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Journals / Medicine Science / 2020 / Cilt: 9 - Sayı: 1

The effect of gestational hypertension on the maternal mean platelet volume

Emre BASER
Funda SALGUR
Melek BİLGE
Safak OZDEMİRCİ
Eylem UNLUBİLGİN
Ozlem Moraloglu TEKİN
Deniz ESİNLER
Aykan YUCEL
Pages
90–93
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, further studies are needed to examine the predictive value of MPV in the progression of the hypertensive diseases of pregnancy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:To evaluate the effect of gestational hypertension on the maternal mean platelet volume (MPV).
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Key Findings & Data:MPVs were calculated within 24 hours in the intrapar-tum period.
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Conclusion & Impact:However, further studies are needed to examine the predictive value of MPV in the progression of the hypertensive diseases of pregnancy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

To evaluate the effect of gestational hypertension on the maternal mean platelet volume (MPV). The study group comprised pregnant women with gestational hypertension who gave birth to single, term, healthy fetuses and control group was pregnant women without any complications. MPVs were calculated within 24 hours in the intrapar-tum period. The mean MPV of 68 hypertensive and randomly selected 135 normotensive pregnant women were compared. The MPV of gestational hypertensive group was significantly higher (9.5±0.98 vs 9.2±0.9 fL; p=0.015). Using ROC analysis, the optimal MPV cut off value was found 9.25 fL with the sensitivity of 60.0% and the specificity of 61.0% (AUC=0.622, 95% CI=0.538-0.707, p=0.004) for the prediction of gestational hypertension. This study demonstrated that maternal MPV cannot be used to predict gestational hypertension in clinical practice due to its low sensitivity and specificity. However, further studies are needed to examine the predictive value of MPV in the progression of the hypertensive diseases of pregnancy.

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Cite This Article

BASER, E., SALGUR, F., BİLGE, M., OZDEMİRCİ, S., UNLUBİLGİN, E., TEKİN, O. M., ESİNLER, D., YUCEL, A. (2020). The effect of gestational hypertension on the maternal mean platelet volume. Medicine Science, Cilt: 9 - Sayı: 1, 90–93. https://ajindex.com/articles/276860

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References (15)

  1. Chen KH, Seow KM, Chen LR. Progression of gestational hypertension to pre-eclampsia: A cohort study of 20,103 pregnancies. Pregnancy Hypertens. 2017;10:230-37
  2. Yoder SR, Thornburg LL, Bisognano JD. Hypertension in pregnancy and women of childbearing age. Am J Med. 2009;122:890-5
  3. Buchbinder A, Sibai BM, Caritis S, et al. Adverse perinatal outcomes are significantly higher in severe gestational hypertension than in mild preeclampsia. Am J Obstet Gynecol. 2002;186:66-71
  4. Saudan P, Brown MA, Buddle ML, et al. Does gestational hypertension become pre-eclampsia? Br J Obstet Gynaecol. 1998;105:1177-84
  5. Van Oostwaard MF, Langenveld J, Schuit E, et al. Recurrence of hypertensive disorders of pregnancy: an individual patient data metaanalysis. Am J Obstet Gynecol. 2015;212:1-17
  6. Kumru P, Aka N, Kose G, et al. The Value of Mean Platelet Volume in Predicting The Severity of Preeclampsia and of Hellp Syndrome. Obstet Gynaecol Reprod Med. 2007;13:9-13
  7. Ceyhan T, Beyan C, Baser I, et al. The effect of pre-eclampsia on complete blood count, platelet count and mean platelet volume. Ann Hematol. 2006; 85:320-2
  8. Ozdemir S GH, Acar A, Celik C, et al. The Comprasion of Maternal and Fetal Outcomes Pregnancies of Complicated by Moderate to Severe Thrombocytopenia Caused by Gestational Thrombocytopenia Preeclampsia/HELLP Syndrome and Immune Thrombocytopenic Purpura. Obstet Gynaecol Reprod Med. 2008;14:154-8
  9. Delmis J. Hypertension in pregnancy. Lijec Vjesn. 2006;128:357-68
  10. Ozdemirci S, Baser E, Kasapoglu T, et al. Predictivity of mean platelet volume in severe preeclamptic women. Hypertens Pregnancy. 2016;35:474-82
  11. Han L, Liu X, Li H, et al. Blood coagulation parameters and platelet indices: changes in normal and preeclamptic pregnancies and predictive values for preeclampsia. PloS one. 2014;9:114488
  12. Kashanian M, Hajjaran M, Khatami E, et al. Evaluation of the value of the first and third trimester maternal mean platelet volume (MPV) for prediction of pre-eclampsia. Pregnancy hypertension. 2013;3:222-6
  13. Dogan K, Guraslan H, Senturk MB, et al. Can Platelet Count and Platelet Indices Predict the Risk and the Prognosis of Preeclampsia? Hypertens Pregnancy. 2015;34:434-42
  14. Dundar O, Yoruk P, Tutuncu L, et al. Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsia. Prenat Diagn. 2008;28:1052-6
  15. Kanat-Pektas M, Yesildager U, Tuncer N, et al. Could mean platelet