Journals / Medical Network Klinik Bilimler ve Doktor / 2000 / Cilt: 6 - Sayı: 4

The influence of hyperthyroidism and hypothyroidism on serum copper, zinc and magnesium levels

Hipertiroidizm ve hipotiroidizmin serum bakır, çinko ve magnezyum düzeylerine etkisi

Pages
431–434
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: Our results showed that there are significant decrease in patients with hyperthyroidism as compared with that of control.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:PURPOSE: Trace elements have extremely important function in metabolism; growth and tissue repairs and they are essential for life.
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Key Findings & Data:MATERIAL AND METHODS: The levels of copper, zinc and magnesium levels were determined by using Perkin-Elmer. 2380 atomic absorption spectrophotometer.
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Conclusion & Impact:CONCLUSION: Our results showed that there are significant decrease in patients with hyperthyroidism as compared with that of control.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hipertiroidi · Çinko · Magnezyum

Abstract

PURPOSE: Trace elements have extremely important function in metabolism; growth and tissue repairs and they are essential for life. Thyroid hormones have several effects on energy metabolism. In this study, we aimed to determinate the levels of sera Cu, Zn and Mg in-patients with hyperthyroidism and hypothyroidism. MATERIAL AND METHODS: The levels of copper, zinc and magnesium levels were determined by using Perkin-Elmer. 2380 atomic absorption spectrophotometer. RESULTS: The levels ofCu were found to be 88.91±9.92; 99.75±5.58; 102.25±8.18 /jgr./dl in case of hyperthyroid, hypothynoid and control, respectively. The levels ofZn were found to be 64.44±10.12; 90.75±7.30; 93.71±5.80 jugr. / dl in case of hyperthyroid, hyporthyroid and control, respectively. The levels of Mg were found, to be 19.46±1.76; 20.95±1.30; 20.89±1.34 mg/L in same groups, respectively. CONCLUSION: Our results showed that there are significant decrease in patients with hyperthyroidism as compared with that of control.

Özet

AMAÇ: Eser elementler büyüme, doku onarımı ve metabolik işlemler için gerekli olup, yaşam için temeldir. Tiroid hormonları başta enerji metabolizması olmak üzere birçok metabolik etkilere sahiptir. Bu nedenle çalışmamızda hipertiroidi ve hipotiroidili olgularda serum Cu, Zn ve Mg seviyelerinin ölçülmesi amaçlanmıştır. GEREÇ VE YÖNTEM: Serum bakır, çinko ve magnezyum düzeylerinin saptanmasında Perkin-Elmer 2380 atomik absorpsiyon spektrofotometresi kullanılmıştır. BULGULAR: Hipertiroidi, hipotiroidi ve kontrol grubunda serum Cu değerleri sırası ile 88.91±9.92; 99.75±5.58; 102.25±8.18 jıgr/dl olarak bulunmuştur. Serum Zn düzeyleri hipertiroidi, hipotiroidi ve kontrol grubunda sırası ile 64.44±10.12; 90.75±7.30; 93.71 ±5.80 fJ.gr/dl olarak saptanmıştır. Serum Mg düzeyleri ise aynı gruplarda yine sırası ile 19.46±1.76; 20.95±1.30; 20.89±1.34 mg/L olarak bulunmuştur. SONUÇ: Elde ettiğimiz sonuçlarımıza göre kontrol grubu ile karşılaştırıldığında hipertiroidizmli hastalarda bakır, çinko ve magnezyum konsantrasyonları azalmıştır.

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Cite This Article

TAMER, L., AKBAY, E., POLAT, G., BİLGİN, R., ATİK, U. (2000). The influence of hyperthyroidism and hypothyroidism on serum copper, zinc and magnesium levels. Medical Network Klinik Bilimler ve Doktor, Cilt: 6 - Sayı: 4, 431–434. https://ajindex.com/articles/278748

References (6)

  1. Chouapile M, Ryan JN, Zukosky CF: Effect on zinc on lipid peroxidation in liver microsomes and mitochondria. Proc Soc Exp Biol Med 1972; 141:150-153. 2. tsbir T, Tamer L, Erkişi M, Kekeç Y, Doran F, Varinli S, Taylor A: Copper. zinc and magnesium in serum and tissues from patients with carcinoma of breast, stomach and colon. Trace Elements and Electrolytes 1995; 12(3)113-115
  2. Delves HT: Assessments of trace elements status. Clin Endoc Metab 1985; 14:725-737
  3. Klevay ML: The role of copper, zinc and other chemical elements in man Developmental biology and genetic implication. Baca Ratan. CRC Press, 1984: 125-157
  4. Anderson SC, Cockayne S: Clinical Chemistry " Concept and Application" Nutritional Assessment: Macronutrients, Vitamins and Trace Elements in Rebecca Rettmen. Philadelphia. W.B. Saunders Company, 1993: 595-612
  5. Meisenberg G, Simmons W: The trace minerals in Medical Biochemistry. St. Lous, Missouri. Mosby Inc 1988: 500-508
  6. Butrimovitz GP, Purdy WC: The determination of zinc and copper in blood plasma by atomic absorption spectrophotometry. Anal Chem 1977; 63:94 8. Fernandez FJ, Kahn HL: Clinical methods for atomic absorption spectroscopy. Clin Chim Newsl 1971; 3:24 9. Saunders BD, Trapp RG: Association and prediction in basic and clinical bioistatistics. London Prentice Hall International inc. 1994. 10.Nishi Y, Kawate R, Usui T: Zinc metabolism in thyroid disease. Postgrad Med J 1980; 56(662):833-837. 11.Ahiara K, Nishi Y, Hatano S, Kihara M, Yoshimitsu K, Takeichi N, Ito T, Ezaki H, Usui T: Zinc, copper and selenium in thyroid disease. Am J Clin Nutrl984;40(l):26-35. 12.Buchinger W, Leopold B, Lind P, Langsteger W, Klima G, Koltringer P, Wawschinek O, Ober O: Changes in zinc levels in serum, whole blood and erythrocytes in disorders of thyroid function. Wien Klin Wochenschr 1988; 23(18): 619-621. 13.Dolev E, Deuster PA, Solomon B, Trostmann UH, Wartofsky L, Burman KD: Alterations in magnesium and zinc metabolism in thyroid disease. Metabolism 1988; 37(1): 61-67. 14.Sibutani Y, Yokota T, lijima S, Fujioka A, Katsuna S, Sakamoto K: Plasma and erythrocyte magnesium concentrations in thyroid disease: relation to thyroid function and the duration of illness. Jpn J Med 1989; 28(4):496-502. 15.Yoshido K, Kiso Y, Watanabe TK, Kaise K, Itagaki Y, Yamamoto M, Sakurada T, Yoshinaga K: Erythrocyte zinc in hyperthyroidism: reflection of integrated thyroid hormone levels over the previous few months. Metabolism 1990:39(2): 182-186. 16.Simsek G,