SavedAdd your journal

Journals / Marmara Medical Journal / 2019 / Cilt: 32 - Sayı: 3

Evaluation of residual tumors and recurrence rates of malignant melanoma and non-melanoma skin cancer of head and neck region

Fatma Nihal DURMUŞ KOCAASLAN
Ali Conor ALAKUS
Bülent SAÇAK
Özlem ÇELEBİLİLER
Pages
107–111
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our study results suggest that recurrence is associated with the localization and type of the tumor, but not with the age or sex of the patient.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, we aimed to evaluate residual tumors and recurrence rates of malignant melanoma (MM) and a non-melanoma skin cancer of (NMSC) head and neck region.
📊
Key Findings & Data:Patients and Methods: Medical data of a total of 398 lesions of 323 patients who underwent surgical excision for a basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM) were retrospectively analyzed.
💡
Conclusion & Impact:Conclusion: Our study results suggest that recurrence is associated with the localization and type of the tumor, but not with the age or sex of the patient.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Basal cell carcinoma · Squamous cell carcinoma · Malignant melanoma

Abstract

Objective: In this study, we aimed to evaluate residual tumors and recurrence rates of malignant melanoma (MM) and a non-melanoma skin cancer of (NMSC) head and neck region. Patients and Methods: Medical data of a total of 398 lesions of 323 patients who underwent surgical excision for a basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM) were retrospectively analyzed. All patients were classified according to age, sex, location of the tumor, histopathological diagnosis, lesion diameter, excision diameter, surgical margin status, and residual lesions and recurrence rates. Results: There were 244 lesions (61.3%) in 189 males and 154 lesions (38.7%) in 134 females. The most common type of skin cancer was BCC in 268 lesions (67%), followed by SCC in 122 (31%), and MM in eight (2%), respectively. Recurrence was seen in 3% of the NMSC cases and in 25% of the MM cases. There was a statistically significant correlation between the histopathological diagnosis and recurrence rates. Compared to NMSC, MM cases had a higher risk for recurrence (p=0.029). Conclusion: Our study results suggest that recurrence is associated with the localization and type of the tumor, but not with the age or sex of the patient.

🔖

Cite This Article

KOCAASLAN, F. N. D., ALAKUS, A. C., SAÇAK, B., ÇELEBİLİLER, Ö. (2019). Evaluation of residual tumors and recurrence rates of malignant melanoma and non-melanoma skin cancer of head and neck region. Marmara Medical Journal, Cilt: 32 - Sayı: 3, 107–111. https://ajindex.com/articles/283808

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. Scarabello A, Muti P. Epidemiology and prevention of cutaneous tumors. In: Baldi A, Pasquali P, Spugnini E P, eds. Skin Cancer: A Practical Approach. New York: Humana Press, 2014: 17-28. 10.1007/978-1-4614-7357-2_2 [2] Guy Jr GP, Thomas CC, Thompson T, Watson M, Massetti G.M, Richardson LC; Centers for Disease Control and Prevention (CDC). Vital signs: melanoma incidence and mortality trends and projections - United States, 1982-2030. MMWR - Morb Mortal Wkly Rep 2015: 64:591-6. [3] Gillard M, Wang T S, Johnson TM. Nonmelanoma cutaneous malignancies. In: Chang AE, Ganz PA, Hayes DF, et al., eds. Oncology: An Evidence-Based Approach. New York: Springer, 2006: 1102-18. [4] Jacobs GH, Rippey JJ, Altini M. Prediction of aggressive behavior in basal cell carcinoma. Cancer 1982;49:53-7. doi: 10.1155/2011/496910. [5] Thieu K, Ruiz M, Owens DM. Cells of origin and tumor-initiating cells for nonmelanoma skin cancers. Cancer Lett 2013;338:82-8. doi: 10.1016/j.canlet.2012.05.008. [6] Shashanka R, Smitha BR. Head and Neck Melanoma. ISRN Surgery 2012, Article ID 948302. doi: 10.5402/2012/948302. [7] Kwa RE, Campana K, Moy RL. Biology of cutaneous squamous cell carcinoma. Am Acad Dermatol 1992; 26:1-26. [8] Ouyang Y H. Skin cancer of the head and neck. seminars in Plastic Surgery. Semin Plas Surg 2010;24:117-26. doi: 10.1055/s-0030-1255329. [9] Leiter U, Eigentler T, Garbe C. Epidemiology of skin cancer. Adv Exp Med Biol 2014; 810:120-40. [10] Johnson TM, Rowe DE, Nelson BR, Swanson NA. Squamous cell carcinoma of the skin (excluding lip and oral mucosa). J Am Acad Dermatol 1992; 26:467-84. [11] Alam M, Ratner D. Cutaneous squamous-cell carcinoma. N Engl J Med 2001;344: 97-983 [12] Padgett JK, Hendrix J D, Jr. Cutaneous malignancies and their management. Otolaryngol Clin North Am 2001;34:523-53. [13] Fears TR, Scotto J. Estimating increases in skin cancer morbidity due to increases in ultraviolet radiation exposure. Cancer Invest 1983;1:119-26. [14] Scotto J, Fears TR, Fraumeni JF. Incidence of nonmelanoma skin cancer in the United States. NIH Pub No: 83-2433.
  2. Bethesda, MD: U.S. Department of Health and Human Services. 1983. [15] Hasan Z, Riffat F. Epidemiology and aetiology of non-melanoma skin cancer. In: Riffat F, Palme CE, Venesss M, editors. Non-Melanoma Skin Cancer of the Head and Neck. New Delhi: Springer, 2015: 1-9. doi: 10.1007/978-81-322-2497-6 [16] Lai V, Cranwell W, Sinclair R. Epidemiology of skin cancer in the mature patient. Clin Dermatol 2018;36:167-76