Journals / Medicine Science / 2019 / Cilt: 8 - Sayı: 4

Evaluation of left ventricular functions before and after iron therapy in patients with iron deficiency anemia

Pages
947–952
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

STE might be useful both for early identification of LV subclinical impairment in patients with IDA and also improvement in myocardial deformation indices after iron therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of present study is to evaluate left ventricular (LV) functions using speckle tracking echocardiography (STE) after iron therapy in patients with iron deficiency anemia (IDA).
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Key Findings & Data:We consecutively enrolled 92 patients with IDA who needed iron therapy and 82 age- and gender-matched healthy volunteers in our study.
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Conclusion & Impact:STE might be useful both for early identification of LV subclinical impairment in patients with IDA and also improvement in myocardial deformation indices after iron therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

The aim of present study is to evaluate left ventricular (LV) functions using speckle tracking echocardiography (STE) after iron therapy in patients with iron deficiency anemia (IDA). We consecutively enrolled 92 patients with IDA who needed iron therapy and 82 age- and gender-matched healthy volunteers in our study. Their clinical, laboratory, conventional two-dimensional echocardiography (2DE), and STE examinations were performed to all patients before and after iron therapy. Echocardiographic measurements were compared with healthy controls. The hemoglobin level increased after iron therapy (7.2±2.9 vs. 12.1±2.0, p<0.001). There was no statistically difference in conventional echocardiographic measurements of patients before and after iron therapy. The LV global longitudinal strain (GLS: 19.3±4.0 vs. 23.2±3.6, p<0.001), but it was still statistically lower than the LV GLS of the healthy controls (23.2±3.6 vs. 25.9±3.1, p<0.001). The LV global systolic strain rate increased after iron therapy (1.7±0.1 vs. 2.2±0.3, p<0.03). IDA might be associated with impairment in LV longitudinal myocardial function. STE might be useful both for early identification of LV subclinical impairment in patients with IDA and also improvement in myocardial deformation indices after iron therapy.

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Cite This Article

KANAR, B. G., HARAS, A. B., MENGUC, M. U., GOL, G., MUTLU, B. (2019). Evaluation of left ventricular functions before and after iron therapy in patients with iron deficiency anemia. Medicine Science, Cilt: 8 - Sayı: 4, 947–952. https://ajindex.com/articles/277037

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References (8)

  1. DeLoughery TG. Iron deficiency anemia. Med Clin North Am. 2017;101:31932.
  2. Lopez A, Cacoub P, Macdougall IC, et al. Iron deficiency anaemia. Lancet. 2016;387:907-16.
  3. Lozoff B, Beard J, Connor J, Barbara F, et al. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev. 2006;64:34-43.
  4. Das I, Saha K, Mukhopadhyay D, et al. Impact of iron deficiency anemia on cell-mediated and humoral immunity in children: A case control study. J Nat Sci Biol Med. 2014;5:158-63.
  5. Pereira AA, Sarnak MJ. Anemia as a risk factor for cardiovascular disease. Kidney Int Suppl. 2003;87:S32-9. Sarnak MJ, Tighiouart H, Manjunath G, et al. Anemia as a risk factor for cardiovascular disease in the atherosclerosis risk in communities (ARIC) study. J Am Coll Cardiol. 2002;40:27-33. Mitchell JE. Emerging role of anemia in heart failure. Am J Cardiol. 2007;99:15-20. Sullivan JL. Iron therapy and cardiovascular disease. Kidney Int Suppl. 1999;69:135-7. Chengode S. Left ventricular global systolic function assessment by echocardiography. Ann Card Anaesth. 2016;19:26-34.
  6. Cameli M, Mondillo S, Galderisi M, et al. Speckle tracking echocardiography: a practical guide. G Ital Cardiol (Rome). 2017;18:253-69.
  7. Collier P, Phelan D, Klein A. A Test in context: myocardial strain measured by speckle-tracking echocardiography. J Am Coll Cardiol. 2017;69:1043-56. Comité Nacional de Hematología. Iron deficiency anemia. Guideline for diagnosis and treatment. Arch Argent Pediatr. 2009;107:353-61.
  8. Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American society of echocardiography and the european association of cardiovascular imaging. Eur Heart J Cardiovasc Imaging. 2015;16:233-70. 14. Nagueh SF, Smiseth OA, Appleton CP, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American society of echocardiography and the european association of cardiovascular imaging. Eur Heart J Cardiovasc Imaging. 2016;17:1321-60. 15. Mądry W, Karolczak MA. Physiological basis in the assessment of myocardial mechanics using speckle-tracking echocardiography 2D. Part I. J Ultrason. 2016;16:135-44. 16. Voigt JU, Pedrizzetti G, Lysyansky P, et al. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. J Am Soc Echocardiogr. 2015;28:183-93