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Journals / Medicine Science / 2018 / Cilt: 7 - Sayı: 4

Can neutrophil-lymphocyte ratio be a predictor of cerebral vasospasm in patients with subarachnoid hemorrhage?

Hüseyin Ulaş PINAR
Enes DUMAN
Süleyman DENİZ
İlker COVEN
Ömer KARACA
Rafi DOĞAN
Pages
766–768
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion NLR can be used as an independent predictor of vasospasm development as a cheap and practical method, along with other predictive factors.

📌 3 Key Takeaways

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Objective & Hypothesis:This study aimed to investigate the relationship between neutrophil-lymphocyte ratio (NLR) and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (SAH).
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Key Findings & Data:Materials and Methods The study was performed by retrospectively analyzing the data of 170 aneurysmal SAH patients who admitted to the intensive care unit of our hospital between 2011 and 2017.
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Conclusion & Impact:Conclusion NLR can be used as an independent predictor of vasospasm development as a cheap and practical method, along with other predictive factors.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Özet

This study aimed to investigate the relationship between neutrophil-lymphocyte ratio (NLR) and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (SAH). Materials and Methods The study was performed by retrospectively analyzing the data of 170 aneurysmal SAH patients who admitted to the intensive care unit of our hospital between 2011 and 2017. We investigated the ability of NLR values calculated from the blood samples taken at the time of admission to predict for vasospasm. Results Thirty-five percent of the patients developed vasospasm. NLR values were associated with the development of vasospasm (OR 1.15; 95% confidence interval, 1.09-1.22; p<0.0001). When the ability of NLR to predict for vasospasm was analyzed, the area under curve (AUC) of ROC curve was 0.776 (95% confidence interval: 0.70-0.85). The optimal cut-off point was 14.48 using the Youden index. The sensitivity and specificity for this cut-off point were 61.7% and 83.6%, respectively. Conclusion NLR can be used as an independent predictor of vasospasm development as a cheap and practical method, along with other predictive factors.

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Cite This Article

PINAR, H. U., DUMAN, E., DENİZ, S., COVEN, İ., KARACA, Ö., DOĞAN, R. (2018). Can neutrophil-lymphocyte ratio be a predictor of cerebral vasospasm in patients with subarachnoid hemorrhage?. Medicine Science, Cilt: 7 - Sayı: 4, 766–768. https://ajindex.com/articles/277610

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References (9)

  1. Karimi RJ, Choudry O, Prestigiacomo CJ. Intra-arterial pharmacotherapy of cerebral vasospasm. In: Prestigiacomo CJ and Bendok BR (eds) Endovascular Surgical Neuroradiology: Theory and Clinical Practice. New York, USA: Thieme. 2015, pp 210-217.
  2. Zheng J, Cai J, Li H, Zeng K, He L, Fu H, Zhang J, Chen L, Yao J, Zhang Y, Yang Y, Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio as prognostic predictors for hepatocellular carcinoma patients with various treatments: a meta-analysis and review. Cell Physiol Biochem. 2017;44(3):967-81.
  3. Cataudella E, Giraffa C. M, Di Marca S, Pulvirenti A, Alaimo S, Pisano M, Terranova V, Corriere, T., Ronsisvalle M. L, Di Quattro R, Stancanelli B, Giordano M, Vancheri C, Malatino L. Neutrophil-To-Lymphocyte ratio: An emerging marker predicting prognosis in elderly adults with community- acquired pneumonia. J Am Geriatr Soc. 2017;65(8):1796-801.
  4. Chao-Hui Dong, Zhang-Min Wang, Si-Yu Chen, Neutrophil to lymphocyte ratio predict mortality and major adverse cardiac events in acute coronary syndrome: A systematic review and meta-analysis, Clin Biochem. 2018;52:131-6.
  5. Wang F, Hu S, Ding Y, Ju X, Wang L, Lu Q, Wu X. Neutrophil-to- lymphocyte ratio and 30-Day mortality in patients with acute intracerebral hemorrhage. J Stroke Cerebrovasc Dis. 2016;25(1):182-7.
  6. Zhang J, Cai L, Song Y, Shan B, He M, Ren Q, Chen C, Liu Z, Zeng Y, Xu J. Prognostic role of neutrophil lymphocyte ratio in patients with intracerebral hemorrhage. Oncotarget. 2017;8(44):7752-60
  7. Tao C, Wang J, Hu X, Ma J, Li H, You C. Clinical value of neutrophil to lymphocyte and platelet to lymphocyte ratio after aneurismal subarachnoid hemorrhage. Neurocrit Care. 2017;26(3):393-401.
  8. Eryiğit U, Cakmak VA, Şahin A, Tatlı O, Paslı S, Gazioğlu G, Karaca Y. The diagnostic value of the neutrophil-lymphocyte ratio in distinguishing between subarachnoid hemorrhage and migraine. Am J Emerg Med. 2017;35(9):127680. Rothoerl RD, Axmann C, Pina AL, Woertgen C, Brawanski A. Possible role of the C-reactive protein and white blood cell count in the pathogenesis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg Anesthesiol. 2006;18:68-72.
  9. Tam AK, Ilodigwe D, Mocco J, Mayer S, Kassell N, Ruefenacht D, Schmiedek P, Weidauer S, Pasqualin A, Macdonald RL. Impact of systemic inflammatory response syndrome on vasospasm, cerebral infarction, and outcome after subarachnoid hemorrhage: exploratory analysis of CONSCIOUS-1 database. Neurocritic Care. 2010;13:182-9