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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2012 / Cilt: 22 - Sayı: 3

Factors assocıated wıth short and long-term graft survıval and theır predıctors ın kıdney transplantatıon

Son dönem böbrek yetmezlikli hastalarda kısa ve uzun dönem greft sağkalımını belirleyen faktörler ve bunlara ait belirleyiciler

MEHMET TANRISEV
Hülya ÇOLAK
Ali Rıza ÜNSAL
Seda EVİRGEN
Mustafa CİRİT
Hüseyin TÖZ
Pages
139–145
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Although there are some problems for transplantations from marginal donors; they still have superior outcomes in terms of survival, life quality and country’s economial welfare in comparision with being in waiting list for live-donor and going into dialysis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim : The aim of this study was to identify the associated factors with short and long term graft survival and their predictors in renal transplantation which is the optimum treatment method for end-stage renal failure.
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Key Findings & Data:Material and Method: Data of 400 patients who underwent renal transplantation at Ege University Organ Transplantation Unit were retrospectively investigated.
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Conclusion & Impact:Conclusion: Although there are some problems for transplantations from marginal donors; they still have superior outcomes in terms of survival, life quality and country’s economial welfare in comparision with being in waiting list for live-donor and going into dialysis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim : The aim of this study was to identify the associated factors with short and long term graft survival and their predictors in renal transplantation which is the optimum treatment method for end-stage renal failure. Material and Method: Data of 400 patients who underwent renal transplantation at Ege University Organ Transplantation Unit were retrospectively investigated. Findings: The age, gender, primary kidney disease, weight before transplantation, blood transfusion, HCV serology, the type and duration of dialysis and number of transplantations for patients were primarily determined. Furthermore, the gender and age of donor, live-cadaver, ideal-marginal, haplotype or miss-match and duration of cold ischemia were also determined. Survival rates after exclusion of general graft survival and death were significant in ideal and elderly live-donor (p<0.02, p<0.01) and ideal and marginal cadaver (p<0.007, p<0.03) however, there was not significant relationship between elderly live and marginal cadaver (p<0.25, p>0.63). Conclusion: Although there are some problems for transplantations from marginal donors; they still have superior outcomes in terms of survival, life quality and country&#8217;s economial welfare in comparision with being in waiting list for live-donor and going into dialysis.

Özet

Amaç: Bu çalışmada amacımız son dönem böbrek yetmezliğinin en seçkin tedavisi olan böbrek naklinde greftin kısa ve uzun dönem sağkalımına etki eden faktörleri ve bunlara ait belirleyicileri tespit etmektir. Gereç ve Yöntem: Ocak ayı ile 2005 haziran ayı arasında Ege Üniversitesi Organ Nakli Merkezinde böbrek nakli olan toplam 400 hastanın verileri retrospektif olarak değerlendirilmiştir. Bulgular: Genel greft sağkalımı oranları 3. ve 5. yıllarda ideal ve yaşlı canlı donörde sırasıyla % 90-% 76 ya % 84-% 62 dir( p<0.02, p<0.01). İdeal ve marjinal kadavrada ise %90-%76 ya %67-%67 dir( p<0.007, p<0.03). Bu da bize greftin sağkalımında en önemli faktörün marjinalitesi olduğunu göstermektedir. Sonuç: Marjinal donörlü nakiller optimale göre daha sıkıntılı olsa da sağkalım, hayat kalitesi ve ülke ekonomisi açısından sonuçlar bekleme listesinde kalıp diyalize girme ile kıyaslandığında daha üstün görülmektedir.

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Cite This Article

TANRISEV, M., ÇOLAK, H., ÜNSAL, A. R., EVİRGEN, S., CİRİT, M., TÖZ, H. (2012). Factors assocıated wıth short and long-term graft survıval and theır predıctors ın kıdney transplantatıon. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 22 - Sayı: 3, 139–145. https://ajindex.com/articles/268406

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