Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2014 / Cilt: 24 - Sayı: 1

Fluoroquınolone resıstance ın escherıchıa colı straıns ısolated from rectal swabs before prostate bıopsy

Prostat biyopsisi öncesi alınan rektal sürüntü örneklerinden izole edilen escherichia coli izolatlarında florokinolon direnci

Pages
53–57
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Risk patients, rectal swab culture can be used in targeted prophylaxis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Transrectal ultrosound-accompanied biopsy is the gold procedure for the histological diagnosis of prostate cancer.
📊
Key Findings & Data:Materials Methods: This study involved 56 who were indicated with the prostate biopsy between April 2012 – October 2013 with prostate cancer suspicion were included in the study.
💡
Conclusion & Impact:Risk patients, rectal swab culture can be used in targeted prophylaxis.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Transrectal ultrosound-accompanied biopsy is the gold procedure for the histological diagnosis of prostate cancer. In this study, purpose to determine the prevalence of fluoroquinolone resistance Escherichia coli in intestinal flora of patients undergoing prostate biopsies with rectal swab culture. In addition, other antibiotics can be used in prostate biopsy prophylax- is was to determine the susceptibility. Materials Methods: This study involved 56 who were indicated with the prostate biopsy between April 2012 – October 2013 with prostate cancer suspicion were included in the study. The rectal samples culture were obtained from each patient before prostate biopsy. The patients who have a prostate biopsy history and prostate surgical operation history were excluded from the study. The records for the infections of those patients after the operation were kept. Findings: In this study, rectal swab culture were obtained from 56 patients. Rectal swab cultures taken from 56 patients ranged from 50 to 74 years of age was calculated as the average of 61. In 44 of the samples of E. coli produce. The lowest rates of resistance against to amikacin (2.3%) were detected. In 11 cases (25%) was detected in fluoroquinolone-resistant E. coli isolates. Developing a urinary tract infection after the procedure because of cases were hospitalized. The cases of rectal swab and uri- ne in culture, fluoroquinolone-resistant E. coli was detected. The blood cultures were negative. Conclusion: We have found high number of fluoroquinolone resistant E. coli strains in the rectal swab culture taken before the prostate biopsy. The fluoroquinolone resistance in the standart prophylaxis applications before the prostate biopsy should be kept in mind. Risk patients, rectal swab culture can be used in targeted prophylaxis.

Özet

Amaç: Prostat biyopsisi öncesi profilaksi için kullanılabilecek antibiyotiklerin duyarlılıklarının belirlenmesi amaçlanmıştır. Gereç ve Yöntem: Prostat kanseri şüphesi ile Nisan 2012–Ekim 2013 tarihleri arasında prostat biyopsi endikasyonu konan 56 hasta çalışmaya alındı. Her hastadan prostat biyopsisi işleminden önce rektal sürüntü örneği alındı. Geçirilmiş prostat bi- yopsi ve cerrahi öyküsü olan hastalar çalışma dışında bırakıldı. İşlem sonrası görülen tüm komplikasyonlar kaydedildi. Bulgular: Rektal sürüntü kültürü alınan 56 hastanın yaşları 50-74 arası değişmekte olup ortalama 61 olarak hesaplandı. Alı- nan örneklerin 44’ünde üreme pozitif bulundu. Yapılan tanımlama işlemleri sonrası üreme pozitif 44 vakanın Escherichia coli izolatları antibiyogram çalışmalarına dahil edildi. En düşük direnç oranı amikasin’e (%2,3) karşı saptanırken, olguların 11’inde (%25) florokinolon dirençli E. coli izolatı saptandı. Bir hasta işlem sonrası gelişen üriner infeksiyon nedeniyle hasta- neye yatırıldı. Söz konusu vakanın rektal sürüntü ve idrar kültüründe florokinolon dirençli E. coli saptandı. Olguların kan kültürlerinde üreme olmadı. Sonuç: Çalışmamızda PB öncesi alınan rektal sürüntü örnekleriyle yapılan kültürlerde yüksek oranda florokinolon dirençli E. coli saptanmıştır. Bu yüzden US eşliğinde yapılan transrektal prostat biyopsilerinin antibiyotik profilaksisinde florokinolon direnci akılda tutulmalıdır. Riskli olgularda profilaktik antibiyoterapi öncesinde rektal sürüntü kültürü kullanılabilir.

🔖

Cite This Article

BUDAK, S., ÇİFTÇİ, İ. H., KARAKEÇE, E., ADSAN, Ö., SAĞLAM, H. S., KÖSE, O., AYDEMİR, H., KUMSAR, Ş., ATİK, Y. T., GÜRKÖK, G. B. (2014). Fluoroquınolone resıstance ın escherıchıa colı straıns ısolated from rectal swabs before prostate bıopsy. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 24 - Sayı: 1, 53–57. https://ajindex.com/articles/268634

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Loeb S, Carter HB, Berndt SI, Ricker W, Schaeffer EM. Complications after prostate biopsy: data from SEER- Medicare. J Urol 2011;186: 1830–1834. Aron M, Rajeev TP and Gupta NP. Antibiotic prophylaxis for transrectal needle biopsy of the prostate: a randomized controlled study. BJU Int 2000; 85: 682-685.
  2. Tal R, Livne PM, Lask DM, Baniel J. Empirical management of urinary tract infections complicating transrectal ultrasound guided prostate biopsy. J Urol 2003; 169: 1762-1765.
  3. Otrock Z, Oghlakian G, Salamoun M, Haddad M, Bizri AR. Incidence of urinary tract infection following transrectal ultrasound guided prostate biopsy at a tertiary care medical center in Lebanon. Infect Control Hosp Epidemiol 2004;25: 873. Guidelines on Urological infections. European Association of Urology Guidelines. 2012.
  4. Nam RK, Saskin R, Lee Y, Lui Y, Law C, Klotz LH, et al. Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy. J Urol 2010; 183:963–968. Loeb S, van den Heuvel S, Zhu X, Bangma CH, Schroder FH, Roobol MJ. Infectious complications and hospital admissions after prostate biopsy in a European randomized trial. Eur. Urol. 2012; 61:1110 –1114. Sağlam HS, Öğütlü A, Demiray V, Karabay O. The role of escherichia coli’s in community acquired urinary infections and developing antibiotic resistance. Nobel Med 2012; 8(1): 67-71.
  5. Budak G, Budak S, Arı A, Özgenç O. Üroloji Hastalarında Çoklu Antibiyotik Dirençli Üriner İnfeksiyon Etkenleri ve Risk Faktörle- rinin Araştırılması. Journal of Clinical and Analytical Medicine DOI: 10.4328/JCAM.1892 Published Online: 15.08.2013.
  6. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003; 31:1250-6.
  7. Rosen R, Altwein J, Boyle P, Kirby RS, Lukacs B, Meuleman E, et al. Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). Eur Urol 2003;44: 637-649.
  8. Unsal A, Ayranci U, Tozun M. Prevalence of Lower Urinary Tract Symptoms Among Men In A Rural District of Western Turkey. Pak J Med Sci 2010;26(2):294-299.
  9. Oethinger M, Jellen-Ritter AS, Conrad S, Marre R, Kern WV. Colonization and infection with fluoroquinolone-resistant Escherichia coli among cancer patients: clonal analysis. Infection 1998; 26:379–84. Bettelheim KA. The genus Escherichia coli. In: Balows A eds. The prokaryotes: a handbook on the biology of bacteria: ecophysiology, isolates, identification,