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Journals / Medicine Science / 2019 / Cilt: 8 - Sayı: 4

Is vitamin D an important factor in hepatosteatosis in childhood obesity?

Elif OZSU
Derya ACAR TEPE
Pages
908–912
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, in this study, no association was observed between 25-hydroxy vitamin D deficiency and hepatosteatosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Childhood obesity is one of the most serious public health problems with obesity-related complications such as hepatosteatosis or type 2 diabetes occurring during early childhood.
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Key Findings & Data:The aim of this study was to examine the relationship between 25-hydroxy vitamin D levels and obesity with hepatosteatosis (HS) in children. 128 obese children participated in this study.
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Conclusion & Impact:However, in this study, no association was observed between 25-hydroxy vitamin D deficiency and hepatosteatosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Childhood obesity is one of the most serious public health problems with obesity-related complications such as hepatosteatosis or type 2 diabetes occurring during early childhood. The aim of this study was to examine the relationship between 25-hydroxy vitamin D levels and obesity with hepatosteatosis (HS) in children. 128 obese children participated in this study. Hepatosteatosis was diagnosed and graded using ultrasonography in all patients. Serum levels of 25-hydroxy vitamin D, calcium, phosphate, alkaline phosphatase (ALP), parathormone (PTH), lipid, glucose and insulin were also measured. The data was analyzed across two groups of obese children – those with hepatosteatosis and those without hepatosteatosis. Forty-two percent of the study group were male. The mean age of the subjects was 12.1±3.1 years (range 4-18 years). Hepatosteatosis was identified in 39% of children (n: 50). A high prevalence (122/128 cases, 95%) of either 25-hydroxy vitamin D deficiency or insufficiency was determined. However, there was no statistically significant association between 25-hydroxy vitamin D levels and hepatosteatosis. Uric acid, alanine aminotransferase (ALT) and triglyceride levels were significantly higher in the HS group compared to non-HS group. There is a high prevalence of 25-hydroxy vitamin D deficiency and insufficiency among children with hepatosteatosis. However, in this study, no association was observed between 25-hydroxy vitamin D deficiency and hepatosteatosis.

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Cite This Article

OZSU, E., TEPE, D. A. (2019). Is vitamin D an important factor in hepatosteatosis in childhood obesity?. Medicine Science, Cilt: 8 - Sayı: 4, 908–912. https://ajindex.com/articles/277166

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