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Journals / Medeniyet Medical Journal / 2018 / Cilt: 33 - Sayı: 2

Association between atrial fibrillation and red cell distribution width in patients with acute coronary syndrome

Akut koroner sendromlu hastalarda atriyal fibrilasyon ve eritrosit dağılım genişliği arasındaki ilişki

Sinan CERŞİT
Macit KALÇIK
Lütfi ÖCAL
Emrah Mehmet BAYAM
Pages
89–93
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

RDW is an inexpensive and readily available biomarker that may predict AF in patients with ACS.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cardiovascular disease is associated with red cell distribution width (RDW), an indicator of variability in circulating erythrocyte volume.
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Key Findings & Data:The inflammatory process in acute coronary syndrome (ACS) and atrial fibrillation (AF) may cause an increase in RDW.
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Conclusion & Impact:RDW is an inexpensive and readily available biomarker that may predict AF in patients with ACS.
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters

Abstract

Cardiovascular disease is associated with red cell distribution width (RDW), an indicator of variability in circulating erythrocyte volume. The inflammatory process in acute coronary syndrome (ACS) and atrial fibrillation (AF) may cause an increase in RDW. In this study, we purposed to investigate whether admission RDW is associated with AF in patients with ACS. This retrospective study included 50 patients with AF and 62 age- and sex- matched controls, who had presented with ACS between January 2016 to December 2017. All subjects had routine blood tests including common blood cell counts and also underwent physical examination and echocardiographic examination. Baseline characteristics were similar in the two groups. Left atrial (LA) diameter (47±13 vs 38±12 mm, p 11.7% predicted the presence of AF with a sensitivity of 56% and a specificity of 64% (AUC= 0.637, p<0.001). RDW is an inexpensive and readily available biomarker that may predict AF in patients with ACS.

Özet

Kardiyovasküler hastalıklar, kandaki eritrositlerin hacimlerindeki değişkenliğin göstergesi olan eritrosit dağılım genişliğinin (EDG) artışı ile ilişkilendirilmektedir. Enflamasyona bağlı olarak akut koroner sendrom (AKS) ve atriyal fibrilasyon (AF) gibi durumlar EDG’de artışa neden olabilir. Çalışmamızda, AKS ile hastaneye başvuran hastalardaki eşlik eden AF’nin EDG ile ilişkisini araştırdık. Ocak 2016-Aralık 2017 tarihleri arasındaki AKS ile başvuran AF mevcut olan 50 hasta ve, yaş ve cinsiyet yönünden eşleştirilmiş 62 kontrol hastası retrospektif olarak değerlendirildi. Tüm hastalara ayrıntılı fizik muayene ve ekokardiyografik görüntüleme uygulandı. Ayrıca, tam kan sayımını içeren rutin kan örnekleri alındı. Her iki grup arasında temel klinik özellikler benzerdi. Sol atriyal (SA) çap (47±13 ve 38±12 mm, p %11,7 olması AF varlığını %56 duyarlılık ve %64 özgüllük ile öngördü (EAA= 0,637, p<0,001). EDG ucuz ve kolay ulaşılabilir bir biyobelirteçtir. Yüksek EDG, AKS ile başvuran hastalarda AF varlığını öngörebilir.

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Cite This Article

CERŞİT, S., KALÇIK, M., ÖCAL, L., BAYAM, E. M. (2018). Association between atrial fibrillation and red cell distribution width in patients with acute coronary syndrome. Medeniyet Medical Journal, Cilt: 33 - Sayı: 2, 89–93. https://ajindex.com/articles/283321

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