Journals / Gülhane Tıp Dergisi / 2005 / Cilt: 47 - Sayı: 3

Factors affecting mortality in mechanically ventilated patients in the surgical intensive care unit

Mekanik ventilatör desteği gereken cerrahi yoğun bakım hastalarında mortaliteyi etkileyen faktörler

Pages
209–213
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We propose that higher tidal volumes may induce biotrauma and volutrauma by increasing plateau pressures, and also higher SAPS II scores and need for higher levels of fractioned oxygen are indicators of poor prognosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Mechanical ventilation support is one of the most essential applications in the medical and surgical intensive care units (sICU).
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Key Findings & Data:Thirty four patients with a total of 36 mechanical ventilation episodes, who were admitted to sICU during two years period, were included in this study.
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Conclusion & Impact:We propose that higher tidal volumes may induce biotrauma and volutrauma by increasing plateau pressures, and also higher SAPS II scores and need for higher levels of fractioned oxygen are indicators of poor prognosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Solunum · yapay · Ventilatörler

Abstract

Mechanical ventilation support is one of the most essential applications in the medical and surgical intensive care units (sICU). Elderly patients admitted to sICU in the preoperative or postoperative periods may require artificial ventilation especially in order to treat acute respiratory failure. In this study, we aimed to determine the prognostic factors affecting the mortality in mechanically ventilated surgical patients. Thirty four patients with a total of 36 mechanical ventilation episodes, who were admitted to sICU during two years period, were included in this study. Demographic data, diagnosis, surgical procedures, simplified acute physiology scores (SAPS II), causes of respiratory failure, duration of mechanical ventilation, tidal volumes, positive end-expiratory pressure levels, adjusted ventilator modes, fractioned oxygen levels, employed weaning methods, success of weaning and patient survival were collected retrospectively. All data were compared between survivors and non-survivors except for weaning methods. Sixteen patients (44.4%) were discharged form sICU and hospital (Survivor group), whereas twenty patients (55.6%) died (Non-survivor group). In this study tidal volumes, SAPS II scores and lowest fractioned oxygen levels were significantly different between survivors and non-survivors. We propose that higher tidal volumes may induce biotrauma and volutrauma by increasing plateau pressures, and also higher SAPS II scores and need for higher levels of fractioned oxygen are indicators of poor prognosis.

Özet

Mekanik ventilatör desteği, dahili ve cerrahi yoğun bakım ünitelerinin en önemli uygulamalarından birisidir. Cerrahi yoğun bakım ünitelerine kabul edilen yüksek riskli ve düşkün hastalara, cerrahi müdahale öncesi veya sonrası, özellikle akut solunum yetmezliğinin düzeltilmesi amacıyla mekanik ventilasyon gerekebilmektedir. Bu çalışmada, mekanik ventilasyon uyguladığımız hastaların tedavisindeki ventilator yönetimini değerlendirmeyi ve mortaliteyi etkileyen prognostik faktörleri saptamayı amaçladık. İki yıllık süre içinde cerrahi yoğun bakım ünitesine kabul edilerek, mekanik ventilatör desteği uygulanan 34 hastaya ait toplam 36 mekanik ventilasyon uygulaması, çalışmaya dahil edildi. Hastalara ait demografik veriler, tanı, uygulanan cerrahi işlem, basitleştirilmiş akut fizyoloji skoru ("Simplified acute physiology score-II", "SAPS-II"), mekanik ventilasyon gerektiren solunum yetmezliği nedeni, mekanik ventilasyon süresi, tidal volüm miktarı, kullanılan ventilatör modu, en yüksek ve en düşük fraksiyone oksijen düzeyi, pozitif ekspiryum sonu basınç düzeyi, ventilatörden ayırma yöntemi, ayırma başarısı ve hasta sağ kalım/ölüm bilgileri, retrospektif olarak incelendi. Ventilatörden ayırma yöntemi hariç, tüm veriler, taburcu edilen ve eksitus olan hastalar arasındaki farklılıklar yönünden karşılaştırıldı. Hastaların 16'sının (%44.4) taburcu edildiği, 20'sinin (%55.6) ise, eksitus olduðu gözlendi. Taburcu edilen ve eksitus olan hasta grupları arasında SAPS II skorları, tidal volüm miktarları ve en düşük fraksiyone oksijen düzeyleri açısından istatistiksel olarak anlamlı farklılıklar bulunduğu saptandı. Sonuç olarak, yüksek tidal volümlerin, plato basıncını artırması durumunda, akciğerde biyotravma ve volütravmaya neden olabileceği, yüksek SAPS II skoru ve yüksek fraksiyone oksijen ihtiyacı varlığının, kötü prognozu gösterdiği düşünülmektedir.

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Cite This Article

CAN, M. F., YAĞCI, G., KAYMAKÇIOĞLU, N., GÖRGÜLÜ, S., HARLAK, A., PEKER, Y., ARSLAN, İ., TUFAN, T. (2005). Factors affecting mortality in mechanically ventilated patients in the surgical intensive care unit. Gülhane Tıp Dergisi, Cilt: 47 - Sayı: 3, 209–213. https://ajindex.com/articles/226244

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