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Journals / Glokom Katarakt / 2016 / Cilt: 11 - Sayı: 2

Optic Nerve Head Topographic Measurements and Retinal Nerve Fiber Layer Thickness in Patients with Physiological Macrodiscs, Normal and Glaucomatous Optic Discs

Fizyolojik Olarak Büyük, Normal ve Glokomatöz Optik Disklerde, Optik Disk Topografisi ve Retinal Sinir Lifi Tabakası Kalınlık Ölçümleri

Funda Ebru ÖNMEZ
Banu ŞATANA
Çiğdem ALTAN
Ömer Faruk YILMAZ
Pages
113–117
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We suggest that these 2 OCT parameters can help to differentiate a healthy macrodisc from a glaucomatous optic disc.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the parameters of optic nerve head (ONH) and retinal nerve fiber layer (RNFL) in healthy patients with large optic disc area and to compare these parameters with those of the normal and early glaucoma patients.
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Key Findings & Data:Material and Methods: Ninety two eyes with physiological macrodiscs (PM), age-matched 92 eyes with normal eyes and 50 eyes with early glaucoma (EG) findings were enrolled.
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Conclusion & Impact:We suggest that these 2 OCT parameters can help to differentiate a healthy macrodisc from a glaucomatous optic disc.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the parameters of optic nerve head (ONH) and retinal nerve fiber layer (RNFL) in healthy patients with large optic disc area and to compare these parameters with those of the normal and early glaucoma patients. Material and Methods: Ninety two eyes with physiological macrodiscs (PM), age-matched 92 eyes with normal eyes and 50 eyes with early glaucoma (EG) findings were enrolled. After a complete ophthalmic evaluation, measurement of optic nerve head parameters and RNFL thickness using OCT was performed in all subjects. Optic disc areas larger than 2.80 mm2 were accepted as macrodiscs. All OCT parameters were compared between normal-sized discs and macrodiscs. Central corneal thickness, intra ocular pressure and axial length measurements were found to be similar between 3 groups.Results: Mean optic disc area of PM and EG were similar and larger than the control group. Rim area of EG group was thinner than the other groups (p=0.022, p=0.0001). Also, EG group had larger horizontal cup disc ratio, vertical cup disc ratio and cup disc area ratio (p>0.001). Average,superior and inferior RNFL thicknesses were thinner in the EG group (p<0.05).Conclusion: Macrodisc may have a macrocup and should not be misdiagnosed as glaucoma. The present study showed that macrodiscs are identical to normal-sized discs in terms of rim area and RNFL thickness. We suggest that these 2 OCT parameters can help to differentiate a healthy macrodisc from a glaucomatous optic disc.

Özet

Amaç: Geniş optik diske sahip sağlıklı gözlerde optik sinir başı(OSB) parametrelerinin ve retina sinir lifi tabakası (RSLT) ölçümlerinin incelenmesi ve bu parametrelerin erken glokoma sahip hastalarla ve normal popülasyonla karşılaştırılması.Gereç ve Yöntem: Fizyolojik makrodiske sahip 92 göz, yaş uyumlu 92 normal kontrol olguları ve erken glokomatöz optik sinir başı hasarı olan 50 göz çalışmaya dahil edildi. Tüm hastalara genel oftalmolojik muayene yapıldıktan sonra Stratus OCT ile OSB ve RSLT ölçümü yapıldı. Disk alanı 2.80 mm2'nin üstü büyük disk olarak kabul edildi. Tüm OKT parametreleri 3 grup arasında kıyaslandı. Bulgular: Normal grubunun OD alanı ortalamaları diğer gruplardan istatistiksel olarak anlamlı derecede düşük bulunmuş (p=0.0001), sağlıklı makrodisk ve glokom grupları arasında istatistiksel olarak anlamlı farklılık gözlenmemiştir (p=0.705). Glokom grubunun rim alanı ortalamaları diğer 2 gruptan istatistiksel olarak anlamlı derecede düşük bulundu (p=0.022, p=0.0001). Glokom grubunda çukurlaşma alanının (CA), horizontal çukurluk disk oranı(HCDR), vertikal çukurluk disk oranı (VCDR), çukurlukdisk alanı oranı (CDAR) kontrol ve sağlıklı makrodisk grubuna göre anlamlı derecede yüksek bulundu. (p 0.05).Sonuç: Büyük diskler geniş çukurluğa sahip olabilirler ve yanlış glokom tanısına neden olabilirler. Bu çalışma, makrodisklerin rim alanı ve RSLT kalınlığı açısından normal disklere benzediğini göstermiştir. Fizyolojik makrodiskleri, glokomatöz optik nöropatiden ayırımını sağlayan parametreler ise geniş rim alanı, düşük çukurlaşma ve çukurlaşma/disk oranları idi

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Cite This Article

ÖNMEZ, F. E., ŞATANA, B., ALTAN, Ç., YILMAZ, Ö. F. (2016). Optic Nerve Head Topographic Measurements and Retinal Nerve Fiber Layer Thickness in Patients with Physiological Macrodiscs, Normal and Glaucomatous Optic Discs. Glokom Katarakt, Cilt: 11 - Sayı: 2, 113–117. https://ajindex.com/articles/226908

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