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Journals / Meme Sağlığı Dergisi / 2007 / Cilt: 3 - Sayı: 3

The importance of sentinel lymph node biopsy in early invasive breast cancer: Experıence of 3. general surgery department in Lutfı Kırdar Kartal education and research hospital

Erken evre meme kanserinde sadece mavi boya klavuzluğunda yapılan sentinel lenf nodu biyopsisinin yeri: Dr. Lütfi Kırdar Kartal eğitim ve araştırma hastanesi 3. cerrahi kliniği’nin geçerlilik çalışması

Mehmet ESER
LEVENT KAPTANOĞLU
Hasan Ediz SIKAR
Hasan Fehmi KÜÇÜK
Cengiz Volkan MENTEŞ
Fırat TUTAL
Hüseyin UZUN
Necmi KURT
Pages
131–135
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Axillary dissections can be avoided through sentinel lymph nodes without metastasis.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: Sentinel lymph node biopsy is a minimal invasive technique, which is an alternative for axillary dissection.
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Key Findings & Data:MATERIAL and METHOD: 40 patients without axillary metastasis were included in our study.
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Conclusion & Impact:Axillary dissections can be avoided through sentinel lymph nodes without metastasis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kanserin erken teşhisi · İleriye dönük çalışma · Sonuçların tekrarlanabilirliği

Abstract

AIM: Sentinel lymph node biopsy is a minimal invasive technique, which is an alternative for axillary dissection. In this prospective study we tried to evaluate accuracy of sentinel lymph node biopsy in early stage breast cancer, using only isosulphane blue solution. MATERIAL and METHOD: 40 patients without axillary metastasis were included in our study. Age, diagnostic biopsies, preoperative stage, time and number of sentinel lymph node biopsies, histopathological evaluations, postoperative stage, early postoperative complications were evaluated. RESULTS: Mean detection time for sentinel lymph nodes was 15 (5-25) minutes by 38 patients. Mean number for detected nodes was 1 (1-4). We found mean 16 (9-30) nodes with axillary dissections. 19 patients had axillary metastasis. Only a single patient showed negative sentinel lymph node result. By 37 patients we have shown that sentinel lymph node biopsy is a reliable method. We could not detect any recurrences or metastasis. CONCLUSION: Sentinel lymph node biopsy is a reliable method in evaluation of axillary node status. Axillary dissections can be avoided through sentinel lymph nodes without metastasis.

Özet

AMAÇ: Sentinel lenf nodu biyopsisi (SLNB) erken evre meme kanserinde aksiller lenf nodu diseksiyonuna (ALND) alternatif olarak kabul edilen minimal invaziv bir tekniktir. Bu prospektif çalışmada sadece mavi boya (Patent Blue Viole ) kullanılarak erken evre meme kanserinde sentinel lenf nodu biyopsisinin geçerliliğini araştırmayı amaçladık. GEREÇ ve YÖNTEM: Klinik olarak aksillası negatif olan ardışık 40 hasta çalışmaya alındı.Tüm hastalarda yaş, tanısal amaçlı biyopsi, preoperatif evre, SLN bulma süresi ve sayısı, SLN ve ALND’nun histopatolojik sonuçları, postoperatif evre, erken postoperatif komplikasyonlar tespit edildi. SLN saptama oranı, yanlış negatiflik ve tanısal kesinlik hesaplandı. BULGULAR: Hastaların 38’inde (%95) ortanca 15 dakikada (aralık 5-25) SLN saptandı. Çıkarılan SLN ortanca sayısı 1 (aralık 1-4) idi. ALND ile ortanca 16 (aralık 9-30 ) lenf nodu çıkarıldı ve 19 hastada aksilla pozitifliği saptandı. Bu hastaların 1’inde (%5,3) SLN negatifti ve serimizde yöntemin başarısız olduğu tek olgu buydu. Diğer 18 hastanın 7’sinde (%39) SLN haricinde çıkarılan diğer lenf nodlarında tümör tutulumu yoktu. SLN saptanabilen 38 hastanın 37’sinde SLN aksillanın metastatik durumunu doğru olarak yansıtıyordu ve tanısal kesinlik oranı %97 olarak hesaplandı. En uzun takip edilen hasta 32 ay, en kısa takip edilen hasta 7 aydır. Hiçbir hastada nüks veya metastaz tespit edilmedi. SONUÇ: Erken evre meme kanserinde, sadece mavi boya kullanarak yapılan SLNB’de, SLN’da metastaz saptanmazsa, kabul edilebilir bir yanlış negatiflik oranı da göze alarak ALND yapılmayabilir.

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Cite This Article

ESER, M., KAPTANOĞLU, L., SIKAR, H. E., KÜÇÜK, H. F., MENTEŞ, C. V., TUTAL, F., UZUN, H., KURT, N. (2007). The importance of sentinel lymph node biopsy in early invasive breast cancer: Experıence of 3. general surgery department in Lutfı Kırdar Kartal education and research hospital. Meme Sağlığı Dergisi, Cilt: 3 - Sayı: 3, 131–135. https://ajindex.com/articles/278313

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