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Journals / Glokom Katarakt / 2013 / Cilt: 8 - Sayı: 2

Fakoemülsifikasyon sonrası göz içi basıncı artışı tedavisinde brimonidin-timolol ile dorzolamide-timolol’ün karşılaştırılması

Brimonidine-timolol versus dorzolamide- timolol for treatment of ıntraocular pressure spikes after phacoemulsification

Veysi ÖNER
Mehmet Fuat ALAKUŞ
Mehmet TAŞ
Yalçın İŞÇAN
Kemal TÜRKYILMAZ
Mustafa DURMUŞ
Pages
111–115
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our study has demonstrated that both FCDT and FCBT, each one drop administered immediately after proce- dure, were effective and both had similar efficacy for preventing IOP elevation after phacoemulsification surgery.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To compare the efficacies of fixed combination dorzolamide-timolol (FCDT) and fixed combination brimonidine- timolol (FCBT) for preventing intraocular pressure (IOP) spikes after phacoemulsification surgery.
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Key Findings & Data:Materials and Methods: One hundred and fifty eyes of 150 patients undergoing phacoemulsification surgery were enrolled in this study.
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Conclusion & Impact:Conclusion: Our study has demonstrated that both FCDT and FCBT, each one drop administered immediately after proce- dure, were effective and both had similar efficacy for preventing IOP elevation after phacoemulsification surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To compare the efficacies of fixed combination dorzolamide-timolol (FCDT) and fixed combination brimonidine- timolol (FCBT) for preventing intraocular pressure (IOP) spikes after phacoemulsification surgery. Materials and Methods: One hundred and fifty eyes of 150 patients undergoing phacoemulsification surgery were enrolled in this study. Patients were randomly divided preoperatively into three groups according to the drug that instilled immedi- ately after surgery; FCDT group that receiving one drop of FCDT, FCBT group that receiving one drop of FCBT and control group that receiving one drop of artificial tear. IOP was recorded immediately before surgery (baseline), at the 6th hour, 24th hour and 7th day postoperatively. Results: Mean IOP levels were significantly lower in the treatment groups than in the control group at the 6th and 24th hours (both p<0.001) after surgery whereas there was no significant difference between the treatment groups during the follow-up period. Conclusion: Our study has demonstrated that both FCDT and FCBT, each one drop administered immediately after proce- dure, were effective and both had similar efficacy for preventing IOP elevation after phacoemulsification surgery.

Özet

Amaç: Fakoemülsifikasyon cerrahisi sonrası göz içi basıncı (GİB) yükselmesinin önlenmesinde dorzolamide-timolol sabit kombinasyonu (DTSK) ile brimonidine-timolol sabit kombinasyonu (BTSK)’nun etkinliklerinin karşılaştırılması. Gereç ve Yöntem: Fakoemülsifikasyon cerrahisine giden 150 hastanın 150 gözü bu çalışmaya dahil edildi. Hastalar cerra- hiden hemen sonra damlatılan damlalara göre rastgele üç gruba ayrıldı; DTSK grubuna 1 damla DTSK, BTSK grubuna 1 damla BTSK ve kontrol grubuna 1 damla suni gözyaşı damlatıldı. GİB her hasta için ameliyattan hemen önce ve ameliyat sonrası 6. saat, 24. saat ve 7. günlerde ölçüldü. Bulgular: Ortalama GİB değerleri 6. ve 24. saatlerde DTSK ve BTSK gruplarında kontrol grubuna göre anlamlı derecede düşüktü (p<0.001). Ancak her iki tedavi grubunda takip süresi boyunca anlamlı bir fark yoktu. Sonuç: Bu çalışma, işlem sonrası damlatılan bir damla DTSK veya BTSK’nın her ikisinin de fakoemulsifiakasyon cerrahisi sonrası GİB artışının önlenmesinde etkin olduğu ve benzer etkiye sahip olduklarını gösterdi.

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Cite This Article

ÖNER, V., ALAKUŞ, M. F., TAŞ, M., İŞÇAN, Y., TÜRKYILMAZ, K., DURMUŞ, M. (2013). Fakoemülsifikasyon sonrası göz içi basıncı artışı tedavisinde brimonidin-timolol ile dorzolamide-timolol’ün karşılaştırılması. Glokom Katarakt, Cilt: 8 - Sayı: 2, 111–115. https://ajindex.com/articles/226475

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