Tunnel vision in visual field analysis after low dose tamoxifen treatment

Objective & Hypothesis:A 45-year-old female patient with a 5-year history of right breast carcinoma and mastectomy and who was taking tamoxifen presented to our clinic with peripheral visual loss and decreased visual acuity.

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Key Findings & Data:In her ophthalmologic examination no pathology was detected in either anterior or posterior segments.

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Conclusion & Impact:Visual field analysis showed significant tunnel vision in both eyes.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

A 45-year-old female patient with a 5-year history of right breast carcinoma and mastectomy and who was taking tamoxifen presented to our clinic with peripheral visual loss and decreased visual acuity. In her ophthalmologic examination no pathology was detected in either anterior or posterior segments. Fundus fluorescein angiography showed reticular pigment epithelial changes in the peripheral retina. Retinal nerve fiber layer thickness assessed with optical coherence tomography was normal. Visual field analysis showed significant tunnel vision in both eyes.

Özet

Kliniğimize başvuran ve 5 yıl önce meme karsinomu nedeni ile sağ mastektomi sonrası tamoksifen kullanan 45 yaşındaki olgunun düşük görme keskinliği ve özellikle görme alanında daralma hikayesi mevcuttu. Hastanın oftalmolojik muayenesinde ön ve arka segmentte herhangi bir patoloji yoktu. Fundus Fluoresein Anjiyografisinde (FFA) perifer retinada yaygın retiküler pigment epitel görünümü dışında patoloji saptanmadı. Makula FFA, Optik Koherens Tomografi (OCT) ve Retina Sinir Lifi Tabakası (RNFL) muayenesi doğaldı. Görme alanında ise belirgin tünel görünümü saptandı.

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Cite This Article

ŞENDÜL, S. Y., ÜÇGÜL, C., KURNAZ, Y., TÜRKER, Ç., GÜVEN, D. (2010). Tunnel vision in visual field analysis after low dose tamoxifen treatment. Glokom Katarakt, Cilt: 5 - Sayı: 2, 124–126. https://ajindex.com/articles/267695

References (1)

Fraunfelder F.T.:Drug-Induced Ocular Side Effects. 1996. 2. Salomão SR,Watanabe SE,Berezovsky A,et al.: Multifocal electroretinography, color discrimination and ocular toxicity in tamoxifen use. 2007;32:345-352. 3. Gorin MB,Day R,Costantino JP,et al.:Long-term tamoxifen citrate use and potential ocular toxicity.Long-term tamoxifen citrate use and potential ocular toxicity. Am J Ophthalmol. 1998;125:493-501. 4. Noureddin BN, Seoud M,Bashshur Z, et al.:Ocular toxicity in low-dose tamoxifen: a prospective study.Eye.1999;13:729-733. 5. Eisner A,O’Malley JP, Incognito LJ,Toomey MD, Samples JR: Small opti cup sizes among women using tamoxifen:assessment with scanning laser ophthalmoscopy.Curr Eye Res. 2006;31:367-379. 6. Yanyali AC,Freund KB, Sorenson JA, et al.: Tamoxifen retinopathy in a male patient.Am J Ophthalmol.2001;131:386-387. 7. Parkkari M,Paakkala AM,Salminen L, et a.:Finnish Breast Cancer Group.Ocular side-effects in breast cancer patients treated with tamoxifen and toremifene: a randomized follow-up study. Acta Ophthalmol Scand. 2003;81:495-499. 8. Eisner A, Austin DF Samples JR: Shortwavelength automate perimetry and tamoxifen use. BrJOphthalmol.2004;88:125-130. 9. Aslan Ö.,Ttırhış H., Batman C.,ve ark.:Düşük doz kullanımda tamoksifen retinopatisi.Ret-Vit.2007;15:283-286.