Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2016 / Cilt: 26 - Sayı: 1

Malign tümörlerde yaygın osseöz metaplazi: Mesanenin yüksek dereceli ürotelyal karsinomu ve metastatik kolon adenokarsinomu

Widespread osseous metaplasia in malign tumors: High grade papillary urothelial carcinoma of the bladder and metastatic colonic adenocarcinoma

Pages
73–76
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However osteoid metaplasia is an important incidental finding in that it can lead to misinterpretations as bone invasion when it accompanies malignant tumors

📌 3 Key Takeaways

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Objective & Hypothesis:Osteoid metaplasia is a rarely seen characteristic feature among all tumor types.
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Key Findings & Data:Dystrophic calcifications can be occasionally seen in necrotic areas of tumors.
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Conclusion & Impact:However osteoid metaplasia is an important incidental finding in that it can lead to misinterpretations as bone invasion when it accompanies malignant tumors
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Osteoid metaplasia is a rarely seen characteristic feature among all tumor types. Dystrophic calcifications can be occasionally seen in necrotic areas of tumors. However actual bone formation also termed as osteoid metaplasia or heterotopic bone formation is a rarely developed incidental microscopic finding.In this case report we presented a case diagnosed as a high grade papillary urothelial carcinoma of the bladder associated with osteoid metaplasia, and another one with diagnosis of metastatic adenocarcinoma of colon.In both cases, presence of diffuse osteoid metaplasia accompanying malignant tumors is a remarkable finding. Two cases with incidentally detected osteoid metaplasia associated with different histopathological diagnosis were presented. Osteoid metaplasia is a rare entity which accompanies both benign and malignant tumors and its etiopathogenesis is still unknown. However osteoid metaplasia is an important incidental finding in that it can lead to misinterpretations as bone invasion when it accompanies malignant tumors

Özet

Osteoid metaplazi tüm tümör tiplerinde görülebilen ender bir özelliktir. Tümörlerin nekrotik alanlarında zaman zaman distrofik kalsifikasyon görülebilir. Ancak osteoid metaplazi ya da heterotopik kemik formasyonu olarak adlandırılan gerçek kemik oluşumu ender olarak gelişir ve insididental olarak saptanan mikroskopik bir bulgudur. Bu sunumda osteoid metaplazinin eşlik ettiği "mesanenin yüksek dereceli papiller ürotelyal karsinomu" ve "metastatik kolon adenokarsinomu" olarak tanı alan iki olgu sunulmuştur. Her iki olguda da malign tümörlere eşlik eden yaygın osteoid metaplazi varlığı dikkat çekmektedir. Farklı patolojik tanılara eşlik eden ve insidental olarak saptanan osteoid metaplazi görülen iki olgu sunuldu. Osteoid metaplazi hem benign hem de malign tümörlere eşlik eden ender bir antitedir ve etiopatogenezi halen bilinmemektedir. Ancak osteoid metaplazi, malign tümörlere eşlik etmesi durumunda kemik invazyonu açısından yanlış yorumlara neden olabileceği için önemli bir bulgudur

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Cite This Article

BASMACI, G., ELİYATKIN, N. Ö., ERSAVAŞ, S., POSTACI, H. (2016). Malign tümörlerde yaygın osseöz metaplazi: Mesanenin yüksek dereceli ürotelyal karsinomu ve metastatik kolon adenokarsinomu. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 26 - Sayı: 1, 73–76. https://ajindex.com/articles/268374

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