Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2007 / Cilt: 13 - Sayı: 2

Disseminated intravascular coagulation (DIC)

Dissemine intravasküler koagulasyon (DIC).

Pages
215–222
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also, therapy must be directed depending on the nature of DIC, age, etiology of DIC, site and severity of hemorrhage or thrombosis, and hemodynamic and other clinical parameters.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Disseminated intravascular coagulation (DIC) is a complex acquired coagulopathy resulting from excessive thrombin formation.
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Key Findings & Data:Abnormal tissue factor is a major mechanism initiating DIC in many disorders.
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Conclusion & Impact:Also, therapy must be directed depending on the nature of DIC, age, etiology of DIC, site and severity of hemorrhage or thrombosis, and hemodynamic and other clinical parameters.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:prognoz · hayvan hastalıkları · yaygın damar içi pıhtılaşma

Abstract

Disseminated intravascular coagulation (DIC) is a complex acquired coagulopathy resulting from excessive thrombin formation. Abnormal tissue factor is a major mechanism initiating DIC in many disorders. Clinical symptoms such as predominant bleeding, thromboembolic complications or organ failure should be evaluated together with the profile of laboratory test results. Numerous laboratory tests are available to monitor DIC. The guiding principle of therapy is to identify and vigorously treat the underlying cause of DIC without delay. Treatment options to correct the hemostatic defect and to dampen the intravascular clotting/fibrinolytic process include transfusion of blood product, heparin, antithrombin III (ATIII), and antifibrinolytic agents. Also, therapy must be directed depending on the nature of DIC, age, etiology of DIC, site and severity of hemorrhage or thrombosis, and hemodynamic and other clinical parameters.

Özet

Dissemine intravasküler koagulasyon (DIC) aşırı trombin oluşumuyla sonuçlanan kompleks edinsel bir koagulopatidir. Anormal doku faktörü birçok bozuklukta DIC’i başlatan en önemli mekanizmadır. Predominant kanama, tromboembolik komplikasyonlar veya organ yetersizliği gibi klinik belirtiler, laboratuvar test sonuçları profili ile birlikte değerlendirilir. DIC’i teşhis etmek için birçok laboratuvar testi mevcuttur. Tedavide prensip, DIC’e neden olan primer hastalığı identifiye etmek, hemostatik defekti düzeltmek ve kan ürünleri, heparin, antitrombin III (AT III) ve antifibrinolitik ajanlarla pıhtılaştırıcı/fibrinolitik işlemleri bastırmaktır. Ayrıca, DIC’in özelliğine, etiyolojisine, hayvanın yaşına, hemoraji veya trombozisin yeri ve şiddetine, hemodinamik ve diğer klinik parametrelere bağlı olarak tedavi yönlendirilmelidir.

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Cite This Article

GÖKÇE, E., IRMAK, K. (2007). Disseminated intravascular coagulation (DIC). Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 13 - Sayı: 2, 215–222. https://ajindex.com/articles/273562

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