The Effect of Supraglottic Airway Insertion on Intraocular Pressure in Rabbits

Objective & Hypothesis:Purpose: To evaluate the changes in intraocular pressure (IOP) in rabbits while under general anesthesia before and after insertion of laryngeal mask airway (LMA), Cobra perilaryngeal airway (Cobra PLA), and V-gel laryngeal mask airway.Materials and Methods: Eighteen New Zealand rabbits weighing between 2.0-3.50 kg were randomized into three groups of LMA, Cobra PLA, and V-gel according to body weight.

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Key Findings & Data:After anesthesia induction with intramuscularly 35 mg/kg ketamine and 5 mg/kg xylazine, intravenous 1 mg/kg rocuronium was used for neuromuscular blockage.

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Conclusion & Impact:Our result needs to be supported with future studies in human

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the changes in intraocular pressure (IOP) in rabbits while under general anesthesia before and after insertion of laryngeal mask airway (LMA), Cobra perilaryngeal airway (Cobra PLA), and V-gel laryngeal mask airway.Materials and Methods: Eighteen New Zealand rabbits weighing between 2.0-3.50 kg were randomized into three groups of LMA, Cobra PLA, and V-gel according to body weight. After anesthesia induction with intramuscularly 35 mg/kg ketamine and 5 mg/kg xylazine, intravenous 1 mg/kg rocuronium was used for neuromuscular blockage. IOP were measured just before insertion of airway devices and at 1., 3., 5., 10. min after insertion of airway devices by Tonopen®. Friedman test were used to determine the statistically significance between the measurements in all groups. A p value <0.05 was considered to be statistically significant.Results: Before the insertion of airway devices the mean IOPs in LMA, Cobra PLA, and V-Gel groups were 8.17±2.64, 8.17±4.45, 9.00±1.67 mmHg, respectively. The mean IOPs at 1.min after insertion of airways were measured 6.00±0.63, 7.50±1.38, 6.83±1.17 mmHg, respectively. The changes of IOPs with the insertion of airways in all groups did not reach statistically significance (p>0.05). Conclusion: LMA, Cobra PLA, and V-Gel were found as easy and fast applicable airway devices in rabbits anesthesia. Insertions of these supraglottic airway devices are not associated with an increased IOP response in rabbits. Our result needs to be supported with future studies in human

Özet

Amaç: Tavşanlarda, genel anestezi altında laringeal maske (LMA), cobra perilaringeal hava yolu (Cobra PLA) ve V-gel laringeal maske uygulamasının öncesi ve sonrasında göz içi basıncı değişikliklerini değerlendirmek.Gereç ve Yöntem: Ağırlıkları 2.0-3.50 kg arasında olan onsekiz Yeni Zelanda Tavşanı vücut ağırlıklarına göre LMA, Cobra PLA ve V-gel grupları olmak üzere üçe ayrıldı. İntramüsküler 35 mg/kg ketamin ve 5 mg/kg ksilazin ile anestezi indüksiyonu sonrasında, intravenöz 1mg/kg rokuronyum noromusküler blokaj için kullanıldı. GİB hava yolu uygulamasından hemen önce ve uyguladıktan sonra 1., 3., 5., 10. dakikalarda Tonopen® ile ölçüldü. Tüm gruplardaki ölçümler arasında istatistiksel anlamlılık için Friedman testi kullanıldı. P değeri 0.05).Sonuç: LMA, Cobra PLA, and V-Gel tavşan anestezisinde kolay ve hızlı uygulanabilir havayolu aracı olarak bulundu. Supraglottik hava yolu araçları tavşanlarda artmış GİB cevabı ile ilişkili değildir. Sonuçlarımızın ilerde insanlarda yapılacak çalışmalarla desteklenmesi gereklidir

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Cite This Article

ERŞAN, İ., GENCER, B., ARIKAN, S., TOMAN, H., KARA, S., ERBAŞ, M., TUFAN, H. A. (2015). The Effect of Supraglottic Airway Insertion on Intraocular Pressure in Rabbits. Glokom Katarakt, Cilt: 10 - Sayı: 4, 260–262. https://ajindex.com/articles/226456

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