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Journals / Marmara Pharmaceutical Journal / 2017 / Cilt: 21 - Sayı: 2

Antibacterial, cytotoxicity, and phytotoxicity profiles of three medicinal plants collected from Pakistan

Abdur RAUF
Şengül UYSAL
Taibi BEN HADDA
Bina Shaheen SIDDIQUI
Haroon KHAN
Muhammad Atif KHAN
Muhammad IJAZ
Mohammad S. MUBARAK
Saud BAWAZEER
Tareq ABU-IZNEID
Ajmal KHAN
Umar FAROOQ
Pages
261–268
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Accordingly, the extracts and fractions of the aforementioned plants possess potential antibacterial, cytotoxic, and phytotoxic effects which could be useful in the search and development of new pharmaceutical agents.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The purpose of present research was to examine the antibacterial, cytotoxic, and phytotoxic profiles of three important Pakistani medicinal plants viz., Teucrium stocksianum, Chenopodium botrys, and Micromeria biflora.
📊
Key Findings & Data:Methanolic extracts and aqueous fractions exhibited significant cytotoxicity in a concentration-dependent manner.
💡
Conclusion & Impact:Accordingly, the extracts and fractions of the aforementioned plants possess potential antibacterial, cytotoxic, and phytotoxic effects which could be useful in the search and development of new pharmaceutical agents.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

The purpose of present research was to examine the antibacterial, cytotoxic, and phytotoxic profiles of three important Pakistani medicinal plants viz., Teucrium stocksianum, Chenopodium botrys, and Micromeria biflora. The antibacterial, cytotoxicity, and phytotoxicity activities of samples extracted from these plants were evaluated by a modified agar well-diffusion method, brine shrimps cytotoxic assay, and Lemna acquinoctialisbased phytotoxic assay, respectively. Results revealed marked susceptibility of both the crude extracts and the aqueous fractions of these plants against K. pneumonia and B. subtilis. Methanolic extracts and aqueous fractions exhibited significant cytotoxicity in a concentration-dependent manner. Similarly, an outstanding phytotoxic effect was observed for the extracts/ fractions. Accordingly, the extracts and fractions of the aforementioned plants possess potential antibacterial, cytotoxic, and phytotoxic effects which could be useful in the search and development of new pharmaceutical agents.

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Cite This Article

RAUF, A., UYSAL, Ş., HADDA, T. B., SIDDIQUI, B. S., KHAN, H., KHAN, M. A., IJAZ, M., MUBARAK, M. S., BAWAZEER, S., ABU-IZNEID, T., KHAN, A., FAROOQ, U. (2017). Antibacterial, cytotoxicity, and phytotoxicity profiles of three medicinal plants collected from Pakistan. Marmara Pharmaceutical Journal, Cilt: 21 - Sayı: 2, 261–268. https://ajindex.com/articles/283759

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