Journals / Meme Sağlığı Dergisi / 2009 / Cilt: 5 - Sayı: 1

Idiopathic granulomatous mastitis mimicing breast cancer - a case report

Meme kanserini taklit eden idiyopatik granülomatöz mastit

Pages
40–43
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Despite the two-week-convenient medical therapy, the clinical findings revealed no improvement.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Idiopathic granulomatous mastitis (IGM) is a rare benign disease of the breast with an unknown etiology, which mimicks the carcinoma of the breast.
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Key Findings & Data:Its shows an increased incidence among women of the breeding ages usually developing in a single breast as an isolated lesion, clinically revealing dermal findings similar to the inflammatory carcinoma of the breast.
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Conclusion & Impact:Despite the two-week-convenient medical therapy, the clinical findings revealed no improvement.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erişkin · Meme neoplazmları · Tanı

Abstract

Idiopathic granulomatous mastitis (IGM) is a rare benign disease of the breast with an unknown etiology, which mimicks the carcinoma of the breast. Its shows an increased incidence among women of the breeding ages usually developing in a single breast as an isolated lesion, clinically revealing dermal findings similar to the inflammatory carcinoma of the breast. Radiologically, the differential diagnosis between IGM and cancer remains to be a challenge for the physicians. Histopathologic examinations reveal intense inflammation accompanied by non-caseified granulomas constituting the characteristic features of this disease. The presence of other etiologies associated with histopathologic findings of granulomatous reactions must be excluded to achieve the diagnosis of IGM. A thirty five years old female patient admitted to our clinic with complaints of an erythematous tender mass, which she had realized to be present in her right breast for the last fifteen days. Despite the two-week-convenient medical therapy, the clinical findings revealed no improvement. Since the diagnostic procedures could not exclude malignancy, surgery was performed. Following resection, the specimen was evaluated histopathologically revealing the diagnosis of granulomatous mastitis. No evidences of recurrence were met in the postoperative sixth month. This case is presented to emphasize that the possibility of IGM should be kept in mind as an entity for differential diagnosis during the clinical evalutions of women of the breeding ages admitting with complaints of isolated breast masses that bring up the suspicion of breast cancer either clinically, or radiologically.

Özet

İdiyopatik granülomatöz mastit (İGM); memenin nadir görülen, etyolojisi bilinmeyen, klinik ve radyolojik olarak meme kanserini taklit edebilen benign bir hastalığıdır. Sıklıkla doğurganlık çağındaki kadınlarda, tek memede ve klinik olarak inflamatuar karsinomu taklit edebilen cilt bulgularının eşlik edebildiği, izole meme kitlesi şeklinde ortaya çıkar. Radyolojik olarak kanserden ayırt edimesi güçlük arzeder. Histopatolojik incelemede yoğun inflamatuar reaksiyon ile beraber hastalığın karakteristik özelliği olan non-kazeifiye granülomlar görülür. İdiyopatik granülomatöz mastit tanısının konulabilmesi için, histopatolojik olarak granülomatöz reaksiyon yapabilen diğer etyolojilerin var olmadığının gösterilmesi gereklidir. Otuzbeş yaşında kadın hasta, 15 gün önce sağ memesinde farkettiği kızarıklık, ağrı ve ele gelen kitle şikayeti ile başvurdu. İki haftalık antibiyotik ve antienflamatuar tedavi sonrası klinik bulgularda değişiklik saptanmaması üzerine yapılan ileri incelemelerde karsinom tanısının ekarte edilememesi üzerine genişletilmiş kitle eksizyonu ameliyatı yapıldı. Histopatolojik incelemede granülomatöz mastit tanısı konuldu. Takiplerinin 6. ayında olan hastada nüks hastalık gelişmedi. Olgu; nadir görülmesi, doğurganlık çağında izole meme kitlesi ile başvuran, klinik ve radyolojik olarak meme kanseri düşünülen kadınlarda, ayırıcı tanıda granülomatöz mastit olasılığının da akılda bulundurulması gerektiğini vurgulamak için sunulmuştur.

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Cite This Article

ALTINTOPRAK, F., BAYTEKİN, H. F., ALTINAY, A. E., EREN, T. T. (2009). Idiopathic granulomatous mastitis mimicing breast cancer - a case report. Meme Sağlığı Dergisi, Cilt: 5 - Sayı: 1, 40–43. https://ajindex.com/articles/278197

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