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Journals / Medicine Science / 2020 / Cilt: 9 - Sayı: 4

1800MHz Radiofrequency electromagnetic radiation: Does it affect heat shock genes expression levels in the rat brain?

Badel ARSLAN
Nurcan ARAS
Gül YAŞ
Ayşegül ÇETİNKAYA
Pages
929–934
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These changes may lead to neurobiological deficits in prolonged exposure

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The brain could recognizethe cell phone radiation as environmental stress and may alter stress-related gene expression levels.
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Key Findings & Data:We investigated whether exposure to 1800MHz Radiofrequency Electromagnetic Radiation (RF-EMR) recognize the expression levels of some HSPs (Cryaa, Crybb, Hsp20, Hsp25, Hsp70) in mature rat’s brain tissue.
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Conclusion & Impact:These changes may lead to neurobiological deficits in prolonged exposure
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

The brain could recognizethe cell phone radiation as environmental stress and may alter stress-related gene expression levels. Heat shock proteins (HSP) are a family of proteins that are produced by cells in response to the exposure of stressful conditions. We investigated whether exposure to 1800MHz Radiofrequency Electromagnetic Radiation (RF-EMR) recognize the expression levels of some HSPs (Cryaa, Crybb, Hsp20, Hsp25, Hsp70) in mature rat’s brain tissue. The experimental group was exposed to 1.800MHz RF-EMR in restrainer for eight weeks with 2 h/day. The specific absorption rate (SAR) was 0.06 W/kg. The sham group was kept in restrainer but not exposed to radiation. The Control group was kept under their condition. Whole brain was homogenized.ViA7 Real-Time-PCR software was used to measure CT values of the genes and ΔΔCT values were also calculated. Cryaa (p=0.02), Crybb (p=0.01), and Hsp20 (p<0.001) genes expression levels were decreased in the exposed group according to the sham and control group. However, Hsp25 (p=0.069) and Hsp70 (p=0.329) genes expression levels were not altered. The brain can recognize RF-EMR as a stress factor and alter some HSPs levels in brain tissue. These changes may lead to neurobiological deficits in prolonged exposure

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Cite This Article

ARSLAN, B., ARAS, N., YAŞ, G., ÇETİNKAYA, A. (2020). 1800MHz Radiofrequency electromagnetic radiation: Does it affect heat shock genes expression levels in the rat brain?. Medicine Science, Cilt: 9 - Sayı: 4, 929–934. https://ajindex.com/articles/276922

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