Acute bilateral angle closure glaucoma secondary to topiramate use

Key Findings & Data:Patient had no prior history of glaucoma and/or any other ocular abnormalities but had a history of secondary generalized epilepsy and was started with topiramate acetate 10 days prior to admission.

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Conclusion & Impact:Due to the potential ophthalmic side effects of topiramate, patients should be warned prior to drug initiation.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Kadın · Orta yaşlı · Glokom

Abstract

A case, which presents with acute bilateral angle-closure glaucoma and acute myopia, was seen at our clinic. Patient had no prior history of glaucoma and/or any other ocular abnormalities but had a history of secondary generalized epilepsy and was started with topiramate acetate 10 days prior to admission. Patient’s signs and symptoms responded well to topiramate discontinuation, topical and systemic anti glaucomatous medications and topical cycloplegic agents. In the follow-up period, visual acuity, intraocular pressure, gonioscopic and A-scan ultrasonographic findings returned to normal. Due to the potential ophthalmic side effects of topiramate, patients should be warned prior to drug initiation.

Özet

Bilateral açı kapanması glokomu ve akut miyopi gelişen olgu kliniğimize başvurdu. Hastanın özgeçmişinde glokom ve/veya başka oküler sorun bulunmamasına karşın, ikincil jeneralize epilepsi nedeniyle 10 gün önce topiramat asetat tedavisi başlanmıştı. Topiramat tedavisi kesilen ve topikal ve sistemik antiglokomatöz ajanlar ile topikal sikloplejik tedavisi başlanan hastanın şikayet ve semptomları kayboldu. Hastanın takiplerinde, görme keskinliği, göz içi basıncı, Ascan biometrik ve gonyoskopik bulguları normale döndü. Topiramatın bu olası oftalmik yan etkileri nedeniyle, hastalar ilaç öncesinde bilgilendirilmeli ve uyarılmalıdır.

Keywords

Kadın Orta yaşlı Glokom dar-açılı Female Middle Aged Glaucoma Angle-Closure

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Cite This Article

ALTIPARMAK, U. E., HAMURCU, A. G., YILMAZ, İ. A., ŞATANA, S. B., DUMAN, S. (2007). Acute bilateral angle closure glaucoma secondary to topiramate use. Glokom Katarakt, Cilt: 2 - Sayı: 1, 67–69. https://ajindex.com/articles/226658

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