Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2007 / Cilt: 17 - Sayı: 2

Retrospective evaluation of the patients with lip masses admitted to our clinic

Dudakta kitle ile başvuran olgularımızın retrospektif değerlendirilmesi

Pages
93–98
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Early diagnosis and proper surgical appoach is important in these patients both for survival without disease and cosmetic and functional reasons.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Lip masses are classified as benign, premalign and malign tumors.
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Key Findings & Data:Methods: 204 patients who applied to our clinic with the complaint of suspicious lesion on the lip between the dates January 2001-January 2006 were included in this study and were followed up median 38 months.
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Conclusion & Impact:Early diagnosis and proper surgical appoach is important in these patients both for survival without disease and cosmetic and functional reasons.
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Lip masses are classified as benign, premalign and malign tumors. Patients with lip masses usually apply to the hospitals with nodular lesions, superficial ulcerations with or without enduration or bleeding and nonhealing wounds. Early diagnosis and surgical approach is important in patients with lip masses. Our aim in this study is to evaluate the patients who applied to our clinic with lip masses within the last five vears in terms of demografic characteristics, histopathological diagnosis and surgical approach. Methods: 204 patients who applied to our clinic with the complaint of suspicious lesion on the lip between the dates January 2001-January 2006 were included in this study and were followed up median 38 months. Excisional biopsy was performed to 162 of them for diagnostic and/or treatment purposes wheras radical surgery was performed in 34 patients according to the histopathological results. Eight of them were accepted as inoperable and referred to radiochemotherapy . Results: The male/female ratio was 135/69 (% 66.1 - % 33.8) and the median age at the time of diagnosis was median 59 years (range 34 to 74 years). Their histopathological evaluation revealed that 54.4% was in benign and 45.5% was in malign character. Capiller hemangioma (15.3%), ulcerate inflamation (14.4%), pyogenic granuloma (9.9%) and fibromas (9%) were the most frequent lip masses in our study. While 88 of the 93 cases with malign hispothapathology were diagnose as epidermoid cancer, 2 patients were reported as verrucous carcinoma, 1 patient malign pleomorphic adenoma, 1 patient chondroid sarcoma and 1 patient rhabdomyosarcoma. The surgical intervention was chosen according to the location and size of the cancer as well as preservation of the cosmetic and function of the lip. Cancer was detected on the upper lip in 4 and on the lower lip in 30 patients. Moreover, with the purpose of control of the disease, the necessary neck dissection interventions were applied in 21 of our patients. Conclusion: 45.5% of our patients with masses on the lip were malign and epidermoid carcinoma was found to be most frequent lip cancer (94.6%). Early diagnosis and proper surgical appoach is important in these patients both for survival without disease and cosmetic and functional reasons.

Özet

Amaç: Dudak kitleleri benign, premalign ve malign olarak sınıflandırılır. Olgular dudakta noduler lezyon, yüzeyel/endure ülserasyon, iyileşmeyen ve/veya kanayan yara yakınmaları ile başvururlar. Bu lezyonlarda erken histopatolojik tanı ve tedavi önemlidir. Amacımız, son 5 yılda hastanemiz Kulak Burun Boğaz ve Baş-Boyun Cerrahisi Kliniğine dudakta kitle nedeni ile başvuran olguları demografik özellikleri, histopatolojik tanı ve cerrahi yaklaşım yönünden irdelemektir. Yöntem: Çalışmaya, Ocak 2001-Ocak 2006 tarihleri arasında dudakta şüpheli lezyon yakınması ile kliniğimize başvuran, median 38 ay izlenen 135'i erkek toplam 204 olgu dahil edilmiştir. Bu hastalardan 162'sinde tanı ve/veya tedavi amaçlı eksizyonel biyopsi yeterli olurken, 34 hastaya histopatoloji sonucuna göre radikal cerrahi uygulanmış, 8 hasta ise inoperatif kabul edilerek radyokemoterapiye sevk edilmiştir. Bulgular: Yaşları 34-74 yıl olan (median 59 yıl) 204 hastanın 135'i(%66.18) erkek, 69'u (%33.82) kadındır. Hastaların histopatolojik tanıları incelendiğinde %54.4'ünün benign, %45.5'inin malign olarak rapor edildiği görülmüştür. Benign olarak değerlendirilen lezyonların çoğunu kapiller hemanjiom (%15.3), ülsere yangı (%14.4), piyojenik granulom (%9.9) ve fibrom (%9) oluşturmuştur. Malign histopatolojiye sahip 93 olgudan 88'i (%%94.6) epidermoid kanser tanısı alırken, 2 hasta verrüköz karsinom, 1 hasta malign plemorfik adenom, 1 hasta kondroid sarkom, 1 hasta rabdomiyosarkom olarak rapor edilmiştir. Hastalarımıza kanserin yerleşim yerine, büyüklüğüne ve boyun yayılımına göre gerekli cerrahi girişim uygulanırken, hastahksız yaşam kadar, dudağın fonksiyonel ve kozmetik açıdan korunması planlanarak gerekli cerrahi teknik seçilmiştir. Radikal cerrahi uygulanan 34 hastanın 4'ünde tümör üst dudağa lokalize iken, 30'unda alt dudak yerleşimlidir. Ayrıca hastalığın kontrolü amacı ile 21 hastamıza gerekli görülen boyun diseksiyonu girişimleri uygulanmıştır. Sonuç: Olgularımızdaki dudak kitlelerinin %45.5'ini malign histopatoloji oluşturmuş, bu grup içinde epidermoid karsinom %94.6 ile birinci sırada yer almıştır. Dudak kitlelerinin erken tanı ve uygun cerrahi tedavisi hem hastahksız yaşam sağlama hem de kozmetik ve fonksiyonel nedenlerle önemlidir.

