SavedAdd your journal

Journals / Journal of Istanbul Veterinary Sciences / 2017 / Cilt: 1 - Sayı: 2

Inherited Diseases of Holstein Cattle: Story So Far in Turkey

Kozet AVANUS
Ahmet ALTINEL
Pages
40–46
Publication Date
2017-08-21
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Determining the carrier animals and exclude them from breeding is the only solution for eradication studies of inherited diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Inherited diseases are caused by recessive alleles proceed from increased inbreeding in Holstein cattle population.
📊
Key Findings & Data:The prevalence for carriers of BLAD, DUMPS, CVM, FXID and BC diseases were reported highest in Denmark (21.5%), USA (1.2%), Japan (32.5%), Turkey (18%) and Australia (13%) respectively.
💡
Conclusion & Impact:Determining the carrier animals and exclude them from breeding is the only solution for eradication studies of inherited diseases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Holstein · inherited disease · BLAD

Abstract

Inherited diseases are caused by recessive alleles proceed from increased inbreeding in Holstein cattle population. Bovine leucocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase enzyme (DUMPS), complex vertebral malformation (CVM), factor XI deficiency (FXID) and bovine citrulinaemia (BC) are the most frequent inherited diseases in Holstein cattle population. The prevalence for carriers of BLAD, DUMPS, CVM, FXID and BC diseases were reported highest in Denmark (21.5%), USA (1.2%), Japan (32.5%), Turkey (18%) and Australia (13%) respectively. Moreover the highest prevalence for carriers of BLAD, CVM and FXID were reported as 2.2%, 3.4% and 18% respectively in Turkey so far. Neither DUMPS nor BC carriers were identified in Turkey so far. However further studies are required in order to identify the provinces that have risks for mutant alleles of inherited diseases in Turkey. Determining the carrier animals and exclude them from breeding is the only solution for eradication studies of inherited diseases.

Özet

Inherited diseases are caused by recessive alleles proceed from increased inbreeding in Holstein cattle population. Bovine leucocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase enzyme (DUMPS), complex vertebral malformation (CVM), factor XI deficiency (FXID) and bovine citrulinaemia (BC) are the most frequent inherited diseases in Holstein cattle population. The prevalence for carriers of BLAD, DUMPS, CVM, FXID and BC diseases were reported highest in Denmark (21.5%), USA (1.2%), Japan (32.5%), Turkey (18%) and Australia (13%) respectively. Moreover the highest prevalence for carriers of BLAD, CVM and FXID were reported as 2.2%, 3.4% and 18% respectively in Turkey so far. Neither DUMPS nor BC carriers were identified in Turkey so far. However further studies are required in order to identify the provinces that have risks for mutant alleles of inherited diseases in Turkey. Determining the carrier animals and exclude them from breeding is the only solution for eradication studies of inherited diseases.

🔖

Cite This Article

AVANUS, K., ALTINEL, A. (2017). Inherited Diseases of Holstein Cattle: Story So Far in Turkey. Journal of Istanbul Veterinary Sciences, Cilt: 1 - Sayı: 2, 40–46. https://ajindex.com/articles/229720

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Adamov, N., Mitrov, D., Esmerov, I., & Dovc, P. (2014). Detection of recessive mutations (BLAD and CVM ) in Holstein-Friesian cattle population in Republic of Macedonia. Macedonian Veterinary Review, 37(1), 61–68. http://doi.org/10.14432/j.macvetrev.2013.11.005
  2. Agerholm, J. S., Bendixen, C., Andersen, O., & Arnbjer, J. (2001). Complex vertebral malformation in Holstein calves. J Vet Diagn Invest, 13,283–289.
  3. Agerholm, J. S., Bendixen, C., Arnbjerg, J., & Andersen, O. (2004). Morphological variation of “complex vertebral malformation” in Holstein calves. J Vet Diagn Invest, 16,548-553.
  4. Akyüz, B. (2013). Türkiye’deki iki farkli işletmede yetiştirilen Holştayn boğalarda faktör XI yetmezliği (FXID) allel frekansının belirlenmesi. Kafkas Universitesi Veteriner Fakultesi Dergisi, 19(1), 127–131. http://doi.org/10.9775/kvfd.2012.7354
  5. Akyüz, B., Bayram, D., Ertuğrul, O., & İşcan, K. M. (2008). Türkiye’de yetiştirilen Holştayn ve bazı yerli sığır ırklarında Citrullinemia allelinin belirlenmesi. J Fac Vet Med Univ Erciyes, 5(1), 17–20.
  6. Akyüz, B., & Ertuğrul, O. (2006). Detection of bovine leukocyte adhesion deficiency (BLAD) in Turkish native and Holstein cattle. Acta Veterinaria Hungarica, 54(2), 173–178. http://doi.org/10.1556/AVet.54.2006.2.4
  7. Akyüz, B., & Ertuğrul, O. (2008). Türkiye’de Holştayn ve yerli sığırlarda üridin monofosfat senteaz eksikliğinin (DUMPS) belirlenmesi. Ankara Üniv Vet Fak Derg, 55, 57–60.
  8. Akyüz, B., & Kul, B. Ç. (2009). Türkiye’deki holştayn ineklerde üridin monofosfat senteaz eksikliğinin (DUMPS) belirlenmesi. Ankara Üniv Vet Fak Derg, 56, 231–232.
  9. Akyüz, B, Sarıözkan, S, Bayram D: Factor XI mutation in normally fertile and repeat breeding Holstein cows in the Middle Anatolian region of Turkey: A financial approach. Anim Prod Sci, 52, 1042-1045, 2012.
  10. Akyüz, B., Sarıözkan, S., & Bayram, D. (2015). The prevalence of BLAD and comparison of some production parameters in carrier and non-carrier Holstein cows in Kayseri province, Turkey. J Fac Vet Med Univ Erciyes, 12(1), 31–35.
  11. Avanus, K., & Altınel, A. (2016a). Identification of allele frequency of factor XI deficiency (FXID) in Holstein cows reared in Thrace region of Turkey. J. Fac. Vet. Med. Istanbul Univ, 42(2), 190–193. http://doi.org/10.16988/iuvfd.2016.53309
  12. Avanus, K., & Altınel, A. (2016b, June, 1-4). Identification of Allele Frequency of SLC35A3 Gene Causing Complex Vertebral Malformation (CVM) in Holstein Cows Reared in Thrace Region and Comparing Three Methods Use in Determination