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Journals / Medical Network Klinik Bilimler ve Doktor / 2003 / Cilt: 9 - Sayı: 5

The effect of alfentanil on intraocular pressure following tracheal intubation

Trakeal entübasyonu takiben artan göz içi basıncına alfentanilin etkisi

Kenan KAYGUSUZ
Sinan GÜRSOY
Haydar ERDOĞAN
M. İlker TOKER
İBRAHİM HALUK KAFALI
Pages
577–580
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We concluded that the increase of IOP after trachéal intubation was prevented using alfentanil during induction.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we aimed to evaluate to effect of using alfentanil with anesthetic induction agents on intraocular pressure (IOP), after trachéal intubation Material and Method: Forty, elective nonophtalmic surgery patients were divided into 2 groups.
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Key Findings & Data:Alfentanil (Group A) and Placebo (Group P) patients were adminestered propofol 2mg/kg, vecuronium 0.1mg/kg intravenously.
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Conclusion & Impact:Conclusion: We concluded that the increase of IOP after trachéal intubation was prevented using alfentanil during induction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Alfentanil · Entübasyon · intratrakeal

Abstract

Objective: In this study, we aimed to evaluate to effect of using alfentanil with anesthetic induction agents on intraocular pressure (IOP), after trachéal intubation Material and Method: Forty, elective nonophtalmic surgery patients were divided into 2 groups. Alfentanil (Group A) and Placebo (Group P) patients were adminestered propofol 2mg/kg, vecuronium 0.1mg/kg intravenously. Alfentanil 20$\mu$g/kg was given in group A and saline in Group P after induction agents. Intraocular pressures were measured before induction (basal values), before intubation and at the 1st, 2nd, 5th min of intubation. In addition mean arterial pressure (MAP), heart rate (HR) and oxygen saturation (SpO2) were recorded. Results: All IOP values of the Group A were lower than basal IOP values. In Group P only the 5th min IOP values were lower than basal IOP value. While MAP measurments between basal values and all measurements were decreased in Group A, compared to basal MAP values, in group P MAP values were found decrease only the measurements were obtained after induction and 2nd and 5th minute of intubation. In group A patients heart rate measurements were found to decrease after induction and 5th minute of intubation. In group P 1st, 2nd and 5th minute measurments were found increased. Conclusion: We concluded that the increase of IOP after trachéal intubation was prevented using alfentanil during induction.

Özet

Amaç: Bu çalışmada anestezi indüksiyon ajanları ile birlikte uygulanan alfentanil veya salin'in trakeal entübasyon sonrası göz içi basınçta (GiB) yaptığı değişikliklerin incelenmesi amaçlandı. Gereç ve Yöntem: Elektif nonoftalmik cerrahi uygulanan 40 hasta alfentanil (Grup A) ve plasebo (Grup P) olmak üzere iki gruba ayrıldı. Her iki gruba propofol 2mg/kg, vekuronyum 0.1mg/kg dozunda indüksiyon için intravenöz olarak uygulandı. Grup A'ya anestezi indüksiyonunu takiben 20$\mu$g/kg alfentanil, Grup P'ye şalin uygulandı.Her iki grupta da GiB ölçümleri indüksiyondan önce (bazal değer), indüksiyondan sonra ve trakeal entübasyondan sonra l, 2. ve 5. dakikalarda yapıldı. Bu ölçümlerle eş zamanlı olarak ortalama arter basıncı (OAB), kalp hızı (KH) ve oksijen saturasyon (SpO2) değerleri kayıt edildi. Bulgular: GiB ölçümlerinde, Grup A'da bazal değerlere göre tüm ölçümlerde düşüş tespit edildi. Grup P'de ise sadece 5. dk da düşüş tespit edildi. OAB ölçümlerinde, Grup A'da bazal değerler ile tüm ölçümler arasında bir düşüş görülürken, Grup P'de indüksiyon sonrası ve entübasyon sonrası 2. ve 5. dk ölçümlerinde düşüş görüldü. KH ölçümlerinde, Grup A'da bazal değerlere göre indüksiyon sonrası ve 5. dk ölçümlerinde düşüş tespit edildi. Grup P'de ise entübasyon sonrası 1., 2. ve 5. dk ölçümlerinde artış görüldü. Sonuç: Trakeal entübasyonu takiben artan GİB'ının alfentanil ile önlenebileceği kanısındayız.

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Cite This Article

KAYGUSUZ, K., GÜRSOY, S., ERDOĞAN, H., TOKER, M. İ., KAFALI, İ. H. (2003). The effect of alfentanil on intraocular pressure following tracheal intubation. Medical Network Klinik Bilimler ve Doktor, Cilt: 9 - Sayı: 5, 577–580. https://ajindex.com/articles/278509

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