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Journals / El-Cezeri / 2016 / Cilt: 3 - Sayı: 2

Radiation Effects on Lamotrigine and Flourbiprofen: an EPR study

Radyasyonun Lamotrijin ve Flurbiprofen Üzerine Etkisinin EPR Çalışması

Şemsettin OSMANOĞLU
Farhad Hamadameen HAMADAMEEN
Ali YEŞİL
Kerem SÜTÇÜ
Yunus Emre OSMANOĞLU
Journal
El-Cezeri
Pages
281–286
Publication Date
2016-05-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, the free radicals were appeared to be stable at room temperature for more than two months.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Electron paramagnetic resonance (EPR) spectroscopy was used to determine the gamma radiation damages in Lamotrigine and Flurbiprofen.The free radicals produced in the samples were interpreted in terms of some type of alkyl and amine radical fragments.
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Key Findings & Data:The g values and hyperfine structure constants of the radicals were determined and the spectra were computer simulated.
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Conclusion & Impact:In this study, the free radicals were appeared to be stable at room temperature for more than two months.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:EPR · ilaç · serbest radikal

Abstract

Electron paramagnetic resonance (EPR) spectroscopy was used to determine the gamma radiation damages in Lamotrigine and Flurbiprofen.The free radicals produced in the samples were interpreted in terms of some type of alkyl and amine radical fragments. The g values and hyperfine structure constants of the radicals were determined and the spectra were computer simulated. In this study, the free radicals were appeared to be stable at room temperature for more than two months.

Özet

Bu çalışmada gama radyasyonun Lamotrijin ve Flurbiprofen’de oluşturduğu hasarları belirlemek için Elektron Paramanyetik Rezonans Spektroskopisi kullanıldı. Örneklerde oluşan serbest radikallerin bazı alkil ve amin türü radikaller olabileceği şeklinde yorumlandı. Radikallerin g değerleri ve aşırı ince yapı sabitleri belirlendi. Örneklerin spektrum simülasyonları bilgisayar kullanılarak gerçekleştirildi. Örneklerde oluşan serbest radikallerin oda sıcaklığında iki aydan daha fazla kararlı olduğu ortaya çıktı

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Cite This Article

OSMANOĞLU, Ş., HAMADAMEEN, F. H., YEŞİL, A., SÜTÇÜ, K., OSMANOĞLU, Y. E. (2016). Radiation Effects on Lamotrigine and Flourbiprofen: an EPR study. El-Cezeri, Cilt: 3 - Sayı: 2, 281–286. https://ajindex.com/articles/252461

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