SavedAdd your journal

Journals / Medical Network Klinik Bilimler ve Doktor / 2005 / Cilt: 11 - Sayı: 2

Placental angiogenesis

Plasenta damarlarının oluşumu

Zeynep ÇABUK
MEHMET ALİ ONUR
MEHMET SİNAN BEKSAÇ
Pages
217–224
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, placentation and its angiogenesis, and some common factors playing role in this process like VEGF (Vascular endothelial growth factor), angiopoiteins, PlGF (Placental-like growth factor), PDGF (Platelet-derived growth factor) and LIF (Leukemia inhibiting factor) and their expressions in pathologic conditions will be explained.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Defects in placentation during pregnancy may affect the growth of the fetus negatively resulting abortion and fetal death.
📊
Key Findings & Data:Because of this reason, trends in placental investigations have been rising upon placenta development and placental vessel development.
💡
Conclusion & Impact:In this review, placentation and its angiogenesis, and some common factors playing role in this process like VEGF (Vascular endothelial growth factor), angiopoiteins, PlGF (Placental-like growth factor), PDGF (Platelet-derived growth factor) and LIF (Leukemia inhibiting factor) and their expressions in pathologic conditions will be explained.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Vasküler endoteliyal büyüme faktör A · Plasenta · Plasenta hastalıkları

Abstract

Defects in placentation during pregnancy may affect the growth of the fetus negatively resulting abortion and fetal death. Because of this reason, trends in placental investigations have been rising upon placenta development and placental vessel development. In this review, placentation and its angiogenesis, and some common factors playing role in this process like VEGF (Vascular endothelial growth factor), angiopoiteins, PlGF (Placental-like growth factor), PDGF (Platelet-derived growth factor) and LIF (Leukemia inhibiting factor) and their expressions in pathologic conditions will be explained.

Özet

Hamilelik döneminde, plasenta oluşumu sırasında meydana gelebilecek herhangi bir aksaklık fetusun gelişmesini olumsuz etkilemekte hatta düşük ve fetal ölümlere neden olmaktadır. Bu nedenle plasenta ile ilgili çalışmalar plasenta gelişimi ve plasenta damarlarının oluşum mekanizmalarını aydınlatma yönünde hız kazanmıştır. Bu derlemede, plasenta ve damarlarının oluşumunu, bu oluşum sırasında rol alan VEGF (Vascular endothelial growth factor), angiopoiteinler, PlGF (Placental-like growth factor), PDGF (Platelet-derived growth factor) ve LIF (Leukemia inhibiting factor) gibi faktörler ve bunların patolojik durumlarda ifadelerindeki değişiklikler anlatılacaktır.

🔖

Cite This Article

ÇABUK, Z., ONUR, M. A., BEKSAÇ, M. S. (2005). Placental angiogenesis. Medical Network Klinik Bilimler ve Doktor, Cilt: 11 - Sayı: 2, 217–224. https://ajindex.com/articles/278359

References (16)

  1. Kingdom J, Huppertz B, Seaward G, Kaufmann P Development of the placenta villous tree and its concequences for fetal growth. European Journal of Obstetrics & Cynecology and Reproductive Biology 2000; 92:35-43
  2. Ahmed A, Dunk C, Ahmad S, Khaliq A. Regulation of Placental Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PIGF) and Soluable Flt-1 by Oxygen-A Review. Placenta 2000; 21, Supplement A, Trophoblast Research, 2000; 14:16-24
  3. Charnock-Jones DS, Burton GJ. Placental vascular morphogenesis. Bailliere's Clinical Obstetrics and Gynaecology 2000'14:953-68
  4. Sherer DM, Abulafia O. Angiogenesis during Implantation, and Placental and Early Embryonic Development. Placenta 2001; 22:1-13
  5. Cross JC, Hemberger M, Lu Y, Nozaki T, Whiteley K, Masutani M, Adamson SL. Trophoblast functions, angiogenesis and remodelling of the maternal vasculature in the placenta. Molecular and Cellular Endocrinology 2002; 187:207-12
  6. Aşan E, Kaymaz FF, Çakar N, Dağdeviren A, Beksaç MS. Vasculogenesis in early human placental villi: an ultrastructural study. Annals of Anatomy 1999; 181:549-54
  7. Ribatti D, Vacca A, Nico B, Roncali L, Dammacco F. Postnatal vasculogenesis. Mechanisms of Development 2001; 100:157-63
  8. Bussolino F, Albini A, Camussi G, Presta M, Viglietto G, Ziche M, Persico G. Role of Soluable Mediators in Angiogenesis. European Journal of Cancer 1996; 32:2401-12
  9. Liekens S, DeClercq E, NeytsJ. Angiogenesis: regulators and clinical applications. Biochemical Pharmacology 2001; 61:253-70
  10. Brooks PC. Role of Integrins in Angiogenesis. European Journal of Cancer 1996; 32:2423-9
  11. Ellis LM, Fidler IJ. Angiogenesis and Metastasis. European Journal of Cancer 1996; 32:2451-60. 12.Clauss M. Functions of the VEGF Receptor-1 (Flt-1) in the Vasculature. Trends Cardiovasc Med 1998; 8:241-5
  12. Underwood PA, Bean PA, Gamble JR. Rate of endothelial expansion is controlled by cellrcell adhesion. The International Journal of Biochemistry & Cell Biology 2002; 34:55-69
  13. Ferrara N. Vascular Endothelial Growth Factor. European Journal of Cancer 1996; 32:2413-22
  14. Tucker GC. Inhibitors of Integrins. Current Opinion in Pharmacology 2002; 2:394-402
  15. Eliceiri BP, Cheresh DA. Adhesion events in angiogenesis. Current Opinion in Cell Biology 2001; 13:563-8
  16. Charnock-Jones D.S, Kaufmann P, Mayhev T.M. Aspects of Human Fetoplacental Vasculogenesis and Angiogenesis. Placenta 2003; 00 1-11.(Basımda) 18.0ng S, Lash G, Baker PN. Angiogenes