Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2008 / Cilt: 14 - Sayı: 2

Endometrial seröz karsinomun servikovajinal yayma bulguları: Olgu sunumu

Cervicovaginal smear findings of endometrial serous carcinoma: A case report

Pages
132–135
DOI
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⚡ TL;DR(Too Long; Didn't Read)

This may be related with advanced stage and/or aggressive features of the neoplastic process.

📌 3 Key Takeaways

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Objective & Hypothesis:An endometrial serous carcinoma case which is a variant of endometrial carcinoma exhibiting an agressive course that has been detected by cervicovaginal smear, is presented in this report in light of the datas of the related literature.
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Key Findings & Data:No particular sign has been observed during the gynecological examination of the 77-year-old patient who applied to university hospital with the complaints of vaginal discharge and perineal pruritus.
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Conclusion & Impact:This may be related with advanced stage and/or aggressive features of the neoplastic process.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

An endometrial serous carcinoma case which is a variant of endometrial carcinoma exhibiting an agressive course that has been detected by cervicovaginal smear, is presented in this report in light of the datas of the related literature. No particular sign has been observed during the gynecological examination of the 77-year-old patient who applied to university hospital with the complaints of vaginal discharge and perineal pruritus. Cervicovaginal smear showed atypical glandular cells, exhibiting seldom bare nuclei and papillary clusters in most of the areas with a necrotic background. By the help of those cytopathological findings, the diagnosis was “Epithelial cell abnormality: atypical glandular cells (AGC) in favour of neoplasia and atypical squamous cells of undetermined significance (ASCUS) and due to “possiblity of an adenocarcinoma”, cervical and/or endometrial biopsy was recommended. The result of the endometrial biopsy was reported as “serous papillary adenocarcinoma”. Postoperatively, examination of hysterectomy material revealed an infiltration of “endometrial serous carcinoma” extending towards cervix, myometrium, and serosa, and full filling the endometrial cavity. The case, regarded as Stage IV died on postoperative 13th day. Although cervicovaginal smear generally is not a sensitive screening test for endometrial carcinomas, it played an important role in determining serous carcinoma. This may be related with advanced stage and/or aggressive features of the neoplastic process.

Özet

Servikovajinal yaymada saptadığımız endometrial karsinomun agresif klinik seyir gösteren varyantı olan endometrial seröz karsinom olgusu, literatür bilgileri ışığında sunulmaktadır. Vajinal akıntı ve perineal kaşıntı şikayetiyle hastanemize başvuran 77 yaşındaki hastanın jinekolojik muayenesinde bir özellik izlenmemiştir. Servikovajinal yaymada; nekrotik zeminde, yer yer çıplak nükleuslu, çoğu alanda papiller kümeler oluşturan atipik glandüler hücreler izlendi. Bu sitopatolojik bulgularla "Epitelyal hücre anomalisi: atipik glandüler hücreler (AGC), neoplazi lehine ve önemi belirlenemeyen atipik skua-möz hücreler (ASCUS) tanısı verildi ve "olası adenokarsinom" nedeniyle olguya servikal ve/veya endometrial biyopsi önerildi. Endometrial biyopsi sonucu "seröz papiller adenokarsinom"olarak rapor edildi. Operasyon sonrası histerektomi materyalinde; endometrial kaviteyi tamamen dolduran, servikse, miyo-metriuma ve serozaya doğru uzanım gösteren "endometrial seröz karsinom" infiltrasyonu gözlendi. Evre-İV olarak kabul edilen olgu, postoperatif 13. günde eksitus olmuştur. Servikovajinal yayma genel olarak endometrial karsinomlar için duyarlı bir tarama testi olmamasına rağmen seröz karsinom olgusunun saptanmasında önemli rol oynamıştır. Bu durum neoplastik sürecin ileri evrede olmasına ve/veya agresif niteliğine bağlanabilir.

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Cite This Article

BARUT, F., ÖZDAMAR, Ş. O., BARUT, A., BAYAR, Ü., BEKTAŞ, S., BAHADIR, B., GÜN, D. B. (2008). Endometrial seröz karsinomun servikovajinal yayma bulguları: Olgu sunumu. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 14 - Sayı: 2, 132–135. https://ajindex.com/articles/227714

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References (1)

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