Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2019 / Cilt: 29 - Sayı: 2

Visual Evoked Potential Findings in Patients With Multiple Sclerosis That Have Not Experienced an Optic Attack

Optik Atak Geçirmemiş Olan Multipl Skleroz Hastalarında Görsel Uyarılmış Potansiyel Bulguları

Pages
167–169
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We also observed that VEP is a sensitive, and easişy applicable diagnostic tool in the assesment of asymptomatic optic neuritis attacks in patients with MS.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Multiple sclerosis (MS) is a chronic, inflammatory, degenerative disease of the central nervous system.
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Key Findings & Data:VEP results are observed in 50 patients.
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Conclusion & Impact:We also observed that VEP is a sensitive, and easişy applicable diagnostic tool in the assesment of asymptomatic optic neuritis attacks in patients with MS.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Multiple sclerosis (MS) is a chronic, inflammatory, degenerative disease of the central nervous system. Visual evoked potential (VEP) tests are performed to assess conduction along the visual pathways. Involvement of visual pathways without visual complaints may be shown in VEP studies. In this study, VEP findings are investigated in MS patients without history of optic neuritis episodes. Methods: The study was performed in Izmir Tepecik Educational and Research Hospital, Department of Neurology. VEP results are observed in 50 patients. Results: In 26 of 50 patients, P100 latencies were above the normal limits in bilateral VEP tests. Conclusion: In our study, we showed that asymptomatic attacks of optic neuritis are frequently seen in MS patients. Our results are concordant with previous findings. We also observed that VEP is a sensitive, and easişy applicable diagnostic tool in the assesment of asymptomatic optic neuritis attacks in patients with MS.

Özet

Amaç: Multipl skleroz (MS), genellikle genç erişkinleri etkileyen santral sinir sisteminin demiyelinizasyon ve aksonal dejenerasyonla giden inflamatuvar kronik bir hastalığıdır. Görsel uyarılmış potansiyel (VEP) çalışmaları, MS hastalarında optik sinir hasarını gösteren, duyarlı ve maliyeti düşük bir tanısal test yöntemidir. VEP ile klinik olarak optik nörit atağı öyküsü olmayan MS hastalarında da ön görsel yol tutulumuna ait bulgular görülebilir. Bu çalışmada, optik nörit atağı geçirmemiş MS hastalarında VEP bulguları araştırılmıştır. Yöntem: Çalışmaya İzmir Tepecik Eğitim ve Araştırma Hastanesi Nöroloji Kliniğinde takip edilen, daha önce optik nörit atağı geçirmemiş 50 MS hastası alınmıştır. Hastaların VEP bulguları incelenmiştir. Bulgular: Hastaların 26’sında her iki tarafta VEP tetkikinde uzamış P100 latansı olduğu görülmüştür. Sonuç: Çalışmamız, geçmiş çalışmalarla uyumlu olarak, MS hastalarında sık olarak asemptomatik optik nörit atakları görüldüğünü doğrulamıştır. MS hastalarında asemptomatik optik nörit ataklarının saptanmasında VEP’in duyarlı ve uygulanması kolay bir yöntem olduğu düşünülmüştür.

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Cite This Article

SARITEKE, A., ULUDAĞ, İ. F., ŞENER, U., TOKUÇOĞLU, F. (2019). Visual Evoked Potential Findings in Patients With Multiple Sclerosis That Have Not Experienced an Optic Attack. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 29 - Sayı: 2, 167–169. https://ajindex.com/articles/268554

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References (9)

  1. Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol. 2004;55:458-68. Paty DW. Ebers GC: Clinical features. Paty DW, Ebers GC (Ed). (1998) Multiple Sclerosis. F. A. Davis Company, Philadelphia. 135-91.
  2. Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2018;17(2):162-73.
  3. Halliday AM, McDonald WI, Mushin J. Delayed VER in optic neuritis. Lancet. 1972;1:982-5. Brazier MAB. Pioneers in the discovery of evoked potentials. Electroenceph. Clin Neurophysiol. 1984;59:2-8.
  4. Comi G, Leocani L, Medaglini S, Locatelli T, Martinelli V, Santuccio G, Rossi P. Mesasuring evoked responses in multiple sclerosis. Mult Scler. 1999;5:263-67.
  5. Zgorzalewicz M, Michalowska-Wender G, Losy J, Wender M. The value of VEP assessment and imunological CSF analysis in the diagnosis of childhood and Juvenile MS. Przegl Lek. 2003;60(Suppl 1):1-4. Sanchez-Calderon M, de Santest Martin S, Angulat, Careaga J, Campos-Castello J. Multiple sclerosis in childhood our experience and a review of literature. Rev Neurol. 1998;27:(156):237-41.
  6. Asselman P, Chadwick DW, Marsden DC, Visual evoked responses in the diagnosis and manegement of patients suspected of multiple sclerosis. Brain. 1975;98:261-82.
  7. Celesia GG, Evoked potetials techniques in the evaluation of visual function. J Clin Neurophysiol. 1984;1:55-76.
  8. Sisto D, Trojano M, Vetrugno M, Trabucco T, Iliceto G, Sborgia C, Subclinical visual involvement in multiple sclerosis: a study by MRI, VEPs, frequency-doubling perimetry, standard perimetry, and contrast sensitivity. Invest Opthalmol Vis Sci. 2005;46:1264-68.
  9. Voitenkov V, Skripchenko N, Klimkin A. Visual pathways involvement in clinically isolated syndrome in children. Int J Opthalmol. 2015;8:382-84.