Journals / Medical Network Klinik Bilimler ve Doktor / 2003 / Cilt: 9 - Sayı: 2

Thyroid malignancy in hypoactive nodules in endemic nodular goitre

Endemik nodüler guatrlarda hipoaktif nodüllerin malignite açısından değerlendirilmesi

Pages
165–168
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In order to show the malignancy ratios of hypoactive nodules in endemic multinodular goiter we need larger patient series.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of the study was to present the epidemiology of thyroid cancers in hypoactive nodules in endemic multinodular goitres.
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Key Findings & Data:Material and Methods: The patients who underwent thyroid surgery in general surgery between April 2001 and May 2002 were evaluated.
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Conclusion & Impact:In order to show the malignancy ratios of hypoactive nodules in endemic multinodular goiter we need larger patient series.
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Guatr · nodüler · Guatr

Abstract

Objective: The aim of the study was to present the epidemiology of thyroid cancers in hypoactive nodules in endemic multinodular goitres. Material and Methods: The patients who underwent thyroid surgery in general surgery between April 2001 and May 2002 were evaluated. We performed fine-needle aspiration biopsy (FNAB) of cold nodules who had multinodular goitres. We perform a total lobectomy on the hypoactive nodule side with isthmectomy and a near total contralateral lobectomy on the other lobe and pathologic findings were evaluated. Results: In 32 (26 women, 6 men) of 79 patients who were treated surgically had hypoactive nodules. The female/male ratio was 3/1 (58/21) and the mean age was 43.57 (21-75). 36 patients (%46) had hyperthyroidism. The FNAB results of the patients who had hypoactive nodules were normal cytologic findings. In the pathologic evaluations of hypoactive nodules there was an occult papillary carcinoma. Conclusion: In the malignancy evaluation of hypoactive nodules in endemic multinodular goitre, fine needle aspiration biopsy has an important role but it's reliability can be discussed. In order to show the malignancy ratios of hypoactive nodules in endemic multinodular goiter we need larger patient series.

Özet

Amaç: Bu çalışma endemik nodüler guatrlarda hipoaktif tiroid nodüllerinin malignite oranlarını araştırmak amacı ile planlandı. Gereç ve Yöntem: Nisan 2001-Mayıs 2002 tarihleri arasında Genel Cerrahi Kliniği'nde tiroid cerrahisi uygulanan hastalar değerlendirildi. Multinodüler guatrı olan 30, soliter nodülü olan 2 hastadaki (26 kadın, 6 erkek) hipoaktif nodüllerden ince iğne aspirasyon biyopsisi yapıldı. Hastalara hipoaktif nodülün olduğu loba istmektomi ile birlikte total lobektomi, kontrlateral loba ise totale yakın lobektomi uygulandı ve histopatolojik bulgular değerlendirildi. Bulgular: Tiroid cerrahisi uygulanan 79 hastanın 32'sinde (26 kadın, 6 erkek) hipoaktif tiroid nodülü mevcuttu. Hastaların kadın/erkek oranı 3/1 (58/21) ve ortalama yaş 43.57 (21-75) olarak tespit edildi. 36 olguda (%46) hipertiroidi mevcuttu. İnce iğne aspirasyon biyopsilerinin sitolojik incelemelerinde malignite veya şüpheli bulgular saptanmadı. Cerrahi rezeksiyon sonucunda histopatolojik değerlendirmelerde hipoaktif nodüllerden birinde okült papiller karsinom tespit edildi. Sonuç: Endemik multinodüler guatrlardaki hipoaktif nodüllerin malignite açısından değerlendirilmesinde tiroid ince iğne aspirasyon biyopsisi önemli bir yere sahip olmakla birlikte güvenilirliği tartışılabilir. Endemik multinoduler guatrlardaki hipoaktif nodüllerin malignite oranlarını daha sağlıklı olarak ortaya koyabilmek için daha geniş hasta serilerine ihtiyaç vardır.

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Cite This Article

ACUN, Z., UÇAN, B., CİHAN, A., ULUKENT, S. C., CÖMERT, M., CESUR, A. (2003). Thyroid malignancy in hypoactive nodules in endemic nodular goitre. Medical Network Klinik Bilimler ve Doktor, Cilt: 9 - Sayı: 2, 165–168. https://ajindex.com/articles/278496

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