SavedAdd your journal

Journals / Medicine Science / 2018 / Cilt: 7 - Sayı: 1

Evaluation of serum heavy metal levels on primary ovarian insufficiency

Şule ÖZER
Ayla AKTULAY
Osman AYKUT
Hikmet Gülşen UNCU
Hatice KANSU ÇELİK
Sunullah SOYSAL
MEHMET ÇINAR
Yaprak ENGİN ÜSTÜN
Pages
39–42
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Identifying people with elevated blood heavy metal levels will give chance of avoiding oncoming destructive health effects of heavy metals.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study we aimed to investigate the level of exposure to these toxic heavy metals such as Aluminum (Al), Arsenic (As), Mercury (Hg) ,Manganese (Mn) and Lead (Pb) among Premature Ovarian Insufficiency (POI) patients.
📊
Key Findings & Data:This cross-sectional study was performed in 23 women with normal reproductive hormones (control) and 23 women with POI (case).
💡
Conclusion & Impact:Identifying people with elevated blood heavy metal levels will give chance of avoiding oncoming destructive health effects of heavy metals.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

In this study we aimed to investigate the level of exposure to these toxic heavy metals such as Aluminum (Al), Arsenic (As), Mercury (Hg) ,Manganese (Mn) and Lead (Pb) among Premature Ovarian Insufficiency (POI) patients. This cross-sectional study was performed in 23 women with normal reproductive hormones (control) and 23 women with POI (case). Risk factors evaluated were; age,body mass index(BMI), gravidity and blood serum metal levels (Al,As,Hg,Mn,Pb). Risk factors were compared between groups. Women with history of pelvic surgery, any cancer or autoimmune disease treatment, endometriosis and other chronic systemic diseases were excluded from the study. The Age, BMI and Gravidity were similar between the case and control group (p > 0.05). And also the aluminum, arsenic, manganese, mercury and lead serum levels were smilar between the case and control group (p > 0.05). Etiology of most POI cases remains undetermined. Early recognition of predisposing factors of POI may help to make prevention about ovarian failure and would offer this patient population the opportunity to preserve fertility. Identifying people with elevated blood heavy metal levels will give chance of avoiding oncoming destructive health effects of heavy metals.

🔖

Cite This Article

ÖZER, Ş., AKTULAY, A., AYKUT, O., UNCU, H. G., ÇELİK, H. K., SOYSAL, S., ÇINAR, M., ÜSTÜN, Y. E. (2018). Evaluation of serum heavy metal levels on primary ovarian insufficiency. Medicine Science, Cilt: 7 - Sayı: 1, 39–42. https://ajindex.com/articles/277254

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Rebar RW. Premature ovarian “failure” in the adolescent. Ann N Y Acad Sci. 2008;1135:138-45. European Society for Human Reproduction and Embryology (ESHRE) Guideline Group on POI, Webber L, Davies M, Anderson R, Bartlett J, Braat D, Cartwright B, Cifkova R, de Muinck Keizer-Schrama S, Hogervorst E, Janse F, Liao L, Vlaisavljevic V, Zillikens C, Vermeulen N. ESHRE Guideline: management of women with premature ovarian insufficiency. Hum Reprod. 2016;31(5):926-37.
  2. Rock JA, Rosenwaks Z, Adashi EY, Jones HW Jr, King TM. Microsurgery for tubal reconstruction following Falope-Ring sterilization in swine. J Microsurg. 1979;1(1):61-4.
  3. Gleicher N, Weghofer A, Barad DH. Defining ovarian reserve to better understand ovarian aging. Reprod Biol Endocrinol. 2011;9:23. Soave I, Lo Monte G, Marci R, POI: Premature Ovarian Insufficiency/ Pregnancy or Infertility? N Am J Med Sci. 2013;5(1):71. Tokmak A, Yıldırım G, Sarıkaya E, Çınar M, Boğdaycıoğlu N, Yılmaz FM, Yılmaz N. Increased oxidative stress markers may be a promising indicator of risk for primary ovarian insufficiency: a cross-sectional case control study. Rev Bras Ginecol Obstet. 2015;37(9):411-6. Practice Committee of the American Society for Reproductive Medicine. Testing and interpreting measures of ovarian reserve: a committee opinion. Fertil Steril. 2015;103(3):e9-e17. Ozkaya E, Baser E, Cinar M, Korkmaz V, Kucukozkan T. Does diurnal rhythm have an impact on fetal biophysical profile? J Matern Fetal Neonatal Med. 2012;25(4):335-8.
  4. Shestakova IG, Radzinsky VE, Khamoshina MB. Occult form of premature ovarian insufficiency. Gynecol Endocrinol. 2016;32(sup2):30-2.
  5. Haschek H, Porpaczy P. Therapeutic and toxicologic problems in the therapy of nonspecific urinary tract infections with impaired kidney function. Wien Klin Wochenschr. 1968;80(42):769-76.
  6. Tan SY, Praveena SM, Abidin EZ, Cheema MS. A review of heavy metals in indoor dust and its human health-risk implications. Rev Environ Health. 2016;31(4):447-56.
  7. Chiang WF, Yang HJ, Lung SC, Huang S, Chiu CY, Liu IL, Tsai CL, Kuo CY. A comparison of elementary schoolchildren’s exposure to arsenic and lead. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2008;26(3):237-55.
  8. Kang Y, Cheung KC, Wong MH. Wong, Mutagenicity, genotoxicity and carcinogenic risk assessment of indoor dust from three major cities around the Pearl River Delta. Environ Int. 2011;37(3):637-43.
  9. Li T, Wan Y, Ben Y, Fan S, Hu J. Relative importance of different exposure routes of heavy metals for