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Journals / Glokom Katarakt / 2009 / Cilt: 4 - Sayı: 2

Glokom ve oküler hipertansiyonda merkezi kornea kalınlığı ve merkezi kornea kalınlığını etkileyen faktörler

Central corneal thickness in glaucoma subgroups and ocular hypertension and the factors affecting central corneal thickness

Emine ŞEN
Alper YAZICI
Ayşe ALTINOL
F. Nur AKSAKAL
Tülay TUNA
KADRİYE UFUK ELGİN
Gültekin KÖKLÜ
Pages
79–83
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

DM and HT did not seem to have a relation with CCT.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the central corneal thickness (CCT) values in Primary Open Angle Glaucoma (POAG), Pseudoexfoliation Glaucoma (PXG), Normal Tension Glaucoma (NTG), Ocular Hypertension (OHT), and normal subjects, and to study the relationship of age, gender, intraocular pressure (IOP) and systemic diseases with CCT.
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Key Findings & Data:Materials and Methods: A total of 286 patients and 50 control subjects were included in our prospective study.
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Conclusion & Impact:DM and HT did not seem to have a relation with CCT.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the central corneal thickness (CCT) values in Primary Open Angle Glaucoma (POAG), Pseudoexfoliation Glaucoma (PXG), Normal Tension Glaucoma (NTG), Ocular Hypertension (OHT), and normal subjects, and to study the relationship of age, gender, intraocular pressure (IOP) and systemic diseases with CCT. Materials and Methods: A total of 286 patients and 50 control subjects were included in our prospective study. All the patients were questioned for family history of glaucoma and presence of systemic diseases. IOP and CCT were measured using Goldmann applanation tonometer and ultrasound pachymeter, respectively Results: Only CCT values of NTG (527.8±21.4 μm) and OHT (578.6±24.1 μm) were statistically significantly different from the values of the control group (545.9±39.3 μm). Age and IOP were found to be statistically important factors those affecting CCT in multivariate analysis. Systemic diseases were found to have no significant effect on CCT values. The NTG group had significantly higher rates of diabetes mellitus, hypertension, and hyperlipidemia, while we found no relationship between migraine and NTG in our cases. The rate of positive family history of glaucoma was found to be significantly higher in OHT patients than other cases and normal subjects. Conclusions: NTG and OHT patients have significantly lower and higher CCT values, respectively. There was a moderate thinning of cornea by ageing. DM and HT did not seem to have a relation with CCT.

Özet

Amaç: Primer açık açılı glokom (PAAG), psödoeksfoliyatif glokom (PXG), normotansif glokom (NTG), oküler hipertansiyon ve kontrol grubundaki merkezi kornea kalınlığı (MKK) değerleri ve yaş, cinsiyet, göz içi basıncı (GİB) ve sistemik hastalıklar ile MKK arasındaki ilişkiyi değerlendirmek. Gereç ve Yöntem: Bu ileriye dönük çalışmaya 286 hasta ve 50 kontrol dahil edildi. Tüm hastalardan aile hikayesi ve sistemik hastalık varlığı sorgulandı. Goldmann aplanasyon tonometresi ile GİB, ultrason pakimetri ile MKK ölçüldü. Bulgular: MKK değerleri yalnızca NTG (527.8±21.4 μm) ve OHT (578.6±24.1 μm) grubunda kontrol grubundan (545.9±39.3 μm) istatistiksel olarak anlamlı farklı bulundu. Multivariate analizde yaş ve GİB, MKK etkileyen faktörler olarak bulundu. Sistemik hastalıkların MKK değerleri üzerinde anlamlı etkisi bulunmadı. Diyabet, hipertansiyon ve hiperlipidemi NTG grubunda anlamlı yüksek idi. Bizim vakalalarımızda migren ve NTG arasında ilişki bulunmadı. Pozitif aile hikayesi oranı diğer glokom grupları ve kontrol grubuna göre OHT grubunda anlamlı yüksekti. Tartışma: MKK değerleri NTG grubunda anlamlı düşük, OHT grubunda ise yüksek bulundu. Yaşla beraber korneanın orta derecede inceldiği saptandı. Diyabet ve hipertansiyonun MKK ile ilişkisi bulunmadı

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Cite This Article

ŞEN, E., YAZICI, A., ALTINOL, A., AKSAKAL, F. N., TUNA, T., ELGİN, K. U., KÖKLÜ, G. (2009). Glokom ve oküler hipertansiyonda merkezi kornea kalınlığı ve merkezi kornea kalınlığını etkileyen faktörler. Glokom Katarakt, Cilt: 4 - Sayı: 2, 79–83. https://ajindex.com/articles/226587

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