Recurrent herpetic keratouveitis and scleritis: a rare case report

We present a rare combination of stromal keratitis, non-necrotizing scleritis, iridocyclitis, glaucoma, and endotelitis in a patient with recurrent herpetic eye disease.

📌 3 Key Takeaways

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Objective & Hypothesis:Herpes virus type 1 eye infections are often caused by the activation of latent viruses in the trigeminal ganglion.

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Key Findings & Data:Topical cyclosporine A can be used as an immunomodulatory agent both to taper topical corticosteroids and also in the treatment of dry eye symptoms accompanying decreased corneal sensitivity.

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Conclusion & Impact:We present a rare combination of stromal keratitis, non-necrotizing scleritis, iridocyclitis, glaucoma, and endotelitis in a patient with recurrent herpetic eye disease.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Herpes virus type 1 eye infections are often caused by the activation of latent viruses in the trigeminal ganglion. The most common forms of relapses are stromal keratitis and iridocyclitis, but blepharitis, conjunctivitis, scleritis, epithelial keratitis, and endotelitis also can be seen. Topical and systemic antiviral agents and topical corticosteroids are widely used in herpetic eye involvement. A low dose of systemic acyclovir was found to be efficient in the prevention of recurrence of all forms of herpes simplex virus eye diseases. Topical cyclosporine A can be used as an immunomodulatory agent both to taper topical corticosteroids and also in the treatment of dry eye symptoms accompanying decreased corneal sensitivity. We present a rare combination of stromal keratitis, non-necrotizing scleritis, iridocyclitis, glaucoma, and endotelitis in a patient with recurrent herpetic eye disease.

Özet

Herpes virüs Tip 1 göz enfeksiyonları sıklıkla trigeminal gangliondaki latent virüslerin aktivasyonu sonucu meydana gelmektedir. Nüksler en sık stromal keratit ve iridosiklit şeklinde olsa da blefarit, konjonktivit, sklerit, epitelyal keratit, stromal keratit, endotelit veya iridosiklit de görülebilmektedir. Herpetik göz tutulumunda topikal ve sistemik antivirallerle topikal kortikosteroidler yaygın olarak kullanılan ilaçlardır. Düşük doz sistemik asiklovirin herpes virus göz tutulumunun tüm formlarında nüksleri başarılı şekilde azalttığı gösterilmiştir. Topikal siklosporin A gerek topikal kortikosteroid dozunu azaltmak ve gerekse ileri korneal hassasiyet kaybıyla seyreden kuru göz semptomlarını azaltmak için tedaviye eklenebilir. Biz stromal keratit, nekrotizan olmayan sklerit, glokom, endotelit ve iridosiklit bulgularının tümünün bir arada olduğu tekrarlayan herpetik keratitli nadir bir olguyu sunuyoruz.

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Cite This Article

CİNGÜ, A. K., ŞAHİN, A., ŞAHİN, M., ÇINAR, Y., ARI, Ş., ÇAÇA, İ. (2011). Recurrent herpetic keratouveitis and scleritis: a rare case report. Glokom Katarakt, Cilt: 6 - Sayı: 2, 132–134. https://ajindex.com/articles/226522

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