Journals / Glokom Katarakt / 2010 / Cilt: 5 - Sayı: 4

Retinal nerve fiber layer thickness measurement using optical coherence tomography in healthy children

Sağlıklı çocuklarda optik kohorens tomografi ile retina sinir lifi tabakası kalınlığı ölçümü

Pages
218–222
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The correlations found between RNFL thickness with AL and refraction should be kept in mind by clinicians for correct diagnosis and patient follow-up.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To assess retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (StratusOCT III) in healthy children who do not have any ocular pathology except refractive errors and to investigate the influence of various factors.
📊
Key Findings & Data:Materials and Methods: Cycloplegic refraction was measured using an autorefractometer (SORF), axial length was measured (AL) using optical biometry (IOL master), and RNFL thickness was measured using Stratus OCT III “fast scan” mode in 120 children (60 girls and 60 boys).
💡
Conclusion & Impact:The correlations found between RNFL thickness with AL and refraction should be kept in mind by clinicians for correct diagnosis and patient follow-up.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To assess retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (StratusOCT III) in healthy children who do not have any ocular pathology except refractive errors and to investigate the influence of various factors. Materials and Methods: Cycloplegic refraction was measured using an autorefractometer (SORF), axial length was measured (AL) using optical biometry (IOL master), and RNFL thickness was measured using Stratus OCT III “fast scan” mode in 120 children (60 girls and 60 boys). Results: Mean age of the subjects was 10.7±3.1 (5-16) years. Average AL was 22.91±1.17 mm (19.96-27.13 mm) in the right eyes and 22.82±1.17 mm (19.87-27.09 mm) in the left eyes. Mean SORF values were +1.36±2.24 D (-7.75-+8.25 D) in the right eyes and +1.56±2.33 D (-5.25-+8.50 D) in the left eyes. Mean RNFL thickness was 105.6±9.6 μm (72.22-129.25 μm) and 104.4±9.8 μm (78.97-127.34 μm) respectively in the right and left eyes. There was a statistically significant correlation between AL and RNFL thickness (right eye r=-0.33, p=0.001, left eye r=-0.30, p=0.001), while there was a significant positive correlation between SORF and RNFL thickness (right eye r=0.34, p=0.001, left eye r=0.25, p=0.005). Conclusion: Peripapillary RNFL thickness measurements in children do not seem to be different from those obtained from adults and are not affected by age or gender. The correlations found between RNFL thickness with AL and refraction should be kept in mind by clinicians for correct diagnosis and patient follow-up.

Özet

Amaç: Kırma kusuru dışında oküler patolojisi olmayan sağlıklı çocuklarda optik koherens tomografi (OKT) cihazı kullanılarak retina sinir lifi tabakası (RSLT) kalınlığının ölçülmesi ve farklı parametrelerin etkisinin incelenmesi. Gereç ve Yöntem: Çalışmaya alınan 120 çocuğunun (60 kız, 60 erkek) sikloplejik damla sonrası otorefraktometre ile refraksiyon (SORF) değerleri, optik biyometri (İOL master) kullanılarak aksiyel uzunlukları (AU) ve Stratus OKT III cihazında “hızlı tarama” modu ile RSLT kalınlık değerleri belirlendi. Bulgular: Olguların ortalama yaşı 10.7±3.1 (5-16) yıldı. AU sağ gözlerde 22.91±1.17 mm (19.96-27.13 mm), sol gözlerde 22.82±1.17 mm (19.87-27.09 mm) idi. Ortalama SORF sağ gözlerde +1.36±2.24 D (-7.75 ile +8.25 D arasında), sol gözlerde +1.56±2.33 D (-5.25 ile +8.50 D arasında) olarak ölçüldü. Ortalama RSLT kalınlığı sağ gözlerde 105.6±9.6 μm (72.22-129.25 μm), sol gözlerde ise 104.4±9.8 μm (78.97-127.34 μm) ölçüldü. Yaş ve cinsiyet ile RSLT kalınlığı arasında anlamlı ilişki saptanmadı. Ortalama RSLT kalınlığı ile AU arasında istatistiksel olarak anlamlı negatif korelasyon (sağ göz r=-0.33, p=0.001, sol göz r=-0.30, p=0.001), SORF arasında anlamlı pozitif korelasyon saptandı (sağ göz r=0.34, p=0.001, sol göz r=0.25, p=0.005). Sonuç: Çocuklardaki peripapillar RSLT kalınlığı erişkinlerdeki değerlerden çok farklı olmayıp yaş ve cinsiyetten etkilenmemektedir. AU ve refraksiyon ile RSLT kalınlığı arasında saptanan korelasyonlar doğru teşhis ve hasta takibi için klinik olarak göz önünde tutulmalıdır.

