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Journals / Glokom Katarakt / 2008 / Cilt: 3 - Sayı: 3

Evaluation of the relationship between retinal nerve fiber layer thickness measured by optical coherence tomography and central corneal thickness in normal tension and primary open angle glaucoma

Normal basınçlı ve primer açık açılı glokomda optik koherens tomografi ile ölçülen retina sinir lifi tabakası kalınlığı ve santral korneal kalınlık arasındaki ilişkinin değerlendirilmesi

Zeynep AKTAŞ
Bahçeci Umut DİNÇ
Merih ÖNOL
Berati HASANREİSOĞLU
Pages
147–152
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This correlation seems to be localized in NTG patients whereas more diffuse in POAG patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the relationship between central corneal thickness (CCT) and retinal nerve fiber layer (RNFL) thickness measured with optic coherence tomography (OCT) in patients with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG).
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Key Findings & Data:Materials and Methods: Records of total one hundred and eighty eight eyes of 188 patients with NTG, POAG and healthy controls were included in the study.
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Conclusion & Impact:This correlation seems to be localized in NTG patients whereas more diffuse in POAG patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Glokom · Glokom · açık-açılı

Abstract

Purpose: To evaluate the relationship between central corneal thickness (CCT) and retinal nerve fiber layer (RNFL) thickness measured with optic coherence tomography (OCT) in patients with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Materials and Methods: Records of total one hundred and eighty eight eyes of 188 patients with NTG, POAG and healthy controls were included in the study. Complete ophthalmologic examination, intraocular pressure (IOP) measurement with Goldman applanation tonometry, CCT measurement, RNFL analysis and automated perimetry were performed in all patients. Patient’s age, refraction, IOP, CCT, RNFL thickness, mean deviation (MD) and pattern standart deviation (PSD) values were recorded. Results: Pattern of RNFL loss was mostly found to be diffuse in both NTG and POAG groups. CCT of NTG patients was significantly lower than that of healthy controls (p=0.001). Correlation between CCT and RNFL thickness was significant at 8, 11, 2 o’clock in POAG group whereas it was significant only at 7 o’clock in NTG group (p= 0.045, p=0.048, p=0.030 and p=0.017; respectively). Conclusion: Distribution of RNFL loss is similar in NTG and POAG. CCT significantly correlates with RNFL thickness measured by OCT in NTG and POAG patients. This correlation seems to be localized in NTG patients whereas more diffuse in POAG patients.

Özet

Amaç: Primer açık açılı glokom (PAAG) ve normal basınçlı glokomu (NBG) olan olgularda optik koherens tomografi (OCT) ile saptanan retina sinir lifi tabakası (RSLT) kalınlığı ve santral korneal kalınlık (SKK) ilişkisinin değerlendirilmesi. Gereç ve Yöntem: PAAG, NBG ve sağlıklı kontrol gözlerinden oluşan toplam 188 olgunun 188 gözü çalışmaya dahil edildi. Tüm olgularda rutin oftalmolojik muayene, Goldman applanasyon tonometresi ile göz içi basıncı (GİB) ve SKK ölçümleri, RSLT analizi, görme alanı muayenesi yapıldı. Olguların yaşı, refraksiyonu, GİB, SKK, tüm kadranlarda ölçülen RSLT, ortalama sapma (MD) ve pattern standart sapma (PSD) değerleri kaydedildi. Bulgular: NBG ve PAAG gruplarında RSLT kaybının çoğunlukla diffüz olduğu saptandı. NBG’lu olgularda ölçülen SKK, sağlıklı kontrol gözlere göre daha düşüktü (p=0.001). SKK ve RSLT kalınlığı arasındaki ilişki, PAAG’lu gözlerde 8, 11 ve 2 kadranlarında anlamlı bulunurken, NBG’lu gözlerde sadece saat 7 kadranında anlamlı idi (sırasıyla; p=0.045, p=0.048, p=0.030, p=0.017). Sonuç: NBG ve PAAG’da RSLT kaybının dağılımı benzerdir. NBG ve PAAG’lu olgularda SKK ve OCT ile ölçülen RSLT kalınlığı arasında anlamlı korelasyon mevcuttur. Bu korelasyon NBG olgularında lokalizeyken, PAAG olgularında daha diffüz gibi görünmektedir.

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Cite This Article

AKTAŞ, Z., DİNÇ, B. U., ÖNOL, M., HASANREİSOĞLU, B. (2008). Evaluation of the relationship between retinal nerve fiber layer thickness measured by optical coherence tomography and central corneal thickness in normal tension and primary open angle glaucoma. Glokom Katarakt, Cilt: 3 - Sayı: 3, 147–152. https://ajindex.com/articles/226636

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