SavedAdd your journal

Journals / Medicine Science / 2018 / Cilt: 7 - Sayı: 4

Prevalence of microscopic colitis in patients with chronic diarrhea

Gokhan PEKTAS
Meral SOYLU SÖZEN
Ayhan VURMAZ
Osman ERSOY
Pages
841–844
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although there is no general consensus about the localization and number of intestinal biopsies, a large number of biopsies should be collected, even from the colon mucosa with normal macroscopic appearance in these patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Microscopic colitis affects nearly 10% of the patients with chronic diarrhea which is defined as an increase in the number of daily defecation or the amount of stool lasting more than 4 weeks.
📊
Key Findings & Data:This is a retrospective review of 54 patients (31 men and 23 women) with chronic diarrhea who were admitted to the gastroenterology department of the study center between July 2009 and July 2010.
💡
Conclusion & Impact:Although there is no general consensus about the localization and number of intestinal biopsies, a large number of biopsies should be collected, even from the colon mucosa with normal macroscopic appearance in these patients.
🔬Design:Review & Systematic Survey
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Özet

Microscopic colitis affects nearly 10% of the patients with chronic diarrhea which is defined as an increase in the number of daily defecation or the amount of stool lasting more than 4 weeks. The present study aims to analyze the Prevalence of Microscopic Colitis in patients who have admitted to a tertiary health center due to chronic diarrhea with unidentified etiology. This is a retrospective review of 54 patients (31 men and 23 women) with chronic diarrhea who were admitted to the gastroenterology department of the study center between July 2009 and July 2010. Data related with the patient age, patient gender, laboratory findings and histopathological alterations were obtained from hospital files. The men and women included in this study were statistically similar with respect to their mean age (36.4 ±11.1 years vs 43.1 ±18.0 years, p=0.125). The male and female patients with cheronic diarrhea had statistically similar incidences of duodenitis (8/31 vs 11/23, 25.8% vs 47.8%, p=0.097). These men and women had also statistically similar incidences of terminal ileitis (10/31 vs 8/23, 32.3% vs 34.8%, p=0.847) respectively. The male and female patients with chronic diarrhea had statistically similar incidences of non-specific colitis (19/31 vs 12/23, 61.3% vs 52.2%, p=0.499). However, non-specific colitis was significantly more frequent in patients with normal duodenum biopsy than patients with duodenitis (24/35, 68.6% vs 7/19, 36.8%; p=0.008). Microscopic colitis should be considered in differential diagnosis of middle aged and elderly women with chronic diarrhea. Although there is no general consensus about the localization and number of intestinal biopsies, a large number of biopsies should be collected, even from the colon mucosa with normal macroscopic appearance in these patients.

🔖

Cite This Article

PEKTAS, G., SÖZEN, M. S., VURMAZ, A., ERSOY, O. (2018). Prevalence of microscopic colitis in patients with chronic diarrhea. Medicine Science, Cilt: 7 - Sayı: 4, 841–844. https://ajindex.com/articles/277637

References (12)

  1. Datta I, Brar SS, Andrews CN, et al. Microscopic colitis: a review for the surgical endoscopist. Can J Surg. 2009;52:E167-72. Read NW, Krejs GJ, Read MG, et al. Chronic diarrhea of unknown origin. Gastroenterol. 1980;78:264-71.
  2. Okamoto R, Negi M, Tomii S, et al. Diagnosis and treatment of microscopic colitis. Clin J Gastroenterol. 2016;9:169-74.
  3. Stoicescu A, Becheanu G, Dumbrava M, et al. Microscopic colitis-a missed diagnosis in diarrhea-predominant irritable bowel syndrome. J Clin Med. 2012;71:3-9.
  4. Misra V, Misra SP, Dwivedi M, et al. Microscopic colitis in patients presenting with chronic diarrhea. Indian J Pathol Microbiol. 2010;53:15-9.
  5. Gentile NM, Khanna S, Loftus EV, et al. The epidemiology of microscopic colitis in Olmsted County from 2002 to 2010: a population-based study. Clin Gastroenterol Hepatol. 2014;12:838-42.
  6. Erdem L, Yıldırım S, Akbayır N, et al. Prevalence of microscopic colitis in patients with diarrhea of unknown etiology in Turkey. World J Gastroenterol. 2008;14:4319-23. Ianiro G1, Cammarota G, Valerio L, et al. Microscopic colitis. World J Gastroenterol. 2012;18:6206-15. Storr MA. Microscopic colitis: epidemiology, pathophysiology, diagnosis and current management-an update 2013. ISRN Gastroenterol. 2013;2013: 352718. Thomas PD1, Forbes A, Green J, Guidelines for the investigation of chronic diarrhoea, Gut. 2003;52:1-15.
  7. Nhylin N, Bohr J, Eriksson S, et al. Systematic review: microscopic colitis. Aliment Pharmacol Ther. 2006;23:1525-34.
  8. Netzer P, Levkovits H, Zimmermann A, et al. Collagen colitis and lymphocytic (microscopic) colitis: different or common origin? Z Gastroenterol. 1997;35:681-90.
  9. Raclot G, Queneau PE, Ottignon Y. Incidence of collagenous colitis. A retrospective study in the east of France. Gastroenterol. 1994;106:A23. Rajan J, Noble C, Anderson C, et al. The epidemiology and clinical features of collagenous colitis in Lothian. Gut. 2005;54:A99. Heron T, Walsh S, Mowat A. Microscopic colitis in tayside: clinical features, associations, and behaviour. Gut. 2005;54: A84. Burch VC, Price SK, Wright JP, et al. Collagenous colitis-a rare cause of chronic watery diarrhoea. A case report. S Afr Med J. 1992;81:617-9.
  10. Narita T, Akiyama M. Collagenous colitis in a Japanese patient. Pathol Int. 1996;46:211-5.
  11. Valle Mansilla JL, Leon Barua R, Recavarren Arce S, et al. Microscopic colitis in patients with chronic diarrhea. Rev Gastroenterol Peru. 2002;22:275-8.
  12. Tagkalidis PP, Gibson PR, Bhathal PS. Microscopic colitis demonstrates a