Journals / Hacettepe Journal of Biology and Chemistry / 2011 / Cilt: 39 - Sayı: 4

Antimicrobial activity of Emblica officinalis, Saraca indica and Terminalia arjuna against Multi-Drug Resistant MDR Bacterial Pathogens

Çoklu-İlaç Dirençli Bakteriyal Patojenlere Karşı Emblica officinalis, Saraca indica ve Terminalia arjuna'nın Antimikrobiyal Aktivitesi

Pages
435–437
Publication Date
2011-12-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further study on purification of active ingredient and their efficacy in controlling MDR is in progress.

📌 3 Key Takeaways

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Objective & Hypothesis:Plant based antimicrobials represent a vast untapped source of medicines and has enormous therapeutic potential.
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Key Findings & Data:In the present investigation three commonly available plants were screened namely Emblica officinalis, Saraca indica and Terminalia arjuna for antimicrobial activity against four Multi-Drug Resistant MDR strains, namely Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Staphylococcus aureus.
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Conclusion & Impact:Further study on purification of active ingredient and their efficacy in controlling MDR is in progress.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Emblica officinalis · Saraca indica · Terminalia arjuna

Abstract

Plant based antimicrobials represent a vast untapped source of medicines and has enormous therapeutic potential. In the present investigation three commonly available plants were screened namely Emblica officinalis, Saraca indica and Terminalia arjuna for antimicrobial activity against four Multi-Drug Resistant MDR strains, namely Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Staphylococcus aureus. Antimicrobial activity of aqueous and ethanol extracts was determined with the help of agar well diffusion method. Result showed that the ethanolic extract appears to have more antimicrobial activity in comparison to the aqueous extract and leaf extract of E.officinalis showed maximum antimicrobial activity in comparison to the leaf extracts of S.indica and T.arjuna. This study highlights that crude extracts of E. officinalis, S. indica and T. arjuna are effective against MDR pathogens. Further study on purification of active ingredient and their efficacy in controlling MDR is in progress.

Özet

B itki temelli antimikrobiyal kullanılmayan muazzam bir ilaç kaynağını temsil eder ve ciddi anlamda tedavi potansiyali vardır. Bu çalışmada, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli ve Staphylococcus aureus olarak adlandırılan Çoklu-İlaç’a Dirençli dört yapıya karşı Emblica officinalis, Saraca indica ve Terminalia arjuna antimikrobiyal aktivitesi gözlendi. Sulu çözelti ve etanol özütlerinin antimikrobiyal aktivitesi katı difüzyon yöntemiyle belirlendi. Sonuçlar, etanol özütlerin sulu çözeltilere göre ve E.officinalis yaprak özütlerinin S.indica ve T.arjuna yaprak özütlerine göre daha çok antimiktobiyal aktivite gösterdiklerini ortaya koymuştur. Bu çalışmada, işlenmemiş E. officinalis, S. indica ve T. arjuna özütlerinin MDR patojenlerine karşı etkisi vurgulanmaktadır. Aktif bileşenlerin saflaştırılması ve MDR kontrolündeki etkileri ile ilgili başka çalışmalar devam etmektedir

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Cite This Article

GUPTA, R., RAMTEKE, P. W. (2011). Antimicrobial activity of Emblica officinalis, Saraca indica and Terminalia arjuna against Multi-Drug Resistant MDR Bacterial Pathogens. Hacettepe Journal of Biology and Chemistry, Cilt: 39 - Sayı: 4, 435–437. https://ajindex.com/articles/256070

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