Journals / Haseki Tıp Bülteni / 2011 / Cilt: 49 - Sayı: 1

Comparison between predialysis and hemodialysis patients regarding the cardiac structure and functions and the related factors

Prediyaliz ve hemodiyaliz hastalarında kalp yapı ve fonksiyonlarının ve buna ilişkin faktörlerin karşılaştırılması

Pages
20–25
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Besides investigating all the factors involved in the pathogenesis of disease, echocardiographic evaluation should be done periodically in both predialysis and dialysis patients. (The Medical Bulletin of Haseki 2011; 49: 20-5)

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In our study we compared the structure and functions of the heart between predialysis and hemodialysis patients and investigated the related factors.
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Key Findings & Data:Methods: This study included a total of 105 patients (mean age: 18-75 years): 51 on continuous hemodialysis and 54 predialysis subjects followed by the Nephrology Clinic and not yet involved in dialysis program.
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Conclusion & Impact:Besides investigating all the factors involved in the pathogenesis of disease, echocardiographic evaluation should be done periodically in both predialysis and dialysis patients. (The Medical Bulletin of Haseki 2011; 49: 20-5)
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: In our study we compared the structure and functions of the heart between predialysis and hemodialysis patients and investigated the related factors. Methods: This study included a total of 105 patients (mean age: 18-75 years): 51 on continuous hemodialysis and 54 predialysis subjects followed by the Nephrology Clinic and not yet involved in dialysis program. Laboratory data showing calcium-phosphorus metabolism disorders and transthoracic echocardiography results were evaluated. Results: Serum parathormone, phosphorus, calcium x phosphorus, alkaline phosphatase levels were significantly higher in the dialysis group compared to the predialysis group (pO.OOl). No statistical difference was found between the groups with regard to median values of ejection fraction, mean values of left ventricular hypertrophy index and frequencies of diastolic dysfunction, and valve calcifications. Conclusion: Since predialysis group had higher smoking rate (A .6%), low-density lipoprotein cholesterol levels [122 (100-148) mg/dL] and body mass index (27.6±3.8 kg/m2) and had been receiving systemic drugs in different ratios, the two groups were not similar regarding the traditional risk factors; thus, this may be the explanation for finding no statistical difference in echocardiographic parameters. Besides investigating all the factors involved in the pathogenesis of disease, echocardiographic evaluation should be done periodically in both predialysis and dialysis patients. (The Medical Bulletin of Haseki 2011; 49: 20-5)

Özet

Amaç: Çalışmamızda kronik hemodiyaliz tedavisi gören hastalar ile prediyalitik dönemdeki hastaların kalp yapı ve fonksiyonlarını karşılaştırdık ve buna ilişkin faktörleri inceledik. Yöntemler: Sürekli hemodiyalize giren 51 ve Nefroloji polikliniğinde takip edilen diyaliz programında olmayan prediyaliz döneminde 54 olgu olmak üzere toplam 105 hasta (18-75 yaş) çalışmaya alındı. Kalsiyum-fosfor metabolizması bozukluğu laboratuvar verileri ve transtorasik ekokardiyografi bulguları değerlendirildi. Bulgular: Prediyaliz hastalarına kıyasla serum parathormon, fosfor, kalsiyum x fosfor, alkalen fosfataz düzeyleri diyaliz hastalarında istatistiksel olarak anlamlı derecede yüksek bulundu (p<0.001). İki grubun ejeksiyon fraksiyonu medyan değerleri ve sol ventrikül kitle indeksi ortalamaları ile; kapak kalsifikasyonları ve diyastolik disfonksiyon frekansları istatistiksel olarak farklı değildi. Sonuç: Prediyaliz grubunda geleneksel risk faktörleri açısından sigara kullanım oranının (%29.6), düşük-yoğunluklu lipoprotein kolesterol düzeyinin [122 (100-148) mg/dL] ve vücut kitle indeksinin (27.6±3.8 kg/m2) daha yüksek oluşu ve kullandıkları sistemik ilaç oranının farklı oluşu nedeniyle gruplar benzer değildi; iki grup arasında ekokardiyografik bulgularda beklenen istatistiksel farkın bulunamayışı bununla açıklanabilir. Patogenezde yer alan tüm faktörlerin araştırılmasının yanı sıra, hem prediyaliz ve hem diyaliz hastalarının düzenli aralıklarla ekokardiyografik incelemeye alınması önerilir. (Haseki Tıp Bülteni 2011; 49: 20-5)

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Cite This Article

ÖZDEMİR, R. B., MÜDERRİSOĞLU, C., BESLER, M., SARIKAMIŞ, Ç., ÖZDEMİR, A. T., ARAL, H., GÜRCAN, Z., USTA, M. (2011). Comparison between predialysis and hemodialysis patients regarding the cardiac structure and functions and the related factors. Haseki Tıp Bülteni, Cilt: 49 - Sayı: 1, 20–25. https://ajindex.com/articles/267986

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