Journals / Marmara Pharmaceutical Journal / 2017 / Cilt: 21 - Sayı: 3

Influence of Pharmacist Recommendations for Chemotherapy-Related Problems in Diabetic Cancer Patients

Pages
603–611
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Clinical pharmacist is expected to provide a well-defined education and care to those patients and the outcomes of pharmacist recommendations may diminish and prevent many drug-related problems and adverse drug reactions and by this, influence patients’ desire to complete the course of chemotherapy.

📌 3 Key Takeaways

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Objective & Hypothesis:Drug related-problems pose additional worse outcomes in cancer patients treated with chemotherapy.
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Key Findings & Data:A prospective study carried out on 50 diabetic patients as a single group with new diagnosis of diverse cancer types eligible for chemotherapy adminitration recruited between September 2014 and April 2015 at the oncology unit in one of the Teaching and Research Hospital (Istanbul-Turkey).
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Conclusion & Impact:Clinical pharmacist is expected to provide a well-defined education and care to those patients and the outcomes of pharmacist recommendations may diminish and prevent many drug-related problems and adverse drug reactions and by this, influence patients’ desire to complete the course of chemotherapy.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Özet

Drug related-problems pose additional worse outcomes in cancer patients treated with chemotherapy. A vital role of the clinical pharmacist is the detection and prevention of drug- related problems. The provision of patient education is an important step to reduce and prevent drug-related problems during chemotherapy administration. The objective of this study was to assess the occurrence of drug-related problems and the importance of effective provision of patient education and appropriate recommendations by the clinical pharmacist in reducing and solving of these problems in diabetic patients suffering from cancer. A prospective study carried out on 50 diabetic patients as a single group with new diagnosis of diverse cancer types eligible for chemotherapy adminitration recruited between September 2014 and April 2015 at the oncology unit in one of the Teaching and Research Hospital (Istanbul-Turkey). Drug-related problems were evaluated, and proper patient education alongside pharmacist recommendation regarding chemotherapy was provided during the required chemotherapy protocol schedule. (n=65) of the drug-related problems were contributed to inappropriate IV fluid selection; (n=33) were attributed to low drug dose prescribed, and (n=30) to high drug dose prescribed. Drug-related problems totally solved due to clinical pharmacist recommendations were 69.57% (n=80). There was a significant increase in the occurrence of paleness (P=0.0001); urinary frequency (P=0.003); loss of appetite (P=0.0001), nausea (P=0.0001), vomiting (P=0.0001); and numbness (P=0.0001). A significant decrease in the occurrence and severity of chemotherapy-related adverse effects was observed as a mild urinary frequency (P=0.0001) and mild vomiting (P=0.0001) after the clinical pharmacist recommendations and provision of patient education. Results of this study revealed that diabetic cancer patients are definitly prone to the occurrence of drug-related problems and adverse drug reactions. Clinical pharmacist is expected to provide a well-defined education and care to those patients and the outcomes of pharmacist recommendations may diminish and prevent many drug-related problems and adverse drug reactions and by this, influence patients’ desire to complete the course of chemotherapy.

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Cite This Article

IZZETTİN, F. V., AL-TAİE, A., SANCAR, M., ALİUSTAOĞLU, M. (2017). Influence of Pharmacist Recommendations for Chemotherapy-Related Problems in Diabetic Cancer Patients. Marmara Pharmaceutical Journal, Cilt: 21 - Sayı: 3, 603–611. https://ajindex.com/articles/283663

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References (10)

  1. Vigneri P, Frasca F, Sciacca L, Pandini G, Vigneri R. Diabetes and cancer. Endocr Relat Cancer 2009;16:1103-23. Pharmaceutical Care Network Europe. DRP-Classification V6.2. 2010. http://www.pcne.org/upload/files/11_PCNE_ classification_V6.2.pdf. Accessed date: 8 March 2017.
  2. Ruths S, Viktil KK, Blix HS. Classification of drug-related problems. Tidsskr Nor Laegeforen 2007; 127: 3073-6.
  3. Leendertse AJ, Egberts AC, Stoker LJ, van den Bemt PM; HARM Study Group. Frequency of and risk factors for preventable medication-related hospital admissions in the Netherlands. Arch Intern Med 2008;168:1890-6.
  4. Stafford AC, Tenni PC, Peterson GM, Jackson SL, Hejlesen A, Villesen C, Rasmussen M. Drug-related problems identified in medication reviews by Australian pharmacists. Pharm World Sci 2009;31:216-23.
  5. Molokhia M, Tanna S, Bell D. Improving reporting of adverse drug reactions: Systematic review. Clin Epidemiol 2009;1:75- 92. Routledge PA, O’Mahony MS, Woodhouse KW. Adverse drug reactions in elderly patients. Br J Clin Pharmacol 2004;57:121- 6. Jamali AN, Aqil M, Alam MS, Pillai KK, Kapur P. A pharmacovigilance study on patients of bronchial asthma in a teaching hospital. J Pharm Bioallied Sci 2010;2:333-6.
  6. Ouyang Z, Peng D, Dhakal DP. Risk factors for hematological toxicity of chemotherapy for bone and soft tissue sarcoma. Oncol Lett 2013;5:1736-1740.
  7. Cosentino M, Leoni O, Oria C, Michielotto D, Massimo E, Lecchini S, Frigo G. Hospital-based survey of doctors’ attitudes to adverse drug reactions and perception of drug-related risk for adverse reaction occurrence. Pharmacoepidemiol Drug Saf 1999;8 Suppl 1:S27-35. van Grootheest K, de Jong-van den Berg L. Patients’ role in reporting adverse drug reactions. Expert Opin Drug Saf 2004;3:363-8.
  8. Aranda S, Jefford M, Yates P, Gough K, Seymour J, Francis P, Baravelli C, Breen S, Schofield P. Impact of a novel nurseled prechemotherapy education intervention (ChemoEd) on patient distress, symptom burden, and treatment-related information and support needs: results from a randomised, controlled trial. Ann Oncol 2012;23:222-31.
  9. Carelle N, Piotto E, Bellanger A, Germanaud J, Thuillier A, Khayat D. Changing patient perceptions of the side effects of cancer chemotherapy. Cancer 2002;95:155-63.
  10. Kayl AE, Meyers CA. Side-effects of chemotherapy and quality of life in ovarian and breast cancer patients. Curr Opin Obstet Gynecol 2006;18: 24-8. Hadder Akram AbdulRazzaq. Prediction of uncontrolled dyslipidemia of cardiac patients and the advers