treatment Results in Classic Kaposi Sarcoma. TURKDERM – Arch Turkish Dermatology Venerol 2008
  12. 6 12. Gülüş Demirel B, Koca R, Solak Tekin N, Onak Kandemir N, Doğan Gün B, Köktürk F. Classic Kaposi’s sarcoma: The clinical, demographic and teratment characteristics of seventy-four patients. TURKDERM – Arch Turkish Dermatology Venerol 2016
  13. 136–40. doi: 10.4274/ turkderm.35336 13. Demirkazik A, Oza