Journals / Gülhane Tıp Dergisi / 2001 / Cilt: 43 - Sayı: 1

The effect of mivacurium and rocuronium on intraocular pressure

Mivakuryum ile rokuronyumun göziçi basıncına etkileri

Pages
49–52
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was concluded that both of the neuromuscular blocker agents could be used safely in the cases which increases in IOP may be hazardous.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of our study was to investigate the effects of equipotent intubating doses of mivacurium and rocuronium on heart rate (HR), mean arterial pressure (MAP) and intraocular pressure (IOP) in patients undergoing elective nonophthalmic surgery. 20patients, American Society of Anesthesiologists"(ASA) I-II, were randomly allocated to receive mivacurium 0.1 mg/kg and thiopenthal sodium 5 mg/kg (Group I) or rocuronium 0.6 mg/kg and thiopenthal sodium 5 mg/kg (Group II) intravenously in induction of anaesthesia.Heart rate (HR), intra-ocular pressure (IOP) and mean arterial pressure (MAP) were measured in both groups; before induction, immediately before intubation, and immediately and 2 minutes after intubation.
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Key Findings & Data:The results of our study showed that, both neuro-muscular blocker agents caused insignificant changes statistically on HR, MAP and IOP.
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Conclusion & Impact:It was concluded that both of the neuromuscular blocker agents could be used safely in the cases which increases in IOP may be hazardous.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Göz içi basınç · Kalp hızı · Kan basıncı

Abstract

The aim of our study was to investigate the effects of equipotent intubating doses of mivacurium and rocuronium on heart rate (HR), mean arterial pressure (MAP) and intraocular pressure (IOP) in patients undergoing elective nonophthalmic surgery. 20patients, American Society of Anesthesiologists"(ASA) I-II, were randomly allocated to receive mivacurium 0.1 mg/kg and thiopenthal sodium 5 mg/kg (Group I) or rocuronium 0.6 mg/kg and thiopenthal sodium 5 mg/kg (Group II) intravenously in induction of anaesthesia.Heart rate (HR), intra-ocular pressure (IOP) and mean arterial pressure (MAP) were measured in both groups; before induction, immediately before intubation, and immediately and 2 minutes after intubation. The results of our study showed that, both neuro-muscular blocker agents caused insignificant changes statistically on HR, MAP and IOP. It was concluded that both of the neuromuscular blocker agents could be used safely in the cases which increases in IOP may be hazardous.

Özet

Çalışmamızda, elektif nonoftalmik cerrahi uygulanan olgularda mivakuryum ve rokuronyumun eş değer dozlarının, kalp atım hızı (KAH), ortalama arter basıncı (OAB) ve göz içi basıncı (GİB) üzerine etkilerini incelemeyi amaçladık. "American Society of Anesthesiologists" (ASA) I-II grubundan 20 olgu rast-gele 2 gruba ayrılarak, indüksiyonda, Grup I (n=10) olgularda 5 mg/kg sodyum tiopental ve 0.1 mg/kg mivakuryum, Grup II (n=10) olgularda ise 5 mg/kg sodyum tiopental ve 0.6 mg/kg rokuronyum uygulandı.Her iki grupta; indüksiyondan önce (I), entübasyon-dan hemen önce (II), entübasyondan hemen (III) ve 2 dk sonra (IV); kalp atım hızı (KAH), ortalama arter basıncı (OAB) ve göz içi basınç (GİB)'ları ölçüldü. Ölçümler sonucunda, her 2 nöromusküler ajanla da OAB, KAH ve GİB'da izlenen değişiklikler istatistiksel açıdan anlamlı bulunmadı.Sonuç olarak, her iki ajanın da, GİB'nın artışının tehlikeli olabileceği oftalmolojik girişimlerde güvenle kullanılabileceği kanısına varıldı.

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Cite This Article

ÖZKAN, S., POÇAN, S., DEMİRKOL, C., ORAL, L., GÖKBEN, M. (2001). The effect of mivacurium and rocuronium on intraocular pressure. Gülhane Tıp Dergisi, Cilt: 43 - Sayı: 1, 49–52. https://ajindex.com/articles/225873