Postpartum Dönemde Gelişen Derin Ven Trombozu Vakası

This case is presented in order to emphasize that hereditary risk factors must be investigated, especially in young patients, although the patient already had an acquired risk factor such as pregnancy.

📌 3 Key Takeaways

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Objective & Hypothesis:The main reason for the increased risk of thromboembolism in pregnancy is hypercoagulability, which has likely evolved to protect women from the bleeding challenges of miscarriage and childbirth.

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Key Findings & Data:Women are at a 4- to 5-fold increased risk of thromboembolism during pregnancy and the postpartum period compared with when they are not pregnant.

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Conclusion & Impact:This case is presented in order to emphasize that hereditary risk factors must be investigated, especially in young patients, although the patient already had an acquired risk factor such as pregnancy.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

The main reason for the increased risk of thromboembolism in pregnancy is hypercoagulability, which has likely evolved to protect women from the bleeding challenges of miscarriage and childbirth. Women are at a 4- to 5-fold increased risk of thromboembolism during pregnancy and the postpartum period compared with when they are not pregnant. Risk factors include a history of thrombosis, inherited and acquired thrombophilia, maternal age greater than 35, certain medical conditions, and various complications of pregnancy and childbirth. In this report, a case of a 25-year-old woman diagnosed with deep vein thrombosis in the fourth week of the postpartum period is presented. After the investigating the reasons of deep vein thrombosis, heterozygote factor V Leiden mutation and heterozygote activated protein c resistance were detected. This case is presented in order to emphasize that hereditary risk factors must be investigated, especially in young patients, although the patient already had an acquired risk factor such as pregnancy.

Özet

Gebelikle gelişen tromboembolinin temel nedeninin hiperkoagülobilite olduğu bilinmektedir. Bu durumun düşük tehdidi ve doğumda annenin kanama riskini azaltmaya yönelik olarak geliştiği düşünülmektedir. Kadınlarda tromboemboli riski gebelik ve postpartum dönemde gebe olmayanlara göre 4-5 kat artmaktadır. Derin ven trombozu risk faktörleri arasında önceki tromboz öyküsü, edinsel ya da kalıtsal trombofili, anne yaşının 35'in üstünde olması, gebelik ve doğuma bağlı komplikasyonlar sayılabilir. Bu makalede 25 yaşında, postpartum 4. haftada derin ventrombozu tanısı alan bir olgu sunulmuştur. Etiyolojiye yönelik yapılan tetkiklerinde heterozigot Faktör V Leiden mutasyonu ve heterozigot aktive protein C rezistansı saptandı. Gebelik gibi tromboembolik olaya eğilim oluşturan edinsel bir risk faktörü olmasına rağmen özellikle genç hastalarda kalıtsal risk faktörlerinin mutlaka araştırılması gerektiğini vurgulamak amacıyla sunulmuştur.

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Cite This Article

ATALAY, H., TEKER, F., BÖYÜK, B., ÇELEBİ, A., AYAR, Y., EKİZOĞLU, İ. (2015). Postpartum Dönemde Gelişen Derin Ven Trombozu Vakası. JAREM, Cilt: 5 - Sayı: 1, 28–30. https://ajindex.com/articles/270401

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