Journals / Glokom Katarakt / 2015 / Cilt: 10 - Sayı: 1

Macular Edema After Trabeculectomy Assited With 5-Fluorouracil

Trabekülektomi Sonrası 5-Florourasile Bağlı Gelişen Kistoid Maküla Ödemi

Pages
53–54
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Central macular thickness was measured by optical coherence tomography was 570 µm. 5-FU applied during trabeculectomy was believed to be the cause of cystoid macular edema development

📌 3 Key Takeaways

🎯
Objective & Hypothesis:29 years old female patient without any systemic disease, admitted with vision loss and headaches.
📊
Key Findings & Data:The patient had shallow anterior chamber, BCVA 0.05 (Snellen), intraocular pressure (IOP): 64 mmHg in the first examination.
💡
Conclusion & Impact:Central macular thickness was measured by optical coherence tomography was 570 µm. 5-FU applied during trabeculectomy was believed to be the cause of cystoid macular edema development
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

29 years old female patient without any systemic disease, admitted with vision loss and headaches. The patient had shallow anterior chamber, BCVA 0.05 (Snellen), intraocular pressure (IOP): 64 mmHg in the first examination. After primary narrow angle glaucoma diagnosis, bilateral peripheral iridotomy was performed and topical treatment was given (brinzolamide, timolol and brimonidin). Because of high IOP, trabeculectomy was done and 5-fluorouracil (5-FU) was used during surgery. We observed best corrected visual acuity (BCVA) 0.2, intraocular pressure (IOP): 12 mmHg (without medication) and cystoid macular edema; postoperative examination at 1st month. Central macular thickness was measured by optical coherence tomography was 570 µm. 5-FU applied during trabeculectomy was believed to be the cause of cystoid macular edema development

Özet

Herhangi bir sistemik hastalığı olmayan 29 yaşında kadın hasta az görme ve baş ağrısı şikayetiyle başvurdu. Hastanın ilk muayenesinde ön kamaranın sığlaşmış olduğu, EDGK 0.05 (snellen), GİB'ı 64 mmHg olduğu tespit edildi. Primer dar açılı glokom tanısı konan hastaya bilateral periferik iridotomi yapıldı, topikal brinzolamid, timolol ve brimonidin verildi. GİB yüksek seyretmesi nedeniyle trabekülektomi ameliyatı yapıldı, ameliyat esnasında 5-florourasil (5-FU) kullanıldı. Ameliyat sonrası 1. aydaki muayenesinde EDGK 0.2, GİB:12 mmHg (ilaçsız), ve göz dibi muayenesinde kistoid maküla ödemi geliştiği izlendi. Optik koherens tomografi ile yapılan merkezi maküla kalınlığı ölçümü 570 µm olarak saptandı. Trabekülektomi esnasında uygulanan 5-FU'nun kistoid maküla ödemi gelişimine sebep olduğu düşünüldü

🔖

Cite This Article

DEMİR, M., ŞENSÖZ, H., ŞENDÜL, Y., OLGUN, A. (2015). Macular Edema After Trabeculectomy Assited With 5-Fluorouracil. Glokom Katarakt, Cilt: 10 - Sayı: 1, 53–54. https://ajindex.com/articles/226443

References (5)

  1. Önol M, Tufan H.A. Glokom cerrahisinden sonra yara yeri iyileşme cevabının modülasyonu. Glo-Kat 2006;1:77-3.
  2. Koutsonas A, Remky A, Plange N. Long-term results after trabeculec- tomy with 5-fluorouracil. Ophthalmologe 2013;7. De Fendi LI, Arruda GV, Scott IU, et al. Mitomycin C versus 5-fluorou- racil as an adjunctive treatment for trabeculectomy: a meta-analysis of randomized clinical trials. Clin Experiment Ophthalmol 2013;41:798-806
  3. Olawoye OO, Ashaye AO, Baiyeroju AM, et al. Outcomes of trabeculec- tomy with 5-Fluorouracil at a nigerian tertiary hospital. J Ophthalmic Vis Res 2013;8:126-33.
  4. Matsumoto Y, Fujihara M, Kanamori A, et al. Effect of axial length reduction after trabeculectomy on the development of hypotony macu- lopathy. Jpn J Ophthalmol 2014;7. Liang YB 1, Feng MY, Meng HL, et al. Early efficacy and complications of releasable sutures for trabeculectomy in primary angle-closure glau- coma: a randomized clinical trial. J Glaucoma 2014;23:136-41.
  5. Sesar A, Cavar I, Sesar AP, et al. Macular thickness after glaucoma filtration surgery. Coll Antropol 2013;37:841-5. Blankenship GW. Evaluation of a single intravitreal injection of 5-fluorouracil in vitrectomy cases. Graefes Arch Clin Exp Ophthalmol 1989;227:565-8.