Journals / Gülhane Tıp Dergisi / 2000 / Cilt: 42 - Sayı: 2

Case report: Pancytopenia developed following low-dose methotrexate therapy for psoriasis

Pages
198–200
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In such cases use of leukovorin is recommended when bone marrow suppression is suspected.

📌 3 Key Takeaways

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Objective & Hypothesis:Pancytopenia is one of the most serious and unpre¬dictable adverse effects of low dose, pulse methotrexate in treating psoriasis and rheumatoid arthritis.
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Key Findings & Data:We used methotrexate to a 68-year-old man with psoriasis.
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Conclusion & Impact:In such cases use of leukovorin is recommended when bone marrow suppression is suspected.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Pansitopeni · Psoriyazis · Methotreksat

Abstract

Pancytopenia is one of the most serious and unpre¬dictable adverse effects of low dose, pulse methotrexate in treating psoriasis and rheumatoid arthritis. We used methotrexate to a 68-year-old man with psoriasis. After two doses methotrexate therapy, he complicated pancytopenia and developed mucosal bleeding and fever. In such cases use of leukovorin is recommended when bone marrow suppression is suspected.

Özet

Vaka Raporu: Psoriasis için Kullanılan Düşük-Dozda Methotrexate Takiben Gelişen Pansitopeni Olgusu Pansitopeni, psoriasis ve romatoid artrit tedavisinde kullanılan düşük dozda fasılalı methotrexat'in en ciddi ve önceden tahmin edilemeyen yan etkilerinden birisidir. 68 yaşında psöriasisli bir erkek hastada methotrexat kullandık. İki doz methotrexat tedavisinden sonra hastada pansitopeni çıktı ve mukoza kanama ve ateş gelişti. Bu tip vakalarda kemik iliği baskı/anmasından şüphelenildiğinde lökovorin kullanılması önerilmektedir.

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Cite This Article

URAL, A. U., BEYAN, C., KAPTAN, K., AVCU, F., TAŞTAN, B., ÇETİN, T., YALÇIN, A. (2000). Case report: Pancytopenia developed following low-dose methotrexate therapy for psoriasis. Gülhane Tıp Dergisi, Cilt: 42 - Sayı: 2, 198–200. https://ajindex.com/articles/225913