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Journals / Medical Network Klinik Bilimler ve Doktor / 2003 / Cilt: 9 - Sayı: 4

Erythrocyte and plasma malondialdehyde levels in unstable angina pectoris followed in intensive care unit and stable angina pectoris

Yoğun bakım ünitesinde izlenen unstabil angina pektoriste ve stabil angina pektoriste eritrosit ve plazma malondialdehit düzeyleri

Pınar KAYA
Elmas ÖĞÜŞ
SABİYE AKBULUT
Ali Rıza ERBAY
Doğan YÜCEL
Hatice PAŞAOĞLU
Esin ÖZYILKAN
Pages
408–415
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

But there was no significant difference between SAP and USAP groups (p>0.05) Conclusion: Erythrocyte and plasma malondialdehyde levels increase as a result of lipid peroxidation in SAP and USAP.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The role of lipid peroxidation in ischemic heart diseases, such as acute myocardial infarction, stable angina pectoris, unstable angina pectoris and silent ischemia is known.
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Key Findings & Data:Material and Method: We studied 54 coronary artery disease patient, 28 of them were SAP and 26 of them were USAP.
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Conclusion & Impact:But there was no significant difference between SAP and USAP groups (p>0.05) Conclusion: Erythrocyte and plasma malondialdehyde levels increase as a result of lipid peroxidation in SAP and USAP.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anjina pektoris · Eritrositler · Yoğun bakım üniteleri

Abstract

Objective: The role of lipid peroxidation in ischemic heart diseases, such as acute myocardial infarction, stable angina pectoris, unstable angina pectoris and silent ischemia is known. In this study we aimed to determine the role of erythrocyte and plasma lipid peroxidation in stable angina pectoris (SAP) and unstable angina pectoris (USAP). Material and Method: We studied 54 coronary artery disease patient, 28 of them were SAP and 26 of them were USAP. For control group we choosed 20 patients who have no coronary artery disease, peripheric artery disease, hypertension, diabetes mellitus, obesity and smoking history. Plasma glucose, total cholesterol, triglyceride, LDL-cholesterol, HDL-cholesterol, malondialdehyde (MDA lipoprotein (a levels were determined in the study and control groups. Results: Erythrocyte and plasma malondialdehyde levels were significantly higher in SAP and USAP groups than control groups (p<0.05). But there was no significant difference between SAP and USAP groups (p>0.05) Conclusion: Erythrocyte and plasma malondialdehyde levels increase as a result of lipid peroxidation in SAP and USAP.

Özet

Amaç: Lipid peroksidasyonunun akut miyokard infarktüsü, stabil angina pektoris (SAP), unstabil angina pektoris (USAP) ve sessiz iskemi gibi iskemik kalp hastalıklarınındaki rolü bilinmektedir. Bu çalışmada, SAP ve USAP'ta eritrosit ve plazma lipid peroksidasyonunun rolünü araştırmayı amaçladık. Gereç ve Yöntem: Çalışmaya 28'i SAP ve 26'sı USAP olmak üzere 54 koroner arter hastası alındı. Kontrol grubu için koroner arter hastalığı, periferik damar hastalığı, hipertansiyon, diabetes mellitus, obezite bulunmayan ve sigara kullanmayan 20 kişi seçildi. Çalışma ve kontrol grubunda plazma glukoz, total kolesterol, trigliserid, LDL-kolesterol, HDL-kolesterol, malondialdehid (MDA), lipoprotein(a) değerlerine bakıldı. Bulgular: SAP ve USAP gruplarındaki eritrosit ve plazma malondialdehit düzeyinin kontrol grubuna göre anlamlı olarak daha fazla olduğu saptandı (p 0.05). Sonuç: SAP ve USAP'ta lipid peroksidasyonuna bağlı olarak eritrosit ve plazmada malondialdehit düzeyleri artmaktadır.

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Cite This Article

KAYA, P., ÖĞÜŞ, E., AKBULUT, S., ERBAY, A. R., YÜCEL, D., PAŞAOĞLU, H., ÖZYILKAN, E. (2003). Erythrocyte and plasma malondialdehyde levels in unstable angina pectoris followed in intensive care unit and stable angina pectoris. Medical Network Klinik Bilimler ve Doktor, Cilt: 9 - Sayı: 4, 408–415. https://ajindex.com/articles/279759

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