Mucocillary clearance in patients with septal deviation

Objective & Hypothesis:Objectives: We investigated mucociliary clearance (MC) time before and after surgery in patients with nasal obstruction due to septal deviation.

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Key Findings & Data:Patients and Methods: Mucociliary clearance was measured with the use of the saccharin test in 32 patients (10 females, 22 males; mean age 25 years; range 18 to 41 years) with nasal obstruction due to nasal septal deviation and in a control group of 30 healthy volunteers (13 females, 17 males; mean age 28 years; range 18 to 45 years) without nasal obstruction.

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Conclusion & Impact:Conclusion: Our results showed that MC time is prolonged after septal surgery.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Hava yolu tıkanıklığı · Siliyer motilite bozuklukları · Mukosiliyer klirens

Abstract

Objectives: We investigated mucociliary clearance (MC) time before and after surgery in patients with nasal obstruction due to septal deviation. Patients and Methods: Mucociliary clearance was measured with the use of the saccharin test in 32 patients (10 females, 22 males; mean age 25 years; range 18 to 41 years) with nasal obstruction due to nasal septal deviation and in a control group of 30 healthy volunteers (13 females, 17 males; mean age 28 years; range 18 to 45 years) without nasal obstruction. The tests were performed a day before and three months after the operation in the patient group. Resultsrffis mean lengths of MC were 9.5±1 min and 13±1 min in the patient group before and after surgery, respectively, and 11.5±0.6 min in the control group. No significant differences were found between the control and patient groups (p>0.05). However, compared to the pre-surgery level, the mean MC time significantly increased after surgery in the patient group (p<0.01). Conclusion: Our results showed that MC time is prolonged after septal surgery. Considering the effect of intranasal interventions on the duration of MC, it is recommended that surgery-associated injuries should be kept to minimum.

Özet

Amaç: Septum deviyasyonuna bağlı burun tıkanıklığı olan olgularda, ameliyat öncesi ve sonrası mukosiliyer klirens (MK) süresi araştırıldı. Hastalar ve Yöntemler: Septum deviyasyonuna bağlı burun tıkanıklığı olan 32 hasta (10 kadın, 22 erkek; ort. yaş 25; dağılım 18-41) ile burun tıkanıklığı olmayan 30 gönüllüde (13 kadın, 17 erkek; ort. yaş 29; dağılım 18-45) MK süreleri sakkarin testiyle ölçüldü. Hasta grubu ölçümleri ameliyattan bir gün önce ve üç ay sonra yapıldı. Bulgular: Hasta grubunda ortalama MK süresi ameliyat öncesinde 9.5±1 dakika, ameliyat sonrasında 13±1 dakika; kontrol grubunda 11.5±0.6 dakika bulundu. Kontrol grubu ile ameliyat öncesi ve sonrası MK süreleri arasında anlamlı farklılık saptanmadı (p>0.05). Septum deviyasyonu olan olguların ameliyat sonrası MK sürelerinin anlamlı derecede uzadığı gözlendi (p<0.01). Sonuç: Bulgularımız septal cerrahi sonrasında MK süresinin uzadığını gösterdi. Burun içi girişimlerin MK süresini uzattığı bilinmeli; bu girişimler sırasında mukozaya verilecek zarar en düşük düzeyde tutulmalıdır.

Keywords

Hava yolu tıkanıklığı Siliyer motilite bozuklukları Mukosiliyer klirens Burun mukozası Nazal septum Burun tıkanıklığı Airway Obstruction Ciliary Motility Disorders Mucociliary Clearance Nasal Mucosa Nasal Septum Nasal Obstruction

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Cite This Article

KIZILAY, A., AKARÇAY, M., MİMAN, M. C., ÖZTURAN, O., ÇOKKESER, Y., ERDEM, T. (2003). Mucocillary clearance in patients with septal deviation. Kulak Burun Boğaz Klinikleri, Cilt: 5 - Sayı: 2, 79–82. https://ajindex.com/articles/274524

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