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Journals / Medicine Science / 2017 / Cilt: 6 - Sayı: 3

Effects of age, gender, BMI, settlement and smoking on lead and cadmium accumulation in heart tissue

Aybike DİP
Servet Birgin IRİTAS
Görkem MERGEN
Ahmet Hakan DİNÇ
Tülin SÖYLEMEZOĞLU
Pages
531–536
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Significant increase Cd level were observed in smokers’ heart tissues (p<0.05), however, contrary to expectations, Pb has no statistically significant result

📌 3 Key Takeaways

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Objective & Hypothesis:Cadmium (Cd) and lead (Pb) are well-known risk factors for peripheral arterial and some other cardiovascular diseases.
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Key Findings & Data:Heart tissues of the 112 autopsy cases, representing a sample set of population living in capital city of Turkey: Ankara Province (both in city center and suburban), were collected from Turkey Ministry of Justice, Council of Forensic Medicine in Ankara Branch.
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Conclusion & Impact:Significant increase Cd level were observed in smokers’ heart tissues (p<0.05), however, contrary to expectations, Pb has no statistically significant result
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Cadmium (Cd) and lead (Pb) are well-known risk factors for peripheral arterial and some other cardiovascular diseases. The aim of the study was to determine the level of both toxic metals, in the human heart tissue and compare the accumulation to their age, gender, body mass index, living environment and smoking habit. Heart tissues of the 112 autopsy cases, representing a sample set of population living in capital city of Turkey: Ankara Province (both in city center and suburban), were collected from Turkey Ministry of Justice, Council of Forensic Medicine in Ankara Branch. Lead and cadmium analysis was carried out by Graphite Furnace Atomic Spectrometry technique. Cd/Pb results and individuals’ information were assessed by SPSS statistically. Average value of Pb was found as 1374.99±237.01ppb and Cd was found as 287.54±66.43ppb in all heart tissue samples. Consideration of metal levels in autopsy heart tissues by age, statistically significant positive correlation in Cd was observed (p<0.05). There was no correlation found between metal levels with gender and BMI values. Both Pb and Cd levels of the samples who lived in urban was significantly greater than in suburban areas (p<0.05). Significant increase Cd level were observed in smokers’ heart tissues (p<0.05), however, contrary to expectations, Pb has no statistically significant result

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Cite This Article

DİP, A., IRİTAS, S. B., MERGEN, G., DİNÇ, A. H., SÖYLEMEZOĞLU, T. (2017). Effects of age, gender, BMI, settlement and smoking on lead and cadmium accumulation in heart tissue. Medicine Science, Cilt: 6 - Sayı: 3, 531–536. https://ajindex.com/articles/277410

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