Journals / Haseki Tıp Bülteni / 2017 / Cilt: 55 - Sayı: 1

Radikal Prostatektomi Materyallerinde Parsiyel Örnekleme Yöntemi Ne Kadar Güvenilir?

How Much Extent can We Rely on Partial Sampling of Radical Prostatectomy Specimens?

Pages
27–31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Partial sampling method can be a choice of grossing of radical prostatectomy specimens with the help of macroscopic, clinical and radiological findings.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Prostatic adenocarcinoma is the most common cancer among men in the world and prostatectomy specimens are one of the most commonly encountered materials in pathology laboratories.
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Key Findings & Data:Methods:­ In this study, we evaluated 50 radical prostatectomy specimens using total and partial sampling methods and compared the results.
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Conclusion & Impact:Conclusion: Partial sampling method can be a choice of grossing of radical prostatectomy specimens with the help of macroscopic, clinical and radiological findings.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Prostatic adenocarcinoma is the most common cancer among men in the world and prostatectomy specimens are one of the most commonly encountered materials in pathology laboratories. Histopathological evaluation of radical prostatectomy specimens provides very important prognostic parameters to predict patient's prognosis and to choose an appropriate treatment. There is no globally accepted standard grossing method for radical prostatectomy materials. Different grossing protocols are preferred in different centers considering financial condition, storage spaces, number of technicians and pathological workload. Methods:­ In this study, we evaluated 50 radical prostatectomy specimens using total and partial sampling methods and compared the results. Results:­As a result of the partial sampling method the number of blocks per case was reduced prominently, and depending on this workload and financial burden also reduced. The correlation between total and partial sampling methods was statistically significant. Conclusion: Partial sampling method can be a choice of grossing of radical prostatectomy specimens with the help of macroscopic, clinical and radiological findings.

Özet

Amaç: Prostatik adenokarsinomlar dünyada erkeklerde görülen kanserler arasında en yaygın olarak görülen kanser olup radikal prostatektomi materyalleri patoloji laboratuvarlarında en çok takibe alınan materyallerin başında gelmektedir. Prostatektomi materyallerinin histopatolojik incelemesi sonucunda elde edilen prognostik parametreler hastalığın seyri ve uygulanacak tedavi yöntemi konusunda klinisyene yol göstermektedir. Radikal prostatektomi materyalleri için dünya çapında kabul görmüş tek bir örnekleme yöntemi bulunmamaktadır. Farklı merkezlerde farklı yöntemler tercih edilmektedir. Bu tercihte mali sorunlar, arşivleme kapasitesi, personel sayısı gibi faktörler rol oynamaktadır. Metod: Bu çalışmada kliniğimize kabul edilen 50 radikal prostatektomi materyali total ve parsiyel örnekleme yöntemi ile değerlendirilerek sonuçlar karşılaştırılmıştır. Bulgular: Parsiyel örnekleme yöntemi sonucunda elde edilen blok sayısında belirgin ve dolayısıyla iş yükünde ve mali yükte bir azalma görülürken sonuçların istatistiksel olarak korelasyon gösterdiği sonucuna varıldı.Sonuç: Çalışmamız göstermiştir ki, parsiyel örnekleme yöntemi ile klinik için önemli olan parametrelere ulaşılabilmektedir ve klinik ve radyolojik bulgulardan da destek alınarak radikal örnekleme yerine tercih edilebilecek bir yöntemdir.

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Cite This Article

ÜNAL, T. D. K., ERDOĞAN, A. S. O., GÜRÇAY, N., ALPER, M. (2017). Radikal Prostatektomi Materyallerinde Parsiyel Örnekleme Yöntemi Ne Kadar Güvenilir?. Haseki Tıp Bülteni, Cilt: 55 - Sayı: 1, 27–31. https://ajindex.com/articles/267820

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References (16)

  1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin 2015;65:5-29
  2. Kench JG, Clouston DR, Delprado W, et al. Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens. Pathology 2011;43:410-9
  3. Samaratunga H, Montironi R, True L, et al. International society of urological pathology (ISUP) consensus conference on handling and staging of radical prostatectomy specimens. working group 1: specimen handling. Mod Pathol 2011;24:6- 15
  4. True LD. Surgical pathology examination of the prostate gland. Practice survey by American society of clinical pathologists. Am J Clin Pathol 1994;102:572-9
  5. Doganavsargil B, Nalbantoglu I, Hekimgil M. Handling and reporting of radical prostatectomy specimens: A practice survey among pathologists. Turkish Journal of Pathology 2007;23:74-81
  6. Egevad L. Handling of radical prostatectomy specimens. Histopathology 2012;60:118-24
  7. Gill PS, Roberts IS, Browning L, et al. The handling and sampling of radical prostatectomy specimens for reporting and research: the Oxford approach. J Clin Pathol 2012;65:1057- 61
  8. Ohori M, Kattan M, Scardino PT, Wheeler TM. Radical prostatectomy for carcinoma of the prostate. Mod Pathol 2004;17:349-59
  9. Sung MT, Davidson DD, Montironi R, Beltran AL, Cheng L. Radical prostatectomy specimen processing: A critical appraisal of sampling methods. Diagn Histopatol 2007;13:490-8
  10. Sringley JR. Key issues in handling and reporting radical prostatectomy specimens. Arch Pathol Lab Med 2006;130:303-17
  11. Montironi R, Van der Kwast T, Boccon-Gibod L, Bono AV, Boccon-Gibod L. Handling and pathology reporting of radical prostatectomy specimens. Eur Urol 2003;44:626-36
  12. Renshaw AA. Correlation of gross morphologic features with histologic features in radical prostatectomy specimens. Am J Clin Pathol 1998;110:38-42
  13. Bell KB, Kida M, Cooper K. Histopathology sampling of radical prostatectomy specimens: representative or entire submission? Histopathology 2011;59:1013-4
  14. Sehdev AE, Pan CC, Epstein JI. Comparative analysis of sampling methods for grossing radical prostatectomy specimens performed for nonpalpable (stage T1c) prostatic adenocarcinoma. Hum Pathol 2001;32:494-9
  15. Kim K, Pak PJ, Ro JY, Shin D, Huh SJ, Cho YM. Limited sampling of radical prostatectomy specimens with excellent preservation of prognostic parameters of prostate cancer. Arch Pathol Lab Med 2009;133:1278-84
  16. Llanos CA, Bl