Journals / Meme Sağlığı Dergisi / 2009 / Cilt: 5 - Sayı: 2

Positron emission tomography (PET) in breast cancer diagnosis

Meme kanseri tanısında pozitron emisyon tomografisi (PET)

Pages
69–72
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review the benefits of PET in the diagnosis of breast cancer and its methods are reported

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Breast cancer is the most frequent cancer in women and is the second lethal malignancy after lung cancer.
📊
Key Findings & Data:Screening mammography is widely used for its diagnosis, but it has a considerably high false negativity rate.
💡
Conclusion & Impact:In this review the benefits of PET in the diagnosis of breast cancer and its methods are reported
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Kanserin erken teşhisi · Meme neoplazmları · Tanı

Abstract

Breast cancer is the most frequent cancer in women and is the second lethal malignancy after lung cancer. Screening mammography is widely used for its diagnosis, but it has a considerably high false negativity rate. Various factors has effects on the sensitivity of mammography and its specificity is low. MRI and ultrasonography are complementary methods for the difficult cases but there is still need for determining the benign or malignant nature of the breast masses. In this respect, nuclear medicine extended its useful contributions by scintimammography after the use of specific substances such as Tc-99m MIBI and further improved with the Positron Emission Tomography. In this review the benefits of PET in the diagnosis of breast cancer and its methods are reported

Özet

Meme kanseri kadınlarda en sık görülen kanser türü olup akciğer kanserinden sonra ikinci önde gelen ölüm nedenidir. Tanısında tarama mamografisi kullanımı yaygındır ancak yanlış negatiflik oranı oldukça yüksektir. Mammografinin duyarlılığı birçok faktörden etkilenir ve özgüllüğü de düşüktür. MRI ve ultrason zor vakalarda başvurulan tamamlayıcı yöntemler olmakla beraber memedeki kitlelerin benign, malign ayırımını yapabilmek için daha duyarlı yöntemlere gereksinim vardır. Nükleer tıp bu alanda Tc-99m MIBI gibi daha spesifik maddeleri kullanarak başlattığı yararlı katkıları, SPECT Sintimammografi ile sürdürerek Pozitron Emisyon Tomografisi kullanımı ile daha da geliştirmiştir. Bu derlemede meme kanserinin tanısında PET kullanımının sağladığı yararlar ve kullanım yöntemleri anlatılmaktadır.

🔖

Cite This Article

SAYMAN, H. B. (2009). Positron emission tomography (PET) in breast cancer diagnosis. Meme Sağlığı Dergisi, Cilt: 5 - Sayı: 2, 69–72. https://ajindex.com/articles/278179

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Hendricks J. The frequency and consequences of false negative mammograms. Eur J Cancer. 2000;36(suppl 5):S44. Abstract 9
  2. Rosenberg RD; Hunt WC; Williamson MR; Gilliland FD; Wiest PW; Kelsey CA; Key CR; Linver MN Radiology. 1998; 209(2):511-8
  3. Hoh Ck, Hawkins RA, Glaspy JA, et al. Cancer detection with whole body PET using 2-(18-F) fluoro-2-deoxy-d-glucose. JCAT 1993;17:582-9
  4. Hawkins RA,Hoh CK. PET FDG studies in Oncology. Nucl Med Biol1994;21:739-47
  5. Isidoro A, Casado E, Redondo A, Acebo P, Espinosa E, Alonso A M, Cejas P, Hardisson D, Vara J A F, Belda-Iniesta C, González-Barón M, Cuezva J M. Breast carcinomas fulfill the Warburg hypothesis and provide metabolic markers of cancer prognosis. Carcinogenesis 2005; 26(12):2095-2104
  6. McDonough M D, DePeri E R, Mincey B A. The role of positron emission tomographic imaging in breast cancer. Volume 6, Number 1 / February, 2004
  7. Nieweg O E, Kim E E, Wong W, Broussard W F, Singletery S E, Hortobagyi G N, Tilbury R S. Positron Emission Tomography with Fluorine- 18- Deoxyglucose in the Detection and Staging of Breast Cancer. Cancer 1993, Volume 71, Issue 12 (p 3920-3925
  8. FDG Positron Emission Tomography-Breast Cancer, #CAG-00094A, Decision Memorandum, Washington DC: CMS; Feb 28, 2002
  9. Cho D, Ahn B, Lee S, et al. Assessment of bone metastasis in breast cancer: comparison between F-18 FDG PET-CT and Tc-99m MDP bone scan. Program and Abstracts of the Society of Nuclear Medicine 54th Annual Meeting; June 3-6, 2007; Washington, DC. Abstract 1575. J Nucl Med. 2007;48(Suppl 2):368P
  10. Yap CS, et al. JNM, 2001 Sep;42(9):1334-7 11) Eubank WB et al. Sem Nucl Med. 2005 Apr;35(2):84-99 12) Rajendran, J.G. (2006) Hypoxia imaging-directed radiation treatment planning. European Journal of Nuclear Medicine and Molecular Imaging 33(s1).