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Cite This Article

ÇUKUROVA, İ., ÖZKUL, M. D., KARAKURT, S. E., MENGİ, E., TORUN, M. T., BAYOL, Ü. (2007). Retrospective evaluation of the patients with lip masses admitted to our clinic. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 17 - Sayı: 2, 93–98. https://ajindex.com/articles/268516

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References (15)

  1. Kaya S. Dudak neoplazmlan. in: Çelik O editor. Kulak burun boğaz hastalıkları ve baş boyun cerra hisi. İstanbul: Turgut Yayıncılık; 2002. p. 585-601
  2. Backer SR. Malignant neoplasms of the oral cavity. In: Cummings CW, Fredrickson JM, Harker LA, Krause CJ, Schuller DE, editors. Otolaryngology- head and neck surgery. 2nd ed, St. Louis: Mosby Year Book; 1992. p. 1248-305
  3. Zitsch RP. Carcinoma of the lip. Otothryngol Clin North Am 1993;26:265-77
  4. Duffey DC, Eversole E, Abemayor E. Oral lichen planus and its association with squamosus cell carcinoma. Laryngoscope 1996;106:357-62
  5. Başerer N. Oral kavite kanserleri. In: Engin K, Erişen L. Baş boyun kanserleri. Bursa: Nobel Yayıncılık; 2003. p. 235-71
  6. Karadeniz AN. Baş boyun ve tiroid kanserleri, in: Topuz E, Aydıner A, Karadeniz AN editörler. Klinik onkoloji. İstanbul: Tunç matbaası, 2000;161-200
  7. Calcaterra TC, Juillard GJF, Blackwell KE. Oral Cavity and Oropharynx İn: Cummings CW, Fredrickson JM, Harker LA, Krause CJ, Schuller DE, editors. Oto laryngology-head and neck surgery. 2nd ed, St. Louis: Mosby Year Book; 1993. p. 1248-1305
  8. Frierson HF, Cooper PH. Prognostic factors in squamos cell carsinoma of the lower lip. Humon Pathol 1986;17:346-54
  9. Koc C, Akyol MU, Celikkanat S, Cekic A, Ozdem C. Role of suprahyoid neck dissection in treatment of squamos cell carcinoma of the lower lip. Ann Otol Rhinol Laryngol 1997;106(9):787-9
  10. Kıvanç A. Dudak tümörleri. In: Koc C, editor. Kulak burun boğaz hastalıkları ve bas-boyun cerrahisi. Ankara: Gunes Kitabevi Ltd. Şti. 2004;941-953
  11. Hoşal AŞ. Oral kavite ve orofarenks neoplazmlan. in: Çelik O editor. Kulak burun boğaz hastalıkları ve baş boyun cerrahisi. İstanbul: Turgut Yayıncılık; 2002. p.601-619
  12. Veissler MC. Management of the primary site oral cavity. İn: Pillsbury HC, Goldsmith NM, editors. Operative challenges. Ch. 17, Chiago: Year Book Medical Publication, 1990; 300-7
  13. Holt GR, Surgical therapy of oral cavity tumors. Lip tumors. İn: Thawley SE, Panje WR, editors. Compre hensive management of head and neck tumors. Vol. 1, Ch. 25, Philadelphia: Saunders, 1987;557-63
  14. Esclamado RM, Krause CJ. Lip Cancer. İn: Bailey BJ, editor. Head and neck surgery otolaryngology. Vol. 2 2nd ed, Ch. 106, Philadelphia: Lippincott Raven, 1993;1509-1521
  15. Gullane P. Dudak, oral kavite. İn: Gluckman J, Gallone P, Johnson J, editors. (Çeviri editörleri Cevanşir B, Kıyak E.) Baş boyun tümörlerine yaklaşım. İstanbul: Nobel Tıp kitabevi, 199