Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2017 / Cilt: 23 - Sayı: 6

Investigation of Oxidative Stress Index and Lipid Profile in Cattle with Brucellosis

Brusellozisli Sığırlarda Oksidatif Stres İndeksi ve Lipid Profilinin İncelenmesi

Pages
933–937
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These data may contribute to the diagnosis of the disease and especially to the determination of inflammation severity.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to define the oxidative-antioxidative capacity and lipid profile in cattle with brucellosis.
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Key Findings & Data:A total of 32 cattle of Simmental breed were used in the study, among those, 22 demonstrated microbiologically positive for brucellosis while 10 were negative.
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Conclusion & Impact:These data may contribute to the diagnosis of the disease and especially to the determination of inflammation severity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to define the oxidative-antioxidative capacity and lipid profile in cattle with brucellosis. A total of 32 cattle of Simmental breed were used in the study, among those, 22 demonstrated microbiologically positive for brucellosis while 10 were negative. Biochemical analysis included total oxidant capacity (TOC), total antioxidant capacity (TAC), oxidative stress index (OSI), triglyceride (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), very low-density lipoprotein-cholesterol (VLDL-C) and low-density lipoprotein-cholesterol (LDL-C). TAC value was found to be statistically significantly lower (P=0.007), and TOC and OSI values were found to be significantly higher [respectively (P=0.013) and (P=0.002)] in cattle with brucellosis compared to the control group. TC (P=0.012) and LDL-C (P=0.0004) values were significantly increased, and TG (P=0.004), HDL-C (P=0.023) and VLDL-C (P=0.004) values were significantly decreased compared to the control group. As a conclusion, it was determined that Brucella infection leads to important changes in the oxidative-antioxidative capacity and lipid profile in cattle. These data may contribute to the diagnosis of the disease and especially to the determination of inflammation severity.

Özet

Bu çalışmanın amacı, brusellozisli sığırlarda oksidatif-antioksidatif kapasite ve lipid profilinin belirlenmesidir. Çalışmada mikrobiyolojik analiz sonrası brusellozis tespit edilen 22 ve negatif olan 10, toplamda 32 Simental ırkı inek kullanıldı. Biyokimyasal olarak total oksidan kapasite (TOK), total antioksidan kapasite (TAK), oksidatif stres indeksi (OSİ), trigliserid (TG), total kolesterol (TC), yüksek yoğunluklu lipoproteinkolesterol (HDL-C), çok düşük yoğunluklu lipoprotein-kolesterol (VLDL-C) ve düşük yoğunluklu lipoprotein-kolesterol (LDL-C) değerleri belirlendi. Brusellozisli sığırlar ile kontrol grubu karşılaştırıldığında TAK değerinin istatiksel olarak anlamlı bir şekilde düştüğü (P=0.007), TOK ve OSİ değerlerinin ise istatistiksel olarak anlamlı bir şekilde artmış olduğu, [sırasıyla (P=0.013) ve (P=0.002)] tespit edildi. Yine TC (P=0.012) ve LDL-C (P=0.0004) değerlerinin kontrol grubuna göre istatistiksel olarak anlamlı arttığı, TG (P=0.004), HDL-C (P=0.023) ve VLDL-C (P=0.004) değerlerinin istatistiksel olarak azalmış olduğu belirlendi. Sonuç olarak, brusella enfeksiyonunun sığırlarda oksidatif-antioksidatif kapasitede ve lipit profilinde önemli değişikliklere neden olduğu belirlendi. Elde edilen bu bulgular özellikle hastalıktaki yangı şiddetinin belirlenmesine ve diagnozuna katkıda bulunabilir.

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Cite This Article

MERHAN, O., BOZUKLUHAN, K., KURU, M., BÜYÜK, F., ÖZDEN, Ö., KÜKÜRT, A. (2017). Investigation of Oxidative Stress Index and Lipid Profile in Cattle with Brucellosis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 23 - Sayı: 6, 933–937. https://ajindex.com/articles/273591

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