🔖

Cite This Article

PEHLİVANLIOĞLU, S., AKAR, S., GÖKYİĞİT, B., EREN, A., BAYRAKTAR, Ş., YILMAZ, Ö. F. (2010). Retinal nerve fiber layer thickness measurement using optical coherence tomography in healthy children. Glokom Katarakt, Cilt: 5 - Sayı: 4, 218–222. https://ajindex.com/articles/226543

References (17)

  1. Aydın A, Bilge AH.: Optik koherens tomografinin glokomda yeri. Glo-Kat. 2007
  2. Yen MY, Cheng CY, Wang AG.: Retinal nerve fiber layer thickness in unilateral amblyopia. Invest Ophthalmol Vis Sci. 2004
  3. Salchow DJ, Oleynikov YS, Chiang MF, et al.: Retinal nerve fiber layer thickness in normal children measured with optical coherence tomography. Ophthalmology. 2006
  4. ! 13:786-791. 4.Budenz DL, Anderson DR, Varma R, et al.: Determinants of normal retinal nerve fiber layer thickness measured by Stratus OCT. Ophthalmology. 2007
  5. Wang XY, Huynh SC, Burlutsky G, et al.: Reproducibility of and effect of magnification on optical coherence tomography measurements in children. Am J Ophthalmol. 2007
  6. Kashiwagi K,Tamura M, Abe K, et al.:The influence of age, gender, refractive error and optic size on the optic disk configuration in Japanese normal eyes. Acta Ophthalmol Scand. 2000
  7. Varma R, Bazzaz S, Lai M.: Optical tomography-measured retinal nerve fiber layer thickness in normal Latinos. Invest Ophthalmol Vis Sci. 2003
  8. Dichtl A, Jonas JB, Naumann GO.: Retinal nerve fiber layer thickness in human eyes. Graefes Arch Clin Exp Ophthalmol. 1999
  9. 9Gupta G, Donahue JFJ You T.: Profile of the Retina by Optical Coherence Tomography in the Pediatric Age Group. Am J Ophthalmol. 2007
  10. HuynH SC, Wang XY, Burlutsky G, et al.: Symmetry of optical co-, herence tomography retinal measurements in young children. Am J Ophthalmol. 2007
  11. El-Dairi MA, Asrani SG, et al.: Optical coherence tomography in -, the eyes of normal children. Arch Ophthalmol. 2009
  12. Kee SY, Lee SY, Lee YC.: Thicknesses of the fovea and retinal nerve fiber layer in ambliyopic and normal eyes in children. Korean J Ophthalmol. 2006
  13. Altintas O, Yüksel N, Özkan B, et al.: Thickness of the retinal nerve fiber layer, maculdr thickness, and macular volume in patients with strabismic amblyopia. J Pediatr Ophthalmol Strabismus. 2005
  14. Repka MX, Kraker RT, Tamkins SM, et al.: Retinal nerve fiber layer thickness in amblyopic Eyes. Am J Ophthalmol. 2006
  15. Salchow DJ, Oleynikov YS, Chiang MF, et al.: Retinal nerve fiber layer thickness in normal children measured with optical coherence tomography. Ophthalmology. 2006
  16. Alamouti B, Funk J.: Retinal thickness decreases with age an OCT study. Br J Ophthalmol. 2003
  17. Balazsi AG, Roo