Journals / Journal of the Turkish-German Gynecological Association / 2008 / Cilt: 9 - Sayı: 2

HELLP sendromunda perinatal sonuçlar

Perinatal outcomes in HELLP syndrome

Pages
89–93
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Perinatal complications including IUGR, oligohydramniosis, fetal distress, Apgar score in first and fifth mins

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome is a severe complication of preeclampsia with high risk for mother and fetus.
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Key Findings & Data:Materials and Methods: Totally 64 pregnancies complicated by HELLP syndrome managed between January 1, 2000 and August 31, 2006 were reviewed.
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Conclusion & Impact:Perinatal complications including IUGR, oligohydramniosis, fetal distress, Apgar score in first and fifth mins
🔬Design:Review & Systematic Survey
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome is a severe complication of preeclampsia with high risk for mother and fetus. This study was conducted to evaluate the incidence of serious maternal and fetal morbidities and adverse outcomes in women with HELLP syndrome. Materials and Methods: Totally 64 pregnancies complicated by HELLP syndrome managed between January 1, 2000 and August 31, 2006 were reviewed. The demographic data, presenting signs and symptoms, and laboratory findings were evaluated. We recorded the adverse maternal outcomes including eclampsia, abruptio placenta, disseminated intravascular coagulopathy (DIC), acute renal failure (ARF), pulmonary complications, the need of mechanical ventilation, severe ascites, the need for transfusion, intracranial infarct or hemorrhage, and maternal death. Perinatal complications including IUGR, oligohydramniosis, fetal distress, Apgar score in first and fifth mins

Özet

AMAÇ: HELLP(hemolysis, elevated liver enzymes, and low platelet count: hemoliz, karaci¤er enzim yükselmesi ve düflük trombosit sayısı) sendromu, anne ve fetus için preeklampsinin ciddi bir komplikasyonudur. Bu çalışmada, HELLP sendromlu gebelerde ciddi maternal ve fetal morbidite ile komplikasyonların değerlendirilmesi amaçlandı. MATERYAL-METOD: Bu çalışmada 1 Ocak 2000 v e 31Ağustos 2006 tarihleri arasındaki toplam 64 HELLP sendromlu gebe incelendi. Demografik veriler, başvuru semptomları ve laboratuvar bulguları değerlendirildi. Eklampsi, ablasyo plasenta, dissemine intravasküler koagülopati (DİK), akut böbrek yetmezliği (ABY), pulmoner komplikasyonlar, mekanik ventilasyon ihtiyacı, ciddi asit, transfüzyon ihtiyacı, intrakraniyal infarkt ya da kanama ve maternal ölüm gibi maternal komplikasyonlar kaydedildi. İntrauterin gelişme geriliği oligohidroamniyoz, fetal distres, 1. ve 5. dakika Apgar skoru < 7, yenidoğan solunum sıkıntısı sendromu, sepsis, konvülziyon ve perinatal ölüm kaydedildi.BULGULAR: Gestasyonel yaşın 28 haftadan küçük olması tüm vakaların %21.9’unda görüldü. Kırk üç hasta ( %67.2) antenatal bakım almamıştı. ABY (25%), pulmoner komplikasyonlar (25%) ve eklampsi (23.4%) en sık görülen komplikasyonlardı. Toplam 64 HELLP sendromlu hastada beş maternal ölüm gözlendi. Maternal ölümlerin en sık nedeni multi organ yetmezliği idi. Bütün maternal ölümlerde trombosit sayısı 50.000 /µL’in altında idi. Fetal ve neonatal mortalite oranları ise %18.8 ve %20.3 idi. SONUÇ: HELLP sendromunda ciddi maternal ve fetal morbidite ve mortalite insidansı artmıştır. Bu yüzden HELLP sendromlu hastalarda erken tanı ve tedavi hayati önem taşımaktadır.

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Cite This Article

KAYGUSUZ, K., ÇETİN, A., GÜVENAL, T., GÖNÜLLÜ, M., KOL, Ö. İ., İMİR, G. A., ÇETİN, M. (2022). HELLP sendromunda perinatal sonuçlar. Journal of the Turkish-German Gynecological Association, Cilt: 9 - Sayı: 2, 89–93. https://ajindex.com/articles/567905